ITMI20041255A1 - Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive - Google Patents

Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive

Info

Publication number
ITMI20041255A1
ITMI20041255A1 ITMI20041255A ITMI20041255A1 IT MI20041255 A1 ITMI20041255 A1 IT MI20041255A1 IT MI20041255 A ITMI20041255 A IT MI20041255A IT MI20041255 A1 ITMI20041255 A1 IT MI20041255A1
Authority
IT
Italy
Prior art keywords
oral administration
biologically active
active substances
microparticle systems
microparticle
Prior art date
Application number
Other languages
English (en)
Inventor
Ubaldo Conte
Massimo Faustini
Eleonora Munari
Mario Francesco Pace
Vincenzo Russo
Maria Luisa Torre
Daniele Vigo
Original Assignee
Univ Degli Studi Milano
Univ Pavia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano, Univ Pavia filed Critical Univ Degli Studi Milano
Priority to ITMI20041255 priority Critical patent/ITMI20041255A1/it
Publication of ITMI20041255A1 publication Critical patent/ITMI20041255A1/it
Priority to EP05760593A priority patent/EP1778192A2/en
Priority to PCT/IT2005/000353 priority patent/WO2005123034A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
ITMI20041255 2004-06-22 2004-06-22 Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive ITMI20041255A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI20041255 ITMI20041255A1 (it) 2004-06-22 2004-06-22 Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive
EP05760593A EP1778192A2 (en) 2004-06-22 2005-06-20 Microparticulate systems for the oral administration of biologically active substances
PCT/IT2005/000353 WO2005123034A2 (en) 2004-06-22 2005-06-20 Microparticulate systems for the oral administration of biologically active substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI20041255 ITMI20041255A1 (it) 2004-06-22 2004-06-22 Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive

Publications (1)

Publication Number Publication Date
ITMI20041255A1 true ITMI20041255A1 (it) 2004-09-22

Family

ID=35510243

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI20041255 ITMI20041255A1 (it) 2004-06-22 2004-06-22 Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive

Country Status (3)

Country Link
EP (1) EP1778192A2 (it)
IT (1) ITMI20041255A1 (it)
WO (1) WO2005123034A2 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008340304B2 (en) * 2007-12-21 2016-03-03 Aptevo Biotherapeutics Llc Stabilized factor IX formulations containing trehalose
JP5724108B2 (ja) 2009-04-22 2015-05-27 メドスキン ソリューションズ ドクター ズベラック アーゲーＭｅｄＳｋｉｎ Ｓｏｌｕｔｉｏｎｓ Ｄｒ．Ｓｕｗｅｌａｃｋ ＡＧ 凍結乾燥組成物
JP2014509846A (ja) 2011-02-18 2014-04-24 デュポン ニュートリション バイオサイエンシス エーピーエス 飼料添加用組成物
GB201102857D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
GB201102865D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
BR112015002449B1 (pt) 2012-08-03 2021-07-06 Dupont Nutrition Biosciences Aps composição aditiva para ração compreendendo pelo menos dois micro-organismos vivos alimentados diretamente (dfm) e método de aperfeiçoamento do desempenho gastrointestinal
GB201213801D0 (en) 2012-08-03 2012-09-12 Dupont Nutrition Biosci Aps Feed additive composition
US20160243154A1 (en) * 2013-10-23 2016-08-25 Donald W. Jessup Hyaluronic acid formulation
MX2018005759A (es) 2015-11-09 2018-08-01 Dupont Nutrition Biosci Aps Composicion de aditivo para piensos.
BR112018013082A2 (pt) 2015-12-29 2018-12-11 Intervet Int Bv vacina contra coccidiose
CN113115952A (zh) * 2021-05-27 2021-07-16 江苏恒康生物科技有限公司 一种含微晶球的耐胃酸爆珠及其制备方法
US11833224B1 (en) 2023-02-08 2023-12-05 Leuvian Llc Lyoprotectant compositions and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960011236B1 (ko) * 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형
US5230901A (en) * 1988-03-23 1993-07-27 Knoll Ag Sustained release tablet of a mixture of alginates and polyacrylates
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
US6251430B1 (en) * 1998-02-04 2001-06-26 Guohua Zhang Water insoluble polymer based sustained release formulation

Also Published As

Publication number Publication date
WO2005123034A8 (en) 2006-03-30
WO2005123034A2 (en) 2005-12-29
WO2005123034A3 (en) 2006-09-14
EP1778192A2 (en) 2007-05-02

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