IT8048762A0 - Procedimento per la purificazione di acido ursodesossicolico - Google Patents

Procedimento per la purificazione di acido ursodesossicolico

Info

Publication number: IT8048762A0
Authority: IT; Italy
Prior art keywords: purification; procedure; ursodeoxycholic acid; ursodeoxycholic; acid
Prior art date: 1979-05-23

Application number

IT8048762A

Other languages

English (en)

Other versions

IT1188938B (it

IT8048762A1 (it

Inventor

Armand Guillemette

Abel Francois

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-05-23

Filing date

1980-05-22

Publication date

1980-05-22

1980-05-22 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1980-05-22 Publication of IT8048762A0 publication Critical patent/IT8048762A0/it

1981-11-22 Publication of IT8048762A1 publication Critical patent/IT8048762A1/it

1988-01-28 Application granted granted Critical

1988-01-28 Publication of IT1188938B publication Critical patent/IT1188938B/it

Links

RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
238000000746 purification Methods 0.000 title 1
RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title 1
229960001661 ursodiol Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IT48762/80A 1979-05-23 1980-05-22 Procedimento per la puricazione di acido ursodesossicolico IT1188938B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7913117A FR2457302A1 (fr)	1979-05-23	1979-05-23	Nouveau procede de purification de l'acide ursodesoxycholique

Publications (3)

Publication Number	Publication Date
IT8048762A0 true IT8048762A0 (it)	1980-05-22
IT8048762A1 IT8048762A1 (it)	1981-11-22
IT1188938B IT1188938B (it)	1988-01-28

Family

ID=9225771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT48762/80A IT1188938B (it)	1979-05-23	1980-05-22	Procedimento per la puricazione di acido ursodesossicolico

Country Status (18)

Country	Link
US (1)	US4282161A (it)
JP (1)	JPS55154999A (it)
AU (1)	AU529723B2 (it)
BE (1)	BE883434A (it)
CA (1)	CA1134815A (it)
CH (1)	CH646181A5 (it)
DE (1)	DE3019837A1 (it)
DK (1)	DK145760C (it)
ES (1)	ES489114A1 (it)
FI (1)	FI67388C (it)
FR (1)	FR2457302A1 (it)
GB (1)	GB2052507B (it)
HU (1)	HU182687B (it)
IT (1)	IT1188938B (it)
NL (1)	NL8003000A (it)
PT (1)	PT71271B (it)
SE (1)	SE442119B (it)
ZA (1)	ZA801664B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2444048B1 (it)	1978-12-15	1981-08-14	Roussel Uclaf
IT1132055B (it) *	1980-05-14	1986-06-25	Erregierre Spa	Processo per la preparazione di acido ursodesossicolico ad alta purezza
IT1167478B (it) *	1981-07-24	1987-05-13	Carlo Scolastico	Derivati dell'acido ursodesossicolico
IT1150756B (it) *	1982-04-02	1986-12-17	Zambon Spa	Procedimento per preparare l'acido 3alfa, 7beta-diidrossi-5beta-colanico
DE3930696A1 (de) *	1989-09-14	1991-03-28	Hoechst Ag	Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
EP1392714B1 (en)	2001-03-12	2005-08-31	Intercept Pharmaceuticals, Inc.	Steroids as agonists for fxr
CN114349810A (zh) *	2021-12-30	2022-04-15	北京岳达生物科技有限公司	甾类化合物通用的手性拆分方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2404102C2 (de) *	1974-01-25	1975-11-06	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Reinigung roher Chenodesoxycholsäure
JPS52153954A (en) *	1976-06-18	1977-12-21	Tokyo Tanabe Co	Purification method of ulsodeoxycholic acid

1979
- 1979-05-23 FR FR7913117A patent/FR2457302A1/fr active Granted
1980
- 1980-01-31 SE SE8000776A patent/SE442119B/sv not_active IP Right Cessation
- 1980-03-01 ES ES489114A patent/ES489114A1/es not_active Expired
- 1980-03-21 ZA ZA00801664A patent/ZA801664B/xx unknown
- 1980-04-02 FI FI801054A patent/FI67388C/fi not_active IP Right Cessation
- 1980-04-17 JP JP4963380A patent/JPS55154999A/ja active Granted
- 1980-04-30 DK DK186780A patent/DK145760C/da not_active IP Right Cessation
- 1980-05-05 US US06/146,496 patent/US4282161A/en not_active Expired - Lifetime
- 1980-05-20 PT PT71271A patent/PT71271B/pt unknown
- 1980-05-22 BE BE0/200722A patent/BE883434A/fr not_active IP Right Cessation
- 1980-05-22 HU HU801293A patent/HU182687B/hu not_active IP Right Cessation
- 1980-05-22 AU AU58682/80A patent/AU529723B2/en not_active Ceased
- 1980-05-22 IT IT48762/80A patent/IT1188938B/it active
- 1980-05-22 CH CH401980A patent/CH646181A5/fr not_active IP Right Cessation
- 1980-05-22 CA CA000352535A patent/CA1134815A/fr not_active Expired
- 1980-05-23 GB GB8017124A patent/GB2052507B/en not_active Expired
- 1980-05-23 DE DE19803019837 patent/DE3019837A1/de active Granted
- 1980-05-23 NL NL8003000A patent/NL8003000A/nl not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES489114A1 (es)	1980-08-16
IT1188938B (it)	1988-01-28
GB2052507A (en)	1981-01-28
ZA801664B (en)	1981-03-25
FR2457302B1 (it)	1982-10-15
CA1134815A (fr)	1982-11-02
GB2052507B (en)	1983-08-10
PT71271B (en)	1982-10-15
AU529723B2 (en)	1983-06-16
FI67388C (fi)	1985-03-11
DE3019837C2 (it)	1991-05-16
AU5868280A (en)	1980-11-27
FI801054A7 (fi)	1980-11-24
JPS55154999A (en)	1980-12-02
DK145760B (da)	1983-02-21
NL8003000A (nl)	1980-11-25
BE883434A (fr)	1980-11-24
US4282161A (en)	1981-08-04
PT71271A (fr)	1980-05-31
DK186780A (da)	1980-11-24
DK145760C (da)	1983-08-15
FI67388B (fi)	1984-11-30
CH646181A5 (fr)	1984-11-15
FR2457302A1 (fr)	1980-12-19
SE8000776L (sv)	1980-11-24
DE3019837A1 (de)	1980-11-27
SE442119B (sv)	1985-12-02
HU182687B (en)	1984-02-28
JPS6351156B2 (it)	1988-10-13
IT8048762A1 (it)	1981-11-22

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19960419