ITMI20041965A1 - "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici" - Google Patents

"dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"

Info

Publication number
ITMI20041965A1
ITMI20041965A1 IT001965A ITMI20041965A ITMI20041965A1 IT MI20041965 A1 ITMI20041965 A1 IT MI20041965A1 IT 001965 A IT001965 A IT 001965A IT MI20041965 A ITMI20041965 A IT MI20041965A IT MI20041965 A1 ITMI20041965 A1 IT MI20041965A1
Authority
IT
Italy
Prior art keywords
p185neu
codifying
protein
dynamic
therapeutic uses
Prior art date
Application number
IT001965A
Other languages
English (en)
Inventor
Augusto Amici
Federica Cavallo
Guido Forni
Cristina Marchini
Elena Quaglino
Original Assignee
Augusto Amici
Federica Cavallo
Guido Forni
Cristina Marchini
Elena Quaglino
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Augusto Amici, Federica Cavallo, Guido Forni, Cristina Marchini, Elena Quaglino filed Critical Augusto Amici
Priority to IT001965A priority Critical patent/ITMI20041965A1/it
Publication of ITMI20041965A1 publication Critical patent/ITMI20041965A1/it
Priority to ES08004513T priority patent/ES2370540T3/es
Priority to US11/665,301 priority patent/US7985582B2/en
Priority to PT08004513T priority patent/PT1939217E/pt
Priority to ZA200703875A priority patent/ZA200703875B/xx
Priority to PCT/IB2005/003052 priority patent/WO2006040660A2/en
Priority to EP08004513A priority patent/EP1939217B1/en
Priority to AT08004513T priority patent/ATE524494T1/de
Priority to EP05795953A priority patent/EP1809668A2/en
Priority to KR1020077010630A priority patent/KR101337706B1/ko
Priority to CA2583499A priority patent/CA2583499C/en
Priority to SG200808639-9A priority patent/SG148195A1/en
Priority to RU2007117894/13A priority patent/RU2383620C2/ru
Priority to CNA2005800400573A priority patent/CN101065399A/zh
Priority to AU2005293218A priority patent/AU2005293218B2/en
Priority to SI200531425T priority patent/SI1939217T1/sl
Priority to DK08004513.1T priority patent/DK1939217T3/da
Priority to PL08004513T priority patent/PL1939217T3/pl
Priority to CN2010101923839A priority patent/CN101886090B/zh
Priority to JP2007536284A priority patent/JP5597346B2/ja
Priority to IL182510A priority patent/IL182510A0/en
Priority to NO20072457A priority patent/NO344353B1/no
Priority to HK11104573.4A priority patent/HK1150627B/xx
Priority to US13/173,339 priority patent/US8207141B2/en
Priority to HR20110729T priority patent/HRP20110729T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
IT001965A 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici" ITMI20041965A1 (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
IT001965A ITMI20041965A1 (it) 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"
JP2007536284A JP5597346B2 (ja) 2004-10-15 2005-10-13 ｐ１８５ｎｅｕタンパク質配列バリアントをコードするプラスミドおよびその治療的使用
CA2583499A CA2583499C (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
RU2007117894/13A RU2383620C2 (ru) 2004-10-15 2005-10-13 ПЛАЗМИДЫ, КОДИРУЮЩИЕ ВАРИАНТЫ ПОСЛЕДОВАТЕЛЬНОСТИ БЕЛКА p185neu, И ИХ ТЕРАПЕВТИЧЕСКОЕ ПРИМЕНЕНИЕ
PT08004513T PT1939217E (pt) 2004-10-15 2005-10-13 Plasmídeos que codificam para variantes de sequência da proteína p185neu e utilizações terapêuticas dos mesmos
ZA200703875A ZA200703875B (en) 2004-10-15 2005-10-13 Plasmids coding for P185NEU protein sequence variants and therapeutic uses thereof
PCT/IB2005/003052 WO2006040660A2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
EP08004513A EP1939217B1 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
AT08004513T ATE524494T1 (de) 2004-10-15 2005-10-13 Plasmid-kodierung für p185- proteinsequenzvarianten und therapeutische anwendungen davon
EP05795953A EP1809668A2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
KR1020077010630A KR101337706B1 (ko) 2004-10-15 2005-10-13 ｐ185ｎｅｕ 단백질 서열 변이체를 암호화하는플라스미드와 그의 치료 용도
ES08004513T ES2370540T3 (es) 2004-10-15 2005-10-13 Plásmidos que codifican para variantes de secuencia de la proteína p185neu y sus usos terapéuticos de los mismos.
SG200808639-9A SG148195A1 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
US11/665,301 US7985582B2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
CNA2005800400573A CN101065399A (zh) 2004-10-15 2005-10-13 编码p185neu蛋白质序列变体的质粒及其治疗用途
AU2005293218A AU2005293218B2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
SI200531425T SI1939217T1 (sl) 2004-10-15 2005-10-13 Plazmidi, ki kodirajo variante zaporedij proteina p185neu in terapevtske uporabe le-teh
DK08004513.1T DK1939217T3 (da) 2004-10-15 2005-10-13 Plasmider kodende for p185neu-proteinsekvensvarianter og terapeutiske anvendelser deraf
PL08004513T PL1939217T3 (pl) 2004-10-15 2005-10-13 Plazmidy kodujące warianty sekwencji białka p185neu i ich zastosowanie terapeutyczne
CN2010101923839A CN101886090B (zh) 2004-10-15 2005-10-13 编码p185neu蛋白质序列变体的质粒及其治疗用途
IL182510A IL182510A0 (en) 2004-10-15 2007-04-12 Plasmids coding for p185neu sequence variants and therapeutic uses thereof
NO20072457A NO344353B1 (no) 2004-10-15 2007-05-14 Plasmider som koder for p185neu proteinsekvensvarianter og terapeutisk anvendelse derav
HK11104573.4A HK1150627B (en) 2004-10-15 2011-05-09 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
US13/173,339 US8207141B2 (en) 2004-10-15 2011-06-30 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof
HR20110729T HRP20110729T1 (hr) 2004-10-15 2011-10-11 PLAZMIDI KOJI KODIRAJU VARIJANTE p185neu PROTEINSKE SEKVENCIJE I NJIHOVA TERAPIJSKA UPOTREBA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001965A ITMI20041965A1 (it) 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"

