ITMI20042418A1 - Processo per la purificazione della gabapentina - Google Patents

Processo per la purificazione della gabapentina

Info

Publication number: ITMI20042418A1
Authority: IT; Italy
Prior art keywords: gabapentin; gabapentina; purification process; addition; relates
Prior art date: 2004-12-17

Application number

IT002418A

Other languages

English (en)

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-17

Filing date

2004-12-17

Publication date

2005-03-17

2004-12-17 Application filed by Zambon Spa filed Critical Zambon Spa

2004-12-17 Priority to IT002418A priority Critical patent/ITMI20042418A1/it

2005-03-17 Publication of ITMI20042418A1 publication Critical patent/ITMI20042418A1/it

2005-12-15 Priority to AT05823475T priority patent/ATE426591T1/de

2005-12-15 Priority to ES05823475T priority patent/ES2322086T3/es

2005-12-15 Priority to HR20090337T priority patent/HRP20090337T1/xx

2005-12-15 Priority to CA2590232A priority patent/CA2590232C/en

2005-12-15 Priority to EP05823475A priority patent/EP1841725B1/en

2005-12-15 Priority to PT05823475T priority patent/PT1841725E/pt

2005-12-15 Priority to JP2007546066A priority patent/JP5101296B2/ja

2005-12-15 Priority to US11/722,056 priority patent/US7989658B2/en

2005-12-15 Priority to SI200530651T priority patent/SI1841725T1/sl

2005-12-15 Priority to PCT/EP2005/056817 priority patent/WO2006064041A1/en

2005-12-15 Priority to DK05823475T priority patent/DK1841725T3/da

2005-12-15 Priority to DE602005013579T priority patent/DE602005013579D1/de

2007-06-07 Priority to IL183745A priority patent/IL183745A/en

2009-04-30 Priority to CY20091100478T priority patent/CY1109039T1/el

Links

UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 9
238000000746 purification Methods 0.000 title abstract 2
229960002870 gabapentin Drugs 0.000 abstract 4
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
230000001476 alcoholic effect Effects 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000007900 aqueous suspension Substances 0.000 abstract 1
150000003951 lactams Chemical class 0.000 abstract 1
239000002002 slurry Substances 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IT002418A 2004-12-17 2004-12-17 Processo per la purificazione della gabapentina ITMI20042418A1 (it)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
IT002418A ITMI20042418A1 (it)	2004-12-17	2004-12-17	Processo per la purificazione della gabapentina
DE602005013579T DE602005013579D1 (de)	2004-12-17	2005-12-15	Verfahren zur aufreinigung von gabapentin
PT05823475T PT1841725E (pt)	2004-12-17	2005-12-15	Processo para a purificação de gabapentina
US11/722,056 US7989658B2 (en)	2004-12-17	2005-12-15	Process for the purification of gabapentin
HR20090337T HRP20090337T1 (hr)	2004-12-17	2005-12-15	Postupak pročišćavanja gabapentina
CA2590232A CA2590232C (en)	2004-12-17	2005-12-15	A process for the purification of gabapentin
EP05823475A EP1841725B1 (en)	2004-12-17	2005-12-15	A process for the purification of gabapentin
AT05823475T ATE426591T1 (de)	2004-12-17	2005-12-15	Verfahren zur aufreinigung von gabapentin
JP2007546066A JP5101296B2 (ja)	2004-12-17	2005-12-15	ガバペンチンの精製プロセス
ES05823475T ES2322086T3 (es)	2004-12-17	2005-12-15	Un proceso para la purificacion de gabapentina.
SI200530651T SI1841725T1 (sl)	2004-12-17	2005-12-15	Proces za izolacijo gabapentina
PCT/EP2005/056817 WO2006064041A1 (en)	2004-12-17	2005-12-15	A process for the purification of gabapentin
DK05823475T DK1841725T3 (da)	2004-12-17	2005-12-15	Fremgangsmåde til oprensning af gabapentin
IL183745A IL183745A (en)	2004-12-17	2007-06-07	Process for the purification of gabapentin
CY20091100478T CY1109039T1 (el)	2004-12-17	2009-04-30	Μια διαδικασια για τον καθαρισμο γαβαπεντινης

