ITMI932012A0 - Procedimento per la preparazione di polimorfo i della terfenadina con distribuzione granulometrica ottimale - Google Patents
Procedimento per la preparazione di polimorfo i della terfenadina con distribuzione granulometrica ottimaleInfo
- Publication number
- ITMI932012A0 ITMI932012A0 IT93MI2012A ITMI932012A ITMI932012A0 IT MI932012 A0 ITMI932012 A0 IT MI932012A0 IT 93MI2012 A IT93MI2012 A IT 93MI2012A IT MI932012 A ITMI932012 A IT MI932012A IT MI932012 A0 ITMI932012 A0 IT MI932012A0
- Authority
- IT
- Italy
- Prior art keywords
- polymorpho
- terfenadine
- procedure
- preparation
- size distribution
- Prior art date
Links
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229960000351 terfenadine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI932012A IT1270829B (it) | 1993-09-17 | 1993-09-17 | Procedimento per la preparazione di polimorfo i della terfenadina con distribuzione granulometrica ottimale |
| PCT/EP1994/002390 WO1995007889A1 (en) | 1993-09-17 | 1994-07-20 | A process for the preparation of polymorph i of the terfenadine with an optimum granulometric distribution |
| AU72291/94A AU7229194A (en) | 1993-09-17 | 1994-07-20 | A process for the preparation of polymorph i of the terfenadine with an optimum granulometric distribution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI932012A IT1270829B (it) | 1993-09-17 | 1993-09-17 | Procedimento per la preparazione di polimorfo i della terfenadina con distribuzione granulometrica ottimale |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI