IT8223096A0 - Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilala-nina. - Google Patents

Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilala-nina.

Info

Publication number
IT8223096A0
IT8223096A0 IT8223096A IT2309682A IT8223096A0 IT 8223096 A0 IT8223096 A0 IT 8223096A0 IT 8223096 A IT8223096 A IT 8223096A IT 2309682 A IT2309682 A IT 2309682A IT 8223096 A0 IT8223096 A0 IT 8223096A0
Authority
IT
Italy
Prior art keywords
phenyla
aspartyl
alpha
procedure
preparation
Prior art date
Application number
IT8223096A
Other languages
English (en)
Other versions
IT1155060B (it
IT8223096A1 (it
Inventor
Andrea Filippini
Renato Carobbi
Original Assignee
Sirac Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirac Srl filed Critical Sirac Srl
Priority to IT23096/82A priority Critical patent/IT1155060B/it
Publication of IT8223096A0 publication Critical patent/IT8223096A0/it
Priority to US06/447,715 priority patent/US4539147A/en
Priority to EP83106789A priority patent/EP0102483A1/en
Publication of IT8223096A1 publication Critical patent/IT8223096A1/it
Application granted granted Critical
Publication of IT1155060B publication Critical patent/IT1155060B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66Nitrogen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT23096/82A 1982-09-02 1982-09-02 Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina IT1155060B (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT23096/82A IT1155060B (it) 1982-09-02 1982-09-02 Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina
US06/447,715 US4539147A (en) 1982-09-02 1982-12-07 Process for preparing alpha-L-aspartyl-L-phenylalanine alkyl esters
EP83106789A EP0102483A1 (en) 1982-09-02 1983-07-11 Process for preparing alpha-l-aspartyl-l-phenylalanine alkyl esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23096/82A IT1155060B (it) 1982-09-02 1982-09-02 Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina

Publications (3)

Publication Number Publication Date
IT8223096A0 true IT8223096A0 (it) 1982-09-02
IT8223096A1 IT8223096A1 (it) 1984-03-02
IT1155060B IT1155060B (it) 1987-01-21

Family

ID=11203740

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23096/82A IT1155060B (it) 1982-09-02 1982-09-02 Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina

Country Status (3)

Country Link
US (1) US4539147A (it)
EP (1) EP0102483A1 (it)
IT (1) IT1155060B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT8419324A0 (it) * 1984-01-26 1984-01-26 Pierrel Spa Procedimento per la sintesi di derivati n-acilici dell'aspartame.
DE3444915A1 (de) * 1984-12-08 1986-06-12 Hoechst Ag, 6230 Frankfurt N-maleyl-phenylalaninalkylester, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von n-fumarylphenylalaninalkylestern
JPH0680074B2 (ja) * 1985-07-01 1994-10-12 味の素株式会社 N―ホルミル―L―α―アスパルチル―L―フェニルアラニンの製法
DE3532027A1 (de) * 1985-09-09 1987-03-19 Hoechst Ag Verfahren zur herstellung von aspartam und mittel zu seiner durchfuehrung
US5017690A (en) * 1989-08-11 1991-05-21 W. R. Grace & Co.-Conn. Deblocking N-formyl aspartame compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532736A (en) * 1967-11-29 1970-10-06 Lilly Co Eli Novel amino acid protecting group
US3786039A (en) * 1969-04-30 1974-01-15 Ajinomoto Kk Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
DE2830442A1 (de) * 1978-07-11 1980-01-24 Max Planck Gesellschaft Verfahren zur herstellung von polypeptiden
DE3066228D1 (en) * 1980-03-03 1984-04-05 Ajinomoto Kk Process for the production of an alpha-l-aspartyl-l-phenylalanine lower alkyl ester and an intermediate therefor

Also Published As

Publication number Publication date
EP0102483A1 (en) 1984-03-14
US4539147A (en) 1985-09-03
IT1155060B (it) 1987-01-21
IT8223096A1 (it) 1984-03-02

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