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT002418A ITMI20042418A1 (it)	2004-12-17	2004-12-17	Processo per la purificazione della gabapentina

Publications (1)

Publication Number	Publication Date
ITMI20042418A1 true ITMI20042418A1 (it)	2005-03-17

Family

ID=36353861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT002418A ITMI20042418A1 (it)	2004-12-17	2004-12-17	Processo per la purificazione della gabapentina

Country Status (15)

Country	Link
US (1)	US7989658B2 (it)
EP (1)	EP1841725B1 (it)
JP (1)	JP5101296B2 (it)
AT (1)	ATE426591T1 (it)
CA (1)	CA2590232C (it)
CY (1)	CY1109039T1 (it)
DE (1)	DE602005013579D1 (it)
DK (1)	DK1841725T3 (it)
ES (1)	ES2322086T3 (it)
HR (1)	HRP20090337T1 (it)
IL (1)	IL183745A (it)
IT (1)	ITMI20042418A1 (it)
PT (1)	PT1841725E (it)
SI (1)	SI1841725T1 (it)
WO (1)	WO2006064041A1 (it)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4894476A (en) *	1988-05-02	1990-01-16	Warner-Lambert Company	Gabapentin monohydrate and a process for producing the same
IT1319234B1 (it) *	2000-10-23	2003-09-26	Zambon Spa	Processo di preparazione di gabapentina.
IT1319674B1 (it) *	2000-12-01	2003-10-23	Erregierre Spa	Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
US20040063994A1 (en) *	2001-03-16	2004-04-01	Paolo Rossi	Process for the preparation of cyclic amino acids
ITMI20012750A1 (it) *	2001-12-21	2003-06-21	Procos Spa	Processo per la produzione dell'acido 1-(amminometil)-cicloesil-acetico in forma pura
ITMI20022071A1 (it) *	2002-10-01	2004-04-02	Erregierre Spa	Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
WO2004093779A2 (en)	2003-04-21	2004-11-04	Matrix Laboratories Ltd	Process for the preparation of gabapentin form-ii
ITMI20031247A1 (it)	2003-06-20	2004-12-21	Zambon Spa	Processo per la purificazione di gabapentina
ITMI20032456A1 (it) *	2003-12-16	2005-06-17	Zambon Spa	Processo per la purificazione di gabapentina
ITMI20040579A1 (it) *	2004-03-25	2004-06-25	Zambon Spa	Processo di preparazione di gabapentina

2004
- 2004-12-17 IT IT002418A patent/ITMI20042418A1/it unknown
2005
- 2005-12-15 HR HR20090337T patent/HRP20090337T1/xx unknown
- 2005-12-15 EP EP05823475A patent/EP1841725B1/en not_active Expired - Lifetime
- 2005-12-15 WO PCT/EP2005/056817 patent/WO2006064041A1/en not_active Ceased
- 2005-12-15 SI SI200530651T patent/SI1841725T1/sl unknown
- 2005-12-15 CA CA2590232A patent/CA2590232C/en not_active Expired - Fee Related
- 2005-12-15 DE DE602005013579T patent/DE602005013579D1/de not_active Expired - Lifetime
- 2005-12-15 AT AT05823475T patent/ATE426591T1/de active
- 2005-12-15 DK DK05823475T patent/DK1841725T3/da active
- 2005-12-15 JP JP2007546066A patent/JP5101296B2/ja not_active Expired - Fee Related
- 2005-12-15 US US11/722,056 patent/US7989658B2/en not_active Expired - Fee Related
- 2005-12-15 PT PT05823475T patent/PT1841725E/pt unknown
- 2005-12-15 ES ES05823475T patent/ES2322086T3/es not_active Expired - Lifetime
2007
- 2007-06-07 IL IL183745A patent/IL183745A/en active IP Right Grant
2009
- 2009-04-30 CY CY20091100478T patent/CY1109039T1/el unknown

