ITMI20041222A1 - Procedimento perfezionato per la sintesi di bicalutamide - Google Patents

Procedimento perfezionato per la sintesi di bicalutamide

Info

Publication number: ITMI20041222A1
Authority: IT; Italy
Prior art keywords: bicalutamide; synthesis; fluorophenylthio; methyl; acyloxy
Prior art date: 2004-06-17

Application number

IT001222A

Other languages

English (en)

Inventor

Ernesto Landonio

Massimiliano Lussana

Enrica Pizzatti

Enrico Vigano'

Original Assignee

Cosma S P A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-17

Filing date

2004-06-17

Publication date

2004-09-17

2004-06-17 Application filed by Cosma S P A filed Critical Cosma S P A

2004-06-17 Priority to IT001222A priority Critical patent/ITMI20041222A1/it

2004-09-17 Publication of ITMI20041222A1 publication Critical patent/ITMI20041222A1/it

2005-05-24 Priority to DE602005015794T priority patent/DE602005015794D1/de

2005-05-24 Priority to EP05104384A priority patent/EP1614677B1/en

2005-05-24 Priority to US11/137,096 priority patent/US20060041161A1/en

2005-05-24 Priority to AT05104384T priority patent/ATE438619T1/de

Links

230000015572 biosynthetic process Effects 0.000 title abstract 3
LKJPYSCBVHEWIU-KRWDZBQOSA-N (R)-bicalutamide Chemical compound C([C@@](O)(C)C(=O)NC=1C=C(C(C#N)=CC=1)C(F)(F)F)S(=O)(=O)C1=CC=C(F)C=C1 LKJPYSCBVHEWIU-KRWDZBQOSA-N 0.000 title abstract 2
229960000997 bicalutamide Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000003786 synthesis reaction Methods 0.000 title abstract 2
ODIGIKRIUKFKHP-UHFFFAOYSA-N (n-propan-2-yloxycarbonylanilino) acetate Chemical compound CC(C)OC(=O)N(OC(C)=O)C1=CC=CC=C1 ODIGIKRIUKFKHP-UHFFFAOYSA-N 0.000 abstract 1
CTYJERNWLVBMTF-UHFFFAOYSA-N 3-(4-fluorophenyl)sulfanyl-2-hydroxy-2-methylpropanoic acid Chemical compound OC(=O)C(O)(C)CSC1=CC=C(F)C=C1 CTYJERNWLVBMTF-UHFFFAOYSA-N 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Lubricants (AREA)

IT001222A 2004-06-17 2004-06-17 Procedimento perfezionato per la sintesi di bicalutamide ITMI20041222A1 (it)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
IT001222A ITMI20041222A1 (it)	2004-06-17	2004-06-17	Procedimento perfezionato per la sintesi di bicalutamide
DE602005015794T DE602005015794D1 (de)	2004-06-17	2005-05-24	Verbessertes Verfahren zur Herstellung von Bicalutamid
EP05104384A EP1614677B1 (en)	2004-06-17	2005-05-24	Improved procedure for the synthesis of bicalutamide
US11/137,096 US20060041161A1 (en)	2004-06-17	2005-05-24	Procedure for the synthesis of bicalutamide
AT05104384T ATE438619T1 (de)	2004-06-17	2005-05-24	Verbessertes verfahren zur herstellung von bicalutamid

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT001222A ITMI20041222A1 (it)	2004-06-17	2004-06-17	Procedimento perfezionato per la sintesi di bicalutamide

Publications (1)

Publication Number	Publication Date
ITMI20041222A1 true ITMI20041222A1 (it)	2004-09-17

Family

ID=35004320

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT001222A ITMI20041222A1 (it)	2004-06-17	2004-06-17	Procedimento perfezionato per la sintesi di bicalutamide

Country Status (5)

Country	Link
US (1)	US20060041161A1 (it)
EP (1)	EP1614677B1 (it)
AT (1)	ATE438619T1 (it)
DE (1)	DE602005015794D1 (it)
IT (1)	ITMI20041222A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006103689A1 (en) *	2005-03-29	2006-10-05	Usv Limited	Process for preparation of bicalutamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE28864T1 (de)	1982-07-23	1987-08-15	Ici Plc	Amide-derivate.

2004
- 2004-06-17 IT IT001222A patent/ITMI20041222A1/it unknown
2005
- 2005-05-24 US US11/137,096 patent/US20060041161A1/en not_active Abandoned
- 2005-05-24 DE DE602005015794T patent/DE602005015794D1/de not_active Expired - Fee Related
- 2005-05-24 AT AT05104384T patent/ATE438619T1/de not_active IP Right Cessation
- 2005-05-24 EP EP05104384A patent/EP1614677B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE602005015794D1 (de)	2009-09-17
EP1614677A3 (en)	2006-02-01
ATE438619T1 (de)	2009-08-15
EP1614677A2 (en)	2006-01-11
EP1614677B1 (en)	2009-08-05
US20060041161A1 (en)	2006-02-23

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