ITMI20011925A0 - Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino - Google Patents
Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallinoInfo
- Publication number
- ITMI20011925A0 ITMI20011925A0 IT2001MI001925A ITMI20011925A ITMI20011925A0 IT MI20011925 A0 ITMI20011925 A0 IT MI20011925A0 IT 2001MI001925 A IT2001MI001925 A IT 2001MI001925A IT MI20011925 A ITMI20011925 A IT MI20011925A IT MI20011925 A0 ITMI20011925 A0 IT MI20011925A0
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- industrial scale
- method applicable
- crystalline cefuroxime
- axetile
- Prior art date
Links
- JFPVXVDWJQMJEE-IZRZKJBUSA-N cefuroxime Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 JFPVXVDWJQMJEE-IZRZKJBUSA-N 0.000 title 1
- 229960001668 cefuroxime Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001925A ITMI20011925A1 (it) | 2001-09-14 | 2001-09-14 | Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino |
| EP02774564A EP1425285A1 (en) | 2001-09-14 | 2002-09-04 | Process for the preparation of crystalline cefuromixe axetil |
| US10/489,321 US20040242864A1 (en) | 2001-09-14 | 2002-09-04 | Process for the preparation of crystalline cefuroxime axetil |
| KR10-2004-7003595A KR20040053124A (ko) | 2001-09-14 | 2002-09-04 | 결정성 세푸록심 악세틸의 제조방법 |
| PCT/EP2002/009896 WO2003024977A1 (en) | 2001-09-14 | 2002-09-04 | Process for the preparation of crystalline cefuromixe axetil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001925A ITMI20011925A1 (it) | 2001-09-14 | 2001-09-14 | Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI20011925A0 true ITMI20011925A0 (it) | 2001-09-14 |
| ITMI20011925A1 ITMI20011925A1 (it) | 2003-03-14 |
Family
ID=11448376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2001MI001925A ITMI20011925A1 (it) | 2001-09-14 | 2001-09-14 | Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20040242864A1 (it) |
| EP (1) | EP1425285A1 (it) |
| KR (1) | KR20040053124A (it) |
| IT (1) | ITMI20011925A1 (it) |
| WO (1) | WO2003024977A1 (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1409492B1 (en) * | 2001-07-25 | 2008-10-15 | Lupin Limited | An improved method for preparation of cefuroxime axetil |
| ITMI20011763A1 (it) * | 2001-08-10 | 2003-02-10 | Antibioticos Spa | Processo di preparazione di cefuroxime axelite ad elevata purezza |
| US6537985B1 (en) * | 2001-11-30 | 2003-03-25 | Phoenix Scientific, Inc. | Antibiotic formulation and a method of making this formulation |
| CN100448879C (zh) * | 2004-07-22 | 2009-01-07 | 北京化工大学 | 一种无定型头孢呋辛酯的制备方法 |
| CN106554361B (zh) * | 2016-09-30 | 2018-10-09 | 华北制药河北华民药业有限责任公司 | 一种头孢呋辛酯口服制剂的制备方法 |
| CN118307558A (zh) * | 2024-03-26 | 2024-07-09 | 华北制药河北华民药业有限责任公司 | 一种头孢呋辛酯双相结晶的制备方法 |
| CN118480056A (zh) * | 2024-04-26 | 2024-08-13 | 广东立国制药有限公司 | 一种提高头孢呋辛酯转化率的合成方法、应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1571683A (en) * | 1976-02-16 | 1980-07-16 | Glaxo Operations Ltd | Ester derivatives of cefuroxime |
| YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
| GB8320521D0 (en) * | 1983-07-29 | 1983-09-01 | Glaxo Group Ltd | Chemical process |
| GB8320520D0 (en) * | 1983-07-29 | 1983-09-01 | Glaxo Group Ltd | Chemical process |
| TW293010B (en) * | 1994-04-20 | 1996-12-11 | Hui-Po Wang | Method for preparing cephalosporin derivatives |
| IT1277426B1 (it) * | 1995-08-03 | 1997-11-10 | Acs Dobfar Spa | Forma cristallina biodisponibile del cefuroxima axetil |
| EP1409492B1 (en) * | 2001-07-25 | 2008-10-15 | Lupin Limited | An improved method for preparation of cefuroxime axetil |
| ITMI20011763A1 (it) * | 2001-08-10 | 2003-02-10 | Antibioticos Spa | Processo di preparazione di cefuroxime axelite ad elevata purezza |
-
2001
- 2001-09-14 IT IT2001MI001925A patent/ITMI20011925A1/it unknown
-
2002
- 2002-09-04 KR KR10-2004-7003595A patent/KR20040053124A/ko not_active Withdrawn
- 2002-09-04 WO PCT/EP2002/009896 patent/WO2003024977A1/en not_active Ceased
- 2002-09-04 US US10/489,321 patent/US20040242864A1/en not_active Abandoned
- 2002-09-04 EP EP02774564A patent/EP1425285A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003024977A1 (en) | 2003-03-27 |
| ITMI20011925A1 (it) | 2003-03-14 |
| US20040242864A1 (en) | 2004-12-02 |
| KR20040053124A (ko) | 2004-06-23 |
| EP1425285A1 (en) | 2004-06-09 |
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