IT8547844A1 - Tavolette di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio - Google Patents

Tavolette di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Info

Publication number
IT8547844A1
IT8547844A1 IT1985A47844A IT4784485A IT8547844A1 IT 8547844 A1 IT8547844 A1 IT 8547844A1 IT 1985A47844 A IT1985A47844 A IT 1985A47844A IT 4784485 A IT4784485 A IT 4784485A IT 8547844 A1 IT8547844 A1 IT 8547844A1
Authority
IT
Italy
Prior art keywords
desrines
tablets
storage
active substance
pharmaceutical active
Prior art date
Application number
IT1985A47844A
Other languages
English (en)
Other versions
IT8547844A0 (it
IT1182723B (it
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IT8547844A0 publication Critical patent/IT8547844A0/it
Publication of IT8547844A1 publication Critical patent/IT8547844A1/it
Application granted granted Critical
Publication of IT1182723B publication Critical patent/IT1182723B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT47844/85A 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio IT1182723B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1465/84A CH658188A5 (de) 1984-03-23 1984-03-23 Lagerstabile schnellzerfallende pharmazeutische presslinge.

Publications (3)

Publication Number Publication Date
IT8547844A0 IT8547844A0 (it) 1985-03-21
IT8547844A1 true IT8547844A1 (it) 1986-09-21
IT1182723B IT1182723B (it) 1987-10-05

Family

ID=4211107

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47844/85A IT1182723B (it) 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Country Status (26)

Country Link
US (1) US4666703A (it)
JP (1) JPS60209518A (it)
AT (1) AT394310B (it)
AU (1) AU579355B2 (it)
BE (1) BE901994A (it)
CA (1) CA1239348A (it)
CH (1) CH658188A5 (it)
DE (1) DE3510129A1 (it)
DK (1) DK162375C (it)
ES (1) ES8702786A1 (it)
FI (1) FI82187C (it)
FR (1) FR2561524B1 (it)
GB (1) GB2157170B (it)
GR (1) GR850717B (it)
HK (1) HK73090A (it)
IE (1) IE57954B1 (it)
IL (1) IL74666A (it)
IT (1) IT1182723B (it)
LU (1) LU85817A1 (it)
NL (1) NL8500856A (it)
NO (1) NO170125C (it)
NZ (1) NZ211537A (it)
PT (1) PT80147B (it)
SE (1) SE8501370L (it)
SG (1) SG46890G (it)
ZA (1) ZA852160B (it)

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IT1197316B (it) * 1986-10-01 1988-11-30 Proter Spa Formulazione galenica ad uso orale di derivati della reina a lento rilascio per impiego terapeutico
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
EP0273209B1 (en) * 1986-12-30 1992-01-15 American Cyanamid Company Composition of matter containing polycarbophil
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
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US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US4904477A (en) * 1987-07-08 1990-02-27 American Home Products Corporation Spray dried ibuprofen compositions
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
DE3937455A1 (de) * 1989-11-10 1991-05-16 Nordmark Arzneimittel Gmbh Antacidatabletten
EP0462066A1 (en) * 1990-06-15 1991-12-18 Warner-Lambert Company Amorphous gemfibrozil
SK282072B6 (sk) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Tableta s obsahom lamotrigínu dispergovateľná vo vode a spôsob jej prípravy
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
DE4317172A1 (de) * 1993-05-22 1995-01-05 Rhone Poulenc Rorer Gmbh Geschmacksneutrale und schnellfreisetzende Buflomedil-Hydrochlorid-Arzneiform und Herstellungsverfahren desselben
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
DE69633018T2 (de) * 1995-11-14 2004-12-09 Abbott Gmbh & Co. Kg Schilddrüsenhormone enthaltende stabilisierte arzneimittel und verfahren
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
ES2188928T3 (es) * 1996-04-26 2003-07-01 Shionogi & Co Pastilla de liberador-rapido s1452.
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
HU221435B (en) * 1998-02-20 2002-10-28 Egyt Gyogyszervegyeszeti Gyar Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production
FR2781793B1 (fr) 1998-08-03 2001-07-20 Prographarm Lab Procede de fabrication de granules de gabapentine enrobes
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
ES2284643T3 (es) 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
IL155959A0 (en) 2000-11-28 2003-12-23 Fmc Corp Edible pga (propylene glycol alginate) coating composition
US7067148B2 (en) * 2001-02-15 2006-06-27 King Pharmaceutical Research & Development, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030171436A1 (en) * 2001-10-29 2003-09-11 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
US20030099699A1 (en) 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
JP4551092B2 (ja) * 2002-03-06 2010-09-22 協和発酵キリン株式会社 口腔内速崩壊性錠剤
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
AU2007266574A1 (en) * 2006-06-01 2007-12-06 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
US20100092564A1 (en) * 2006-12-21 2010-04-15 Jae Han Park Composition of and Method for Preparing Orally Disintegrating Tablets
US20100055179A1 (en) * 2006-12-21 2010-03-04 Mallinckrodt Inc. Composition of and Method for Preparing Orally Disintegrating Tablets Containing a High Dose of Pharmaceutically Active Ingredients
CN101380474B (zh) * 2007-09-06 2012-07-25 北京大学 用于口服制剂的pH敏感性固体药物组合物及制备方法
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

