ITMI20031790A1 - Antagonistici abiotici dell'eparina. - Google Patents
Antagonistici abiotici dell'eparina.Info
- Publication number
- ITMI20031790A1 ITMI20031790A1 IT001790A ITMI20031790A ITMI20031790A1 IT MI20031790 A1 ITMI20031790 A1 IT MI20031790A1 IT 001790 A IT001790 A IT 001790A IT MI20031790 A ITMI20031790 A IT MI20031790A IT MI20031790 A1 ITMI20031790 A1 IT MI20031790A1
- Authority
- IT
- Italy
- Prior art keywords
- eparine
- antagonistics
- abiotic
- heparin
- binding
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- VTJUKNSKBAOEHE-UHFFFAOYSA-N calixarene Chemical class COC(=O)COC1=C(CC=2C(=C(CC=3C(=C(C4)C=C(C=3)C(C)(C)C)OCC(=O)OC)C=C(C=2)C(C)(C)C)OCC(=O)OC)C=C(C(C)(C)C)C=C1CC1=C(OCC(=O)OC)C4=CC(C(C)(C)C)=C1 VTJUKNSKBAOEHE-UHFFFAOYSA-N 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001790A ITMI20031790A1 (it) | 2003-09-19 | 2003-09-19 | Antagonistici abiotici dell'eparina. |
| AT04765261T ATE397583T1 (de) | 2003-09-19 | 2004-09-16 | Abiotische heparinantagonisten |
| US10/572,387 US7465820B2 (en) | 2003-09-19 | 2004-09-16 | Abiotic heparin antagonists |
| DE602004014285T DE602004014285D1 (de) | 2003-09-19 | 2004-09-16 | Abiotische heparinantagonisten |
| EP04765261A EP1663952B1 (en) | 2003-09-19 | 2004-09-16 | Abiotic heparin antagonists |
| PCT/EP2004/010358 WO2005028422A1 (en) | 2003-09-19 | 2004-09-16 | Abiotic heparin antagonists |
| CA002539301A CA2539301A1 (en) | 2003-09-19 | 2004-09-16 | Abiotic heparin antagonists |
| CNB2004800267604A CN100390136C (zh) | 2003-09-19 | 2004-09-16 | 非生物的肝素拮抗剂 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001790A ITMI20031790A1 (it) | 2003-09-19 | 2003-09-19 | Antagonistici abiotici dell'eparina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITMI20031790A1 true ITMI20031790A1 (it) | 2005-03-20 |
Family
ID=34362408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT001790A ITMI20031790A1 (it) | 2003-09-19 | 2003-09-19 | Antagonistici abiotici dell'eparina. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7465820B2 (it) |
| EP (1) | EP1663952B1 (it) |
| CN (1) | CN100390136C (it) |
| AT (1) | ATE397583T1 (it) |
| CA (1) | CA2539301A1 (it) |
| DE (1) | DE602004014285D1 (it) |
| IT (1) | ITMI20031790A1 (it) |
| WO (1) | WO2005028422A1 (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2289524A1 (en) * | 2001-03-08 | 2011-03-02 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers as anti-infective agents |
| CA2519023C (en) | 2003-03-17 | 2014-05-20 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers and oligomers and uses thereof |
| TWI388280B (zh) | 2004-01-23 | 2013-03-11 | Univ Pennsylvania | 面上兩性之聚芳基和聚芳炔基聚合物與寡聚物及其用途 |
| EP2301349A2 (en) * | 2005-02-25 | 2011-03-30 | The Trustees of The University of Pennsylvania | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer |
| WO2012162789A1 (en) * | 2011-06-01 | 2012-12-06 | University Of British Columbia | Polymers for reversing heparin-based anticoagulation |
| ITUB20160702A1 (it) * | 2016-02-12 | 2017-08-12 | Consiglio Nazionale Ricerche | Criogel per la rimozione di eparine ed eparinoidi da soluzioni acquose, fisiologiche e da fluidi biologici, suo processo di preparazione ed usi |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5409959A (en) | 1991-01-29 | 1995-04-25 | Genelabs Incorporated | Antithrombotic treatment with calix(n)arene compounds |
| JPH05264531A (ja) * | 1992-03-17 | 1993-10-12 | Showa Denko Kk | クロマトグラフィー用吸着担体 |
-
2003
- 2003-09-19 IT IT001790A patent/ITMI20031790A1/it unknown
-
2004
- 2004-09-16 AT AT04765261T patent/ATE397583T1/de not_active IP Right Cessation
- 2004-09-16 CN CNB2004800267604A patent/CN100390136C/zh not_active Expired - Fee Related
- 2004-09-16 CA CA002539301A patent/CA2539301A1/en not_active Abandoned
- 2004-09-16 WO PCT/EP2004/010358 patent/WO2005028422A1/en not_active Ceased
- 2004-09-16 US US10/572,387 patent/US7465820B2/en not_active Expired - Fee Related
- 2004-09-16 EP EP04765261A patent/EP1663952B1/en not_active Expired - Lifetime
- 2004-09-16 DE DE602004014285T patent/DE602004014285D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005028422A1 (en) | 2005-03-31 |
| CN100390136C (zh) | 2008-05-28 |
| CA2539301A1 (en) | 2005-03-31 |
| ATE397583T1 (de) | 2008-06-15 |
| EP1663952A1 (en) | 2006-06-07 |
| US7465820B2 (en) | 2008-12-16 |
| DE602004014285D1 (de) | 2008-07-17 |
| US20070082951A1 (en) | 2007-04-12 |
| CN1852890A (zh) | 2006-10-25 |
| EP1663952B1 (en) | 2008-06-04 |
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