IT8720436A0 - Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido. - Google Patents

Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.

Info

Publication number
IT8720436A0
IT8720436A0 IT8720436A IT2043687A IT8720436A0 IT 8720436 A0 IT8720436 A0 IT 8720436A0 IT 8720436 A IT8720436 A IT 8720436A IT 2043687 A IT2043687 A IT 2043687A IT 8720436 A0 IT8720436 A0 IT 8720436A0
Authority
IT
Italy
Prior art keywords
piperidinil
piri
diamino
din
oxide
Prior art date
Application number
IT8720436A
Other languages
English (en)
Other versions
IT1212140B (it
Inventor
Claudio Botre
Original Assignee
Sig Gla Pharmaceuticals S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sig Gla Pharmaceuticals S P A filed Critical Sig Gla Pharmaceuticals S P A
Priority to IT8720436A priority Critical patent/IT1212140B/it
Publication of IT8720436A0 publication Critical patent/IT8720436A0/it
Priority to BE8700791A priority patent/BE1000745A4/fr
Priority to DE8888830189T priority patent/DE3872956T2/de
Priority to AT88830189T priority patent/ATE78473T1/de
Priority to EP88830189A priority patent/EP0295218B1/en
Priority to ES88830189T priority patent/ES2042799T3/es
Application granted granted Critical
Publication of IT1212140B publication Critical patent/IT1212140B/it
Priority to GR920402375T priority patent/GR3006050T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IT8720436A 1987-05-08 1987-05-08 Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido. IT1212140B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8720436A IT1212140B (it) 1987-05-08 1987-05-08 Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.
BE8700791A BE1000745A4 (fr) 1987-05-08 1987-07-16 Procede de preparation de 2,4-diamino-6-(1-piperidinyl)-pyrimidine-n-oxyde.
DE8888830189T DE3872956T2 (de) 1987-05-08 1988-05-03 Verfahren zur herstellung von 2,4-diamino-6-(1-piperidinyl)-pyramidin-n-oxid.
AT88830189T ATE78473T1 (de) 1987-05-08 1988-05-03 Verfahren zur herstellung von 2,4-diamino-6-(1piperidinyl)-pyramidin-n-oxid.
EP88830189A EP0295218B1 (en) 1987-05-08 1988-05-03 A process for the preparation of 2,4-diamino-6-(1-piperidinyl)-pyrimidine n-oxide
ES88830189T ES2042799T3 (es) 1987-05-08 1988-05-03 Un procedimiento para la preparacion del n-oxido de la 2,4-diamino-6-(1-piperidinil)pirimidina.
GR920402375T GR3006050T3 (it) 1987-05-08 1992-10-22

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8720436A IT1212140B (it) 1987-05-08 1987-05-08 Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.

Publications (2)

Publication Number Publication Date
IT8720436A0 true IT8720436A0 (it) 1987-05-08
IT1212140B IT1212140B (it) 1989-11-08

Family

ID=11166913

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8720436A IT1212140B (it) 1987-05-08 1987-05-08 Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.

Country Status (7)

Country Link
EP (1) EP0295218B1 (it)
AT (1) ATE78473T1 (it)
BE (1) BE1000745A4 (it)
DE (1) DE3872956T2 (it)
ES (1) ES2042799T3 (it)
GR (1) GR3006050T3 (it)
IT (1) IT1212140B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI367208B (en) 2004-11-12 2012-07-01 Sumitomo Chemical Co Production method of pyrimidine compounds
GB2451594A (en) * 2006-03-15 2009-02-04 Csir Modulation of phosphoryl transferase activity of glutamine synthetase
EP2008210A1 (en) * 2006-03-15 2008-12-31 Csir Modulation of phosphoryl transferase activity of glutamine synthetase
CN107235919B (zh) * 2017-06-22 2020-05-12 安徽拜善晟制药有限公司 一种米诺地尔的合成工艺
CN110272391B (zh) * 2019-07-03 2022-10-28 天津药物研究院药业有限责任公司 一种米诺地尔的精制方法
CN114394941A (zh) * 2022-02-16 2022-04-26 汉瑞药业(荆门)有限公司 一种2,4-二氨基-6-氯嘧啶的制备方法
CN117247357A (zh) * 2023-09-20 2023-12-19 吉林大学 一种米诺地尔的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382248A (en) * 1965-11-01 1968-05-07 Upjohn Co 6-amino-4, 5-di(substituted amino)-1, 2-dihydro-1-hydroxy-2-iminopyrimidines

Also Published As

Publication number Publication date
EP0295218A1 (en) 1988-12-14
ES2042799T3 (es) 1993-12-16
EP0295218B1 (en) 1992-07-22
BE1000745A4 (fr) 1989-03-28
ATE78473T1 (de) 1992-08-15
GR3006050T3 (it) 1993-06-21
DE3872956D1 (de) 1992-08-27
DE3872956T2 (de) 1992-12-03
IT1212140B (it) 1989-11-08

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