Publications (1)

Publication Number Publication Date
ITMI20041965A1 true ITMI20041965A1 (it) 2005-01-15

Family

ID=35539028

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001965A ITMI20041965A1 (it) 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"

Country Status (21)

Country Link
US (2) US7985582B2 (it)
EP (2) EP1809668A2 (it)
JP (1) JP5597346B2 (it)
KR (1) KR101337706B1 (it)
CN (2) CN101886090B (it)
AT (1) ATE524494T1 (it)
AU (1) AU2005293218B2 (it)
CA (1) CA2583499C (it)
DK (1) DK1939217T3 (it)
ES (1) ES2370540T3 (it)
HR (1) HRP20110729T1 (it)
IL (1) IL182510A0 (it)
IT (1) ITMI20041965A1 (it)
NO (1) NO344353B1 (it)
PL (1) PL1939217T3 (it)
PT (1) PT1939217E (it)
RU (1) RU2383620C2 (it)
SG (1) SG148195A1 (it)
SI (1) SI1939217T1 (it)
WO (1) WO2006040660A2 (it)
ZA (1) ZA200703875B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101638440B (zh) * 2008-07-29 2011-10-26 中国人民解放军军事医学科学院基础医学研究所 一种可诱发机体抗肿瘤免疫的异种抗原-Fc融合蛋白及其应用
EP2777711A1 (en) 2013-03-11 2014-09-17 Icon Genetics GmbH Her2/Neu cancer vaccine
WO2017184845A1 (en) * 2016-04-20 2017-10-26 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for rna or dna detection and sequencing

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY114769A (en) * 1994-04-18 2003-01-31 Aviron Inc Non-splicing variants of gp350/220
US5518885A (en) * 1994-04-19 1996-05-21 The United States Of America As Represented By The Department Of Health & Human Services ERBB2 promoter binding protein in neoplastic disease
US7794729B2 (en) * 1994-11-08 2010-09-14 The Trustees Of The University Of Pennsylvania Methods and compositions for immunotherapy of cancer
US7820180B2 (en) * 2004-09-24 2010-10-26 The Trustees Of The University Of Pennsylvania Listeria-based and LLO-based vaccines
HUP0105303A2 (en) * 1999-01-29 2002-05-29 Corixa Corp Her-2/neu fusion proteins
US20020177551A1 (en) * 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
AU2003286770A1 (en) * 2002-10-30 2004-06-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services METHODS FOR PROPHYLAXIS AND TREATMENT OF HER-2/neu TUMORS
DE10251520A1 (de) * 2002-11-04 2004-05-13 Valeo Wischersysteme Gmbh Adapter für ein Wischblatt
US20040253606A1 (en) * 2002-11-26 2004-12-16 Protein Design Labs, Inc. Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
ITMI20031942A1 (it) 2003-10-09 2005-04-10 Indena Spa Dna codificante p185^neu e suoi usi terapeutici

Also Published As

Publication number Publication date
US7985582B2 (en) 2011-07-26
EP1939217B1 (en) 2011-09-14
EP1939217A3 (en) 2008-09-03
JP2008516596A (ja) 2008-05-22
US20110256162A1 (en) 2011-10-20
AU2005293218B2 (en) 2011-11-17
CN101886090B (zh) 2012-09-26
CA2583499A1 (en) 2006-04-20
HK1150627A1 (en) 2012-01-06
DK1939217T3 (da) 2011-11-21
PT1939217E (pt) 2011-11-08
CA2583499C (en) 2013-12-03
SG148195A1 (en) 2008-12-31
PL1939217T3 (pl) 2012-02-29
ES2370540T3 (es) 2011-12-19
US20090214577A1 (en) 2009-08-27
AU2005293218A1 (en) 2006-04-20
CN101886090A (zh) 2010-11-17
US8207141B2 (en) 2012-06-26
WO2006040660A3 (en) 2006-06-15
IL182510A0 (en) 2007-09-20
ATE524494T1 (de) 2011-09-15
CN101065399A (zh) 2007-10-31
EP1939217A2 (en) 2008-07-02
KR101337706B1 (ko) 2013-12-06
NO20072457L (no) 2007-07-13
EP1809668A2 (en) 2007-07-25
ZA200703875B (en) 2008-08-27
NO344353B1 (no) 2019-11-11
RU2007117894A (ru) 2008-11-20
HRP20110729T1 (hr) 2011-11-30
SI1939217T1 (sl) 2012-01-31
WO2006040660A2 (en) 2006-04-20
KR20070085298A (ko) 2007-08-27
RU2383620C2 (ru) 2010-03-10
JP5597346B2 (ja) 2014-10-01

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