Also Published As

Publication number	Publication date
HRP20090337T1 (hr)	2009-07-31
EP1841725A1 (en)	2007-10-10
IL183745A (en)	2011-04-28
SI1841725T1 (sl)	2009-10-31
US20090292138A1 (en)	2009-11-26
EP1841725B1 (en)	2009-03-25
PT1841725E (pt)	2009-04-27
CA2590232C (en)	2013-02-12
JP2008524164A (ja)	2008-07-10
ATE426591T1 (de)	2009-04-15
IL183745A0 (en)	2007-09-20
CY1109039T1 (el)	2014-07-02
DE602005013579D1 (de)	2009-05-07
US7989658B2 (en)	2011-08-02
WO2006064041A1 (en)	2006-06-22
ES2322086T3 (es)	2009-06-16
DK1841725T3 (da)	2009-06-15
JP5101296B2 (ja)	2012-12-19
CA2590232A1 (en)	2006-06-22

Similar Documents

Publication	Publication Date	Title
BR112014015270A2 (pt)	2017-06-13	processo de preparação de sílica precipitada
EA201001444A1 (ru)	2011-04-29	Синтез эфиров или тиоэфиров адипата
BR112014015235A8 (pt)	2017-06-13	processo de preparação de sílicas
BR0209237A (pt)	2004-06-08	Processo para a preparação de uma solução de acrilamida aquosa com um biocatalisador
AU2003301508A1 (en)	2004-08-23	Processes for producing glutamic acid derivative and pyroglutamic acid derivative and novel intermediate for production
TW200635858A (en)	2006-10-16	Process to prepare salt
ITMI20042418A1 (it)	2005-03-17	Processo per la purificazione della gabapentina
UY29110A1 (es)	2006-04-28	Procedimiento de producción del polisacárido k5
PL1718673T3 (pl)	2008-03-31	Sposób oczyszczania albuminy obejmujący etap nanofiltracji, roztwór, i zawierająca go kompozycja do terapeutycznego zastosowania
HUP0300761A2 (hu)	2005-01-28	Eljárás amorf atorvasztatin-kalcium előállítására
MY146013A (en)	2012-06-15	Process for purifying mesotrione
ITMI20050466A1 (it)	2006-09-23	Processo di purificazione in acqua di acido tiottico
EA200501734A1 (ru)	2006-04-28	Способ получения (4-гидрокси-6-оксотетрагидропиран-2-ил)ацетонитрила и его производных
ATE373118T1 (de)	2007-09-15	Verfahren zur herstellung von peroxodisulfaten in wässriger lösung
TW200517368A (en)	2005-06-01	Process
EA201101324A1 (ru)	2012-06-29	Способ разделения платины (ii, iv) и родия (iii) в соляно-кислых водных растворах
TW200706951A (en)	2007-02-16	Emireflective display and method thereof
GB2418916A (en)	2006-04-12	Process for purifying citalopram using polybasic acids
ATE501145T1 (de)	2011-03-15	Narkotinreinigungsverfahren
BR0117040A (pt)	2004-07-27	Um composto inovador de esponja de sulfa de ferro poroso derivado de hematita
DE60310683D1 (de)	2007-02-08	Verfahren zur herstellung von 1-(mercaptomethyl)cyclopropan essigsäure
ATE444272T1 (de)	2009-10-15	Verfahren zur racematsspaltung von 3- aminopentannitril
BR0308485A (pt)	2005-01-18	Etano-1,2-diamìnio-bis[(2r)-2-bromo-3-fenilpropanoat o], processo para preparação do mesmo e uso do mesmo
NO20064484L (no)	2006-11-29	Isopropanol-vannopplosning av olanzapin
RU2008149446A (ru)	2010-06-20	Способ извлечения золота из кислых растворов