IT8820741A0 - Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori. - Google Patents

Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori.

Info

Publication number
IT8820741A0
IT8820741A0 IT8820741A IT2074188A IT8820741A0 IT 8820741 A0 IT8820741 A0 IT 8820741A0 IT 8820741 A IT8820741 A IT 8820741A IT 2074188 A IT2074188 A IT 2074188A IT 8820741 A0 IT8820741 A0 IT 8820741A0
Authority
IT
Italy
Prior art keywords
monoclonal antibody
antibody
tumors
diagnosis
transformed
Prior art date
Application number
IT8820741A
Other languages
English (en)
Other versions
IT1217724B (it
Inventor
Luciano Zardi
Original Assignee
Ist Naz Ric Sul Cancro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Naz Ric Sul Cancro filed Critical Ist Naz Ric Sul Cancro
Priority to IT20741/88A priority Critical patent/IT1217724B/it
Publication of IT8820741A0 publication Critical patent/IT8820741A0/it
Priority to EP89830234A priority patent/EP0344134B1/en
Priority to DE89830234T priority patent/DE68912403T2/de
Priority to AT89830234T priority patent/ATE100471T1/de
Application granted granted Critical
Publication of IT1217724B publication Critical patent/IT1217724B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT20741/88A 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori IT1217724B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori
EP89830234A EP0344134B1 (en) 1988-05-26 1989-05-25 Monoclonal antibody specific to a fibronectin sequence expressed in transformed cells, hybridoma secreting said antibody and use of said monoclonal antibody in the diagnosis of tumors
DE89830234T DE68912403T2 (de) 1988-05-26 1989-05-25 Monoklonaler Antikörper, spezifisch für eine in transformierten Zellen exprimierte Fibronectin-Sequenz, Hybridoma, das diesen Antikörper erzeugt und Verwendung dieses monoklonalen Antikörpers zur Diagnose von Tumoren.
AT89830234T ATE100471T1 (de) 1988-05-26 1989-05-25 Monoklonaler antikoerper, spezifisch fuer eine in transformierten zellen exprimierte fibronectinsequenz, hybridoma, das diesen antikoerper erzeugt und verwendung dieses monoklonalen antikoerpers zur diagnose von tumoren.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori

Publications (2)

Publication Number Publication Date
IT8820741A0 true IT8820741A0 (it) 1988-05-26
IT1217724B IT1217724B (it) 1990-03-30

Family

ID=11171367

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20741/88A IT1217724B (it) 1988-05-26 1988-05-26 Anticorpo monoclonale specifico per una sequenza di fibronettina espressa in cellule trasformate ibridoma secernente tale anticorpo e impiego dell'anticorpo monoclonale per la diagnosi di tumori

Country Status (4)

Country Link
EP (1) EP0344134B1 (it)
AT (1) ATE100471T1 (it)
DE (1) DE68912403T2 (it)
IT (1) IT1217724B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI892197A7 (fi) * 1989-05-08 1990-11-09 Locus Oy Foerfarande foer detektering av tumoerer.
EP0522086B1 (en) * 1990-03-12 1994-07-20 The Biomembrane Institute DNA SEQUENCE ENCODING GALACTOPROTEIN b3
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
ES2590912T3 (es) 1997-12-08 2016-11-24 Merck Patent Gmbh Proteínas de fusión heterodiméricas útiles para inmunoterapia dirigida y estimulación general del sistema inmunitario
GB9726539D0 (en) 1997-12-16 1998-02-11 Univ Dundee Polypeptides, polynucleotides and uses thereof
HUP0204475A2 (en) 2000-02-11 2003-04-28 Merck Patent Gmbh Enhancing the circulating half-life of antibody-based fusion proteins
JP2003524018A (ja) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ フィブロネクチンのｅｄ‐ｂドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用
AU2001239470A1 (en) 2000-02-24 2001-09-03 Philogen S.R.L. Compositions and methods for treatment of angiogenesis in pathological lesions
KR20030064275A (ko) 2000-06-29 2003-07-31 메르크 파텐트 게엠베하 면역싸이토카인 흡수 증강제와의 조합 치료에 의한항체-싸이토카인 융합 단백질 매개 면역 반응 증강
RU2003129528A (ru) 2001-03-07 2005-04-10 Мерк Патент ГмбХ (DE) Способ экспрессии белков, содержащих в качестве компонента гибридный изотип антитела
EP1383785B1 (en) 2001-05-03 2011-03-16 Merck Patent GmbH Recombinant tumor specific antibody and use thereof
DK1454138T3 (da) 2001-12-04 2012-02-13 Merck Patent Gmbh Immunocytokiner med moduleret selektivitet
RU2370276C2 (ru) 2003-12-31 2009-10-20 Мерк Патент Гмбх Fc-ЭРИТРОПОЭТИН СЛИТЫЙ БЕЛОК С УЛУЧШЕННОЙ ФАРМАКОКИНЕТИКОЙ
EP1702069A2 (en) 2004-01-05 2006-09-20 EMD Lexigen Research Center Corp. Interleukin-12 targeted to oncofoetal fibronectin
AU2005206277B2 (en) 2004-01-22 2011-06-23 Merck Patent Gmbh Anti-cancer antibodies with reduced complement fixation
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
ES2365046T3 (es) 2005-12-30 2011-09-21 Merck Patent Gmbh Anticuerpos anti-cd19 con inmunogenicidad reducida.
WO2008120101A2 (en) 2007-04-02 2008-10-09 Philogen S.P.A. The ed-a antigen of fibrinogen is associated with the neovasculature of tumour metastases
US10202442B2 (en) 2007-07-25 2019-02-12 Philogen S.P.A. Antigen associated with lung cancers and lymphomas
DK3281952T3 (da) 2007-10-30 2020-08-03 Philogen Spa Antigen, der er forbundet med reumatoid artritis
EP2100621A1 (en) 2008-03-10 2009-09-16 mivenion GmbH Polyether polyol dendron conjugates with effector molecules for biological targeting
EP2461832B1 (en) 2009-08-05 2017-06-28 Philogen S.p.A. Targeting of bone marrow neovasculature
ES2743423T3 (es) 2012-10-03 2020-02-19 Philogen Spa Conjugado de anticuerpos para su uso en el tratamiento de una enfermedad inflamatoria intestinal

Also Published As

Publication number Publication date
DE68912403D1 (de) 1994-03-03
EP0344134A2 (en) 1989-11-29
ATE100471T1 (de) 1994-02-15
EP0344134A3 (en) 1990-08-08
IT1217724B (it) 1990-03-30
EP0344134B1 (en) 1994-01-19
DE68912403T2 (de) 1994-05-11

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