IT8421471A0 - Dro-1h-1,4-diazepina ad attivita'derivato di 1-[bis-(4-fluorofenil)calcio antagonista, sua preparaziometil]-4-(3-fenil-2-propenil)-esaine e composizioni che lo contengono - Google Patents

Dro-1h-1,4-diazepina ad attivita'derivato di 1-[bis-(4-fluorofenil)calcio antagonista, sua preparaziometil]-4-(3-fenil-2-propenil)-esaine e composizioni che lo contengono

Info

Publication number
IT8421471A0
IT8421471A0 IT8421471A IT2147184A IT8421471A0 IT 8421471 A0 IT8421471 A0 IT 8421471A0 IT 8421471 A IT8421471 A IT 8421471A IT 2147184 A IT2147184 A IT 2147184A IT 8421471 A0 IT8421471 A0 IT 8421471A0
Authority
IT
Italy
Prior art keywords
hexaine
dro
diazepine
propenyl
fluorophenyl
Prior art date
Application number
IT8421471A
Other languages
English (en)
Other versions
IT1196150B (it
IT8421471A1 (it
Inventor
Gian Giacomo Massaroli
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of IT8421471A0 publication Critical patent/IT8421471A0/it
Priority to IT21471/84A priority Critical patent/IT1196150B/it
Priority to IL75386A priority patent/IL75386A0/xx
Priority to EP85107220A priority patent/EP0166302A3/en
Priority to DE198585107220T priority patent/DE166302T1/de
Priority to KR1019850004283A priority patent/KR860000269A/ko
Priority to JP60132886A priority patent/JPS6117574A/ja
Priority to ES544299A priority patent/ES8609277A1/es
Priority to FI852423A priority patent/FI852423A7/fi
Publication of IT8421471A1 publication Critical patent/IT8421471A1/it
Application granted granted Critical
Publication of IT1196150B publication Critical patent/IT1196150B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT21471/84A 1984-06-19 1984-06-19 Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono IT1196150B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT21471/84A IT1196150B (it) 1984-06-19 1984-06-19 Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono
IL75386A IL75386A0 (en) 1984-06-19 1985-06-03 1-(bis-(4-fluorophenyl)-methyl)-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepine with calcium antagonistic activity,its preparation and compositions containing it
EP85107220A EP0166302A3 (en) 1984-06-19 1985-06-12 "1-[Bis-(4-fluorophyl)methyl]-4-(3-phenyl-2-propenyl)-hexahydro-1H-1,4-diazepine, preparation thereof and compositions containing it
DE198585107220T DE166302T1 (de) 1984-06-19 1985-06-12 1-(reaktion)bis-(4-fluorphenyl)methyli-4-(3-phenyl-2-propenyl)-hexahydro-1h-1,4-diazepin und dieses enthaltende mittel.
KR1019850004283A KR860000269A (ko) 1984-06-19 1985-06-17 칼슘길항성의 1-[비스-(4-플루오로페닐)-메틸-4-(3-페닐-2-프로페닐)-헥사하이드로-1h-1, 4-디아제핀의 제조방법및 이것을 함유한 약학적조성물
JP60132886A JPS6117574A (ja) 1984-06-19 1985-06-18 カルシウム拮抗活性のある１‐〔ビス‐（４‐ルオロフエニル）‐メチル〕‐４‐（３‐フエニル‐２‐プロペニル）‐ヘキサヒドロ‐１ｈ‐１，４‐ジアゼピンとその製法及びそれを含有する医薬組成物
ES544299A ES8609277A1 (es) 1984-06-19 1985-06-18 Procedimiento para la obtencion de 1-(bis-(4-fluorofenil)- metil)-4-(3-fenil-2-propenil)-hexahidro-1h-1, 4-diacepina
FI852423A FI852423A7 (fi) 1984-06-19 1985-06-18 1-(bis(4-fluorofenyyli)-metyyli)- 4-(3-fenyyli-2-propenyyli)-heksahydro-1H-1,4-diatsepiini, jolla on kalsiumin antagonistivaikutus, sen valmistus ja sitä sisältävät seokset.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21471/84A IT1196150B (it) 1984-06-19 1984-06-19 Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono

Publications (3)

Publication Number Publication Date
IT8421471A0 true IT8421471A0 (it) 1984-06-19
IT8421471A1 IT8421471A1 (it) 1985-12-19
IT1196150B IT1196150B (it) 1988-11-10