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DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
BE785702A (fr) * 1971-07-14 1972-10-16 Roehm Gmbh Produits de revetement de formes medicamenteuses et leur utilisation
GB1540754A (en) * 1976-03-10 1979-02-14 Wellcome Found Tablet formulation
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4505896A (en) * 1979-04-19 1985-03-19 Elorac, Ltd. Method of treating acne vulgaris and composition
CH642809B (fr) * 1980-11-07 Longines Montres Comp D Montre avec un mecanisme de quantieme perpetuel.
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
ATE13486T1 (de) * 1980-11-12 1985-06-15 Ciba Geigy Ag Schnellzerfallende arzneimittel-presslinge.
IT1168014B (it) * 1981-08-05 1987-05-20 Erba Farmitalia Forme farmaceutiche a cessione protratta

Also Published As

Publication number Publication date
IL74666A (en) 1988-11-30
DK130685D0 (da) 1985-03-22
US4666703A (en) 1987-05-19
FR2561524A1 (fr) 1985-09-27
BE901994A (fr) 1985-09-23
ES8702786A1 (es) 1987-01-16
CH658188A5 (de) 1986-10-31
IL74666A0 (en) 1985-06-30
DK130685A (da) 1985-09-24
NO170125C (no) 1992-09-16
AU579355B2 (en) 1988-11-24
GR850717B (it) 1985-07-19
NO851170L (no) 1985-09-24
DK162375C (da) 1992-03-09
NZ211537A (en) 1988-03-30
LU85817A1 (de) 1985-12-12
GB2157170B (en) 1988-01-20
PT80147A (en) 1985-04-01
ATA86885A (de) 1991-09-15
NL8500856A (nl) 1985-10-16
NO170125B (no) 1992-06-09
FR2561524B1 (fr) 1990-01-12
FI82187C (fi) 1991-02-11
JPH0574568B2 (it) 1993-10-18
AU4028785A (en) 1985-09-26
PT80147B (pt) 1987-10-20
ZA852160B (en) 1985-11-27
FI82187B (fi) 1990-10-31
ES541513A0 (es) 1987-01-16
SE8501370D0 (sv) 1985-03-20
IE57954B1 (en) 1993-05-19
JPS60209518A (ja) 1985-10-22
IT8547844A0 (it) 1985-03-21
SE8501370L (sv) 1985-09-24
FI851114A0 (fi) 1985-03-20
FI851114L (fi) 1985-09-24
DE3510129A1 (de) 1985-10-03
GB8506758D0 (en) 1985-04-17
IT1182723B (it) 1987-10-05
HK73090A (en) 1990-09-21
GB2157170A (en) 1985-10-23
AT394310B (de) 1992-03-10
DK162375B (da) 1991-10-21
SG46890G (en) 1990-08-17
CA1239348A (en) 1988-07-19
IE850744L (en) 1985-09-23

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940322