ITMI20071421A1 - Coltura per espandere cellule staminali ex-vivo - Google Patents

Coltura per espandere cellule staminali ex-vivo

Info

Publication number
ITMI20071421A1
ITMI20071421A1 IT001421A ITMI20071421A ITMI20071421A1 IT MI20071421 A1 ITMI20071421 A1 IT MI20071421A1 IT 001421 A IT001421 A IT 001421A IT MI20071421 A ITMI20071421 A IT MI20071421A IT MI20071421 A1 ITMI20071421 A1 IT MI20071421A1
Authority
IT
Italy
Prior art keywords
culture
expand
stem cells
live stem
live
Prior art date
Application number
IT001421A
Other languages
English (en)
Inventor
Rosaria Giordano
Lorenza Lazzari
Tiziana Montemurro
Paolo Rebulla
Girolamo Sirchia
Original Assignee
Fond Irccs Istituto Di Ricove
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fond Irccs Istituto Di Ricove filed Critical Fond Irccs Istituto Di Ricove
Priority to IT001421A priority Critical patent/ITMI20071421A1/it
Priority to MX2010000496A priority patent/MX2010000496A/es
Priority to RU2010105048/10A priority patent/RU2010105048A/ru
Priority to KR1020107002354A priority patent/KR20100040311A/ko
Priority to BRPI0814082-0A2A priority patent/BRPI0814082A2/pt
Priority to CA2693420A priority patent/CA2693420A1/en
Priority to US12/668,818 priority patent/US9206389B2/en
Priority to AU2008277391A priority patent/AU2008277391A1/en
Priority to JP2010516605A priority patent/JP2010533486A/ja
Priority to CN200880024832A priority patent/CN101743305A/zh
Priority to PCT/IB2008/001798 priority patent/WO2009010841A2/en
Priority to EP08788872A priority patent/EP2167646A2/en
Publication of ITMI20071421A1 publication Critical patent/ITMI20071421A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT001421A 2007-07-16 2007-07-16 Coltura per espandere cellule staminali ex-vivo ITMI20071421A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT001421A ITMI20071421A1 (it) 2007-07-16 2007-07-16 Coltura per espandere cellule staminali ex-vivo
MX2010000496A MX2010000496A (es) 2007-07-16 2008-07-09 Cultivo para expandir citoblastos ex-vivo.
RU2010105048/10A RU2010105048A (ru) 2007-07-16 2008-07-09 Культура для размножения стволовых клеток ex-vivo
KR1020107002354A KR20100040311A (ko) 2007-07-16 2008-07-09 생체 외에서의 줄기 세포 증식을 위한 배양액
BRPI0814082-0A2A BRPI0814082A2 (pt) 2007-07-16 2008-07-09 Cultura incluindo um meio de expansão e uma composição de citocinas, método para a expansão de células-tronco, células-tronco e uso de células
CA2693420A CA2693420A1 (en) 2007-07-16 2008-07-09 Culture for expanding stem cells ex-vivo
US12/668,818 US9206389B2 (en) 2007-07-16 2008-07-09 Culture for expanding stem cells ex-vivo
AU2008277391A AU2008277391A1 (en) 2007-07-16 2008-07-09 Culture for expanding stem cells ex-vivo
JP2010516605A JP2010533486A (ja) 2007-07-16 2008-07-09 幹細胞の生体外増殖培地
CN200880024832A CN101743305A (zh) 2007-07-16 2008-07-09 离体扩增干细胞的培养物
PCT/IB2008/001798 WO2009010841A2 (en) 2007-07-16 2008-07-09 Culture for expanding stem cells ex-vivo
EP08788872A EP2167646A2 (en) 2007-07-16 2008-07-09 Culture for expanding stem cells ex-vivo

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001421A ITMI20071421A1 (it) 2007-07-16 2007-07-16 Coltura per espandere cellule staminali ex-vivo

Publications (1)

Publication Number Publication Date
ITMI20071421A1 true ITMI20071421A1 (it) 2009-01-17

Family

ID=40202037

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001421A ITMI20071421A1 (it) 2007-07-16 2007-07-16 Coltura per espandere cellule staminali ex-vivo

Country Status (12)

Country Link
US (1) US9206389B2 (it)
EP (1) EP2167646A2 (it)
JP (1) JP2010533486A (it)
KR (1) KR20100040311A (it)
CN (1) CN101743305A (it)
AU (1) AU2008277391A1 (it)
BR (1) BRPI0814082A2 (it)
CA (1) CA2693420A1 (it)
IT (1) ITMI20071421A1 (it)
MX (1) MX2010000496A (it)
RU (1) RU2010105048A (it)
WO (1) WO2009010841A2 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods
CN108431211B (zh) 2015-10-20 2026-03-24 富士胶片细胞动力公司 通过遗传编程的多谱系造血前体细胞产生
EP3523422B1 (en) 2016-10-05 2024-12-25 FUJIFILM Cellular Dynamics, Inc. Generating mature lineages from induced pluripotent stem cells with mecp2 disruption
CN106754712B (zh) * 2016-11-21 2020-10-16 中国人民解放军军事医学科学院野战输血研究所 诱导脐带血单个核细胞分化为粒系细胞的方法
WO2018195175A1 (en) 2017-04-18 2018-10-25 FUJIFILM Cellular Dynamics, Inc. Antigen-specific immune effector cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2882992A (en) * 1991-11-06 1993-06-07 Arthur A. Axelrad Cell culture medium
JP2002529071A (ja) * 1998-11-09 2002-09-10 コンソルツィオ・ペール・ラ・ジェスティオーネ・デル・チェントロ・ディ・ビオテクノロジー・アヴァンツァテ 軟骨細胞様細胞のための無血清培地
US20060205071A1 (en) 2003-07-17 2006-09-14 Gamida-Cell Ltd. Methods for ex-vivo expanding stem/progenitor cells

Also Published As

Publication number Publication date
WO2009010841A3 (en) 2009-03-12
JP2010533486A (ja) 2010-10-28
BRPI0814082A2 (pt) 2014-10-07
CN101743305A (zh) 2010-06-16
MX2010000496A (es) 2010-04-27
KR20100040311A (ko) 2010-04-19
US9206389B2 (en) 2015-12-08
WO2009010841A2 (en) 2009-01-22
AU2008277391A1 (en) 2009-01-22
WO2009010841A8 (en) 2009-05-14
US20100189700A1 (en) 2010-07-29
CA2693420A1 (en) 2009-01-22
EP2167646A2 (en) 2010-03-31
RU2010105048A (ru) 2011-08-27

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