Family

ID=11182299

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21471/84A IT1196150B (it) 1984-06-19 1984-06-19 Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono

Country Status (8)

Country Link
EP (1) EP0166302A3 (it)
JP (1) JPS6117574A (it)
KR (1) KR860000269A (it)
DE (1) DE166302T1 (it)
ES (1) ES8609277A1 (it)
FI (1) FI852423A7 (it)
IL (1) IL75386A0 (it)
IT (1) IT1196150B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9504662D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
DE69709647T2 (de) * 1996-05-20 2002-11-07 Dupont Pharmaceuticals Research Laboratories, Inc. Cyclischer diarylalkyl diaminederivate als antogoniste von chemokinerezeptoren
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
DK1395567T3 (da) 2001-05-18 2009-04-06 Astrazeneca Ab 4-(phenylpiperazinylmethyl)-benzamidderivater og deres anvendelse til behandling af smerte, angst eller mavetarmslidelser
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
DK1781631T3 (da) 2004-08-02 2012-05-14 Astrazeneca Ab Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790971A (fr) * 1971-11-09 1973-05-07 Janssen Pharmaceutica Nv Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen

Also Published As

Publication number Publication date
FI852423L (fi) 1985-12-20
IT1196150B (it) 1988-11-10
KR860000269A (ko) 1986-01-27
FI852423A0 (fi) 1985-06-18
EP0166302A2 (en) 1986-01-02
EP0166302A3 (en) 1986-03-26
IL75386A0 (en) 1985-10-31
ES544299A0 (es) 1986-09-01
IT8421471A1 (it) 1985-12-19
ES8609277A1 (es) 1986-09-01
FI852423A7 (fi) 1985-12-20
JPS6117574A (ja) 1986-01-25
DE166302T1 (de) 1986-05-22

Similar Documents

Publication Publication Date Title
ATE231336T1 (de) Agrochemische zusammensetzungen von oberflächenaktiven verbindungen
DE3583779D1 (de) Gelzusammensetzungen von liposomen.
DE3575070D1 (de) Analgetische zusammensetzungen.
BR8501657A (pt) Compostos pesticidas de benzoilureia
IT1182092B (it) Composizione germicida per la pulitura di superfici dure
IT8548587A0 (it) Dentifricio anti-placca di aroma migliorato
IT8421471A0 (it) Dro-1h-1,4-diazepina ad attivita'derivato di 1-[bis-(4-fluorofenil)calcio antagonista, sua preparaziometil]-4-(3-fenil-2-propenil)-esaine e composizioni che lo contengono
OA08477A (fr) Compositions d'anticorps monoclonaux humains à protection multiple.
IT1189393B (it) Composti di 1,4-diidropiridina
IT1140978B (it) 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche
IT8848572A0 (it) Fattore di attivazione di leucociti neutrofili, procedimento di preparazione, nonche' composizioni farmaceutiche che lo contengono
IT1213173B (it) Composti ad attivita'antibatterica, procedimento per laloro preparazione e relative composizioni farmaceutiche.
AR240000A1 (es) Composiciones herbicidas
IT8521212A0 (it) Composizioni covulcanizzabili di fluoroelastomeri.
ATA306085A (de) Insektizide zusammensetzungen
IT8123546A0 (it) Composto ad attivita' antiulcera, procedimento per la sua preparazione e composizioni farmaceutiche relative
IT1199948B (it) Composizioni farmaceutiche comprendenti la bromocriptina
IT8422257A0 (it) Miscela di composti diastereoisomeri, ottenuti da (-)-5-(1-idrossi-1-metiletil)-2-metil-2-cicloesen-1-one, avente attivita' mucosecretolitica, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono.
IT1237343B (it) Dicloridrato di acetildicarnitina, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
IT1168068B (it) Composto ad attvita' antiinfiammatoria, disinfettante e antibatterica, procedimento per la sua preparazione e relative composizioni farmaceutiche
FR2572274B1 (fr) Clou d'osteosynthese.
IT1175516B (it) Derivato di acido pirrolcarbossilico ad attivita' analgesica, sua preparazione e composizioni che lo contengono
IT1188706B (it) Composizioni fungicide
FR2567401B1 (fr) Composition de parfum
IT8468187A0 (it) Composizioni di sciampo per capelli