IT9020020A0 - "n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono - Google Patents

"n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono

Info

Publication number: IT9020020A0
Authority: IT; Italy
Prior art keywords: ditrimethoxybenzoilpiperazines; substituted; procedure; contain; preparation
Prior art date: 1989-04-15

Application number

IT9020020A

Other languages

English (en)

Other versions

IT1241631B (it

IT9020020A1 (it

Inventor

Pierre Braquet

Eduardo Pirotzky

Jean-Jacques Godfroid

Francoise Heymans

Original Assignee

Scras

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-15

Filing date

1990-04-12

Publication date

1990-04-12

1990-04-12 Application filed by Scras filed Critical Scras

1990-04-12 Publication of IT9020020A0 publication Critical patent/IT9020020A0/it

1991-10-12 Publication of IT9020020A1 publication Critical patent/IT9020020A1/it

1994-01-25 Application granted granted Critical

1994-01-25 Publication of IT1241631B publication Critical patent/IT1241631B/it

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IT20020A 1989-04-15 1990-04-12 "n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono IT1241631B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898908587A GB8908587D0 (en)	1989-04-15	1989-04-15	New 2-substituted n,n'-ditrimethoxybenzoyl piperazines

Publications (3)

Publication Number	Publication Date
IT9020020A0 true IT9020020A0 (it)	1990-04-12
IT9020020A1 IT9020020A1 (it)	1991-10-12
IT1241631B IT1241631B (it)	1994-01-25

Family

ID=10655129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT20020A IT1241631B (it)	1989-04-15	1990-04-12	"n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono

Country Status (32)

Country	Link
US (1)	US5019576A (it)
JP (1)	JP2633709B2 (it)
KR (1)	KR900016178A (it)
AR (1)	AR247736A1 (it)
AT (1)	AT399337B (it)
AU (1)	AU631334B2 (it)
BE (1)	BE1007245A3 (it)
CA (1)	CA2014521C (it)
CH (1)	CH681301A5 (it)
DE (1)	DE4011925A1 (it)
DK (1)	DK91890A (it)
DZ (1)	DZ1407A1 (it)
ES (1)	ES2019554A6 (it)
FI (1)	FI92058C (it)
FR (2)	FR2645743B1 (it)
GB (2)	GB8908587D0 (it)
GR (1)	GR1000355B (it)
HK (1)	HK95092A (it)
IE (1)	IE65058B1 (it)
IN (1)	IN175799B (it)
IT (1)	IT1241631B (it)
LU (1)	LU87719A1 (it)
MA (1)	MA21805A1 (it)
NL (1)	NL9000798A (it)
NO (1)	NO176098C (it)
NZ (1)	NZ233250A (it)
OA (1)	OA09446A (it)
PT (1)	PT93736B (it)
SE (1)	SE505186C2 (it)
SG (1)	SG92092G (it)
TN (1)	TNSN90051A1 (it)
ZA (1)	ZA902566B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5344830A (en) *	1992-12-10	1994-09-06	Merck & Co., Inc.	N,N-diacylpiperazine tachykinin antagonists
IL111730A (en) *	1993-11-29	1998-12-06	Fujisawa Pharmaceutical Co	Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US5883098A (en) *	1993-11-29	1999-03-16	Fujisawa Pharmaceutical Co., Ltd.	Piperazine derivatives
US5610165A (en) *	1994-02-17	1997-03-11	Merck & Co., Inc.	N-acylpiperidine tachykinin antagonists
US5795894A (en) *	1995-05-02	1998-08-18	Schering Corporation	Piperazino derivatives as neurokinn antagonists
JP4173912B2 (ja) *	1995-05-02	2008-10-29	シェーリングコーポレイション	ニューロキニンアンタゴニストとしてのピペラジノ誘導体
US5892039A (en) *	1995-08-31	1999-04-06	Schering Corporation	Piperazino derivatives as neurokinin antagonists
BR9610277A (pt) *	1995-08-31	1999-07-06	Schering Corp	Derivados de piperazino como antagonistas de neurowuinina
US5869488A (en) *	1996-05-01	1999-02-09	Schering Corporation	Piperazino derivatives as neurokinin antagonists
FR2780649B1 (fr) *	1998-07-06	2001-03-09	Univ Paris Vii Denis Diderot	Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1243991A (en) *	1968-06-10	1971-08-25	Ici Ltd	Piperidine, morpholine and piperazine derivatives
FR2209560A1 (en) *	1972-12-07	1974-07-05	Degussa	N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
IL85700A0 (en) *	1987-03-24	1988-08-31	Takeda Chemical Industries Ltd	1,4-disubstituted piperazine compounds,their production and use
EP0318235A3 (en) *	1987-11-25	1991-05-02	Takeda Chemical Industries, Ltd.	Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
KR900018073A (ko) *	1988-05-23	1990-12-20	추후보충	피페라진 화합물
GB8823776D0 (en) *	1988-10-11	1988-11-16	Scras	New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823775D0 (en) *	1988-10-11	1988-11-16	Scras	New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) *	1988-11-11	1991-03-05	Takeda Chemical Industries, Ltd.	Trisubstituted piperazine compounds, their production and use

1989
- 1989-04-15 GB GB898908587A patent/GB8908587D0/en active Pending
1990
- 1990-04-03 ZA ZA902566A patent/ZA902566B/xx unknown
- 1990-04-04 GB GB9007612A patent/GB2230262B/en not_active Expired - Lifetime
- 1990-04-05 NL NL9000798A patent/NL9000798A/nl not_active Application Discontinuation
- 1990-04-05 IN IN140DE1990D patent/IN175799B/en unknown
- 1990-04-06 SE SE9001269A patent/SE505186C2/sv not_active IP Right Cessation
- 1990-04-06 GR GR900100270A patent/GR1000355B/el unknown
- 1990-04-09 US US07/506,421 patent/US5019576A/en not_active Expired - Lifetime
- 1990-04-09 NZ NZ233250A patent/NZ233250A/en unknown
- 1990-04-10 LU LU87719A patent/LU87719A1/fr unknown
- 1990-04-10 CH CH1206/90A patent/CH681301A5/fr not_active IP Right Cessation
- 1990-04-10 NO NO901631A patent/NO176098C/no unknown
- 1990-04-10 AR AR90316593A patent/AR247736A1/es active
- 1990-04-10 MA MA22064A patent/MA21805A1/fr unknown
- 1990-04-11 ES ES9001056A patent/ES2019554A6/es not_active Expired - Lifetime
- 1990-04-11 DK DK091890A patent/DK91890A/da unknown
- 1990-04-11 IE IE131490A patent/IE65058B1/en not_active IP Right Cessation
- 1990-04-11 DZ DZ900066A patent/DZ1407A1/fr active
- 1990-04-11 BE BE9000408A patent/BE1007245A3/fr not_active IP Right Cessation
- 1990-04-11 PT PT93736A patent/PT93736B/pt not_active IP Right Cessation
- 1990-04-11 AT AT0086690A patent/AT399337B/de not_active IP Right Cessation
- 1990-04-12 DE DE4011925A patent/DE4011925A1/de not_active Ceased
- 1990-04-12 CA CA002014521A patent/CA2014521C/en not_active Expired - Fee Related
- 1990-04-12 TN TNTNSN90051A patent/TNSN90051A1/fr unknown
- 1990-04-12 IT IT20020A patent/IT1241631B/it active IP Right Grant
- 1990-04-12 OA OA59775A patent/OA09446A/xx unknown
- 1990-04-12 FI FI901883A patent/FI92058C/fi not_active IP Right Cessation
- 1990-04-13 JP JP2096620A patent/JP2633709B2/ja not_active Expired - Lifetime
- 1990-04-13 FR FR909004797A patent/FR2645743B1/fr not_active Expired - Lifetime
- 1990-04-13 FR FR909004798A patent/FR2645859B1/fr not_active Expired - Lifetime
- 1990-04-14 KR KR1019900005198A patent/KR900016178A/ko not_active Ceased
- 1990-04-17 AU AU53261/90A patent/AU631334B2/en not_active Ceased
1992
- 1992-09-11 SG SG920/92A patent/SG92092G/en unknown
- 1992-11-26 HK HK950/92A patent/HK95092A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATA86690A (de)	1994-09-15
HK95092A (en)	1992-12-04
NO176098C (no)	1995-02-01
GB8908587D0 (en)	1989-06-01
MA21805A1 (fr)	1990-12-31
IN175799B (it)	1995-08-26
PT93736A (pt)	1990-11-20
GR1000355B (el)	1992-06-25
NZ233250A (en)	1991-03-26
DK91890A (da)	1990-10-16
US5019576A (en)	1991-05-28
ES2019554A6 (es)	1991-06-16
NO901631D0 (no)	1990-04-10
AR247736A1 (es)	1995-03-31
AU5326190A (en)	1990-11-01
GB2230262A (en)	1990-10-17
TNSN90051A1 (fr)	1991-03-05
NO901631L (no)	1990-10-16
DK91890D0 (da)	1990-04-11
ZA902566B (en)	1991-01-30
SG92092G (en)	1992-12-04
FI901883A0 (fi)	1990-04-12
DZ1407A1 (fr)	2004-09-13
JP2633709B2 (ja)	1997-07-23
JPH02292266A (ja)	1990-12-03
GR900100270A (en)	1991-09-27
CA2014521C (en)	1997-09-09
KR900016178A (ko)	1990-11-12
SE505186C2 (sv)	1997-07-14
FR2645743B1 (fr)	1992-06-05
BE1007245A3 (fr)	1995-05-02
IT1241631B (it)	1994-01-25
GB9007612D0 (en)	1990-05-30
LU87719A1 (fr)	1990-07-24
FI92058B (fi)	1994-06-15
DE4011925A1 (de)	1990-10-18
AU631334B2 (en)	1992-11-19
CH681301A5 (it)	1993-02-26
FR2645859A1 (fr)	1990-10-19
SE9001269L (sv)	1990-10-16
IE65058B1 (en)	1995-10-04
PT93736B (pt)	1996-09-30
IT9020020A1 (it)	1991-10-12
NL9000798A (nl)	1990-11-01
SE9001269D0 (sv)	1990-04-06
AT399337B (de)	1995-04-25
CA2014521A1 (en)	1990-10-15
IE901314L (en)	1990-10-15
GB2230262B (en)	1992-02-26
OA09446A (fr)	1992-10-15
FR2645743A1 (fr)	1990-10-19
FR2645859B1 (fr)	1992-06-05
NO176098B (no)	1994-10-24
FI92058C (fi)	1994-09-26

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Legal Events

Date	Code	Title	Description
1994-01-25	0001	Granted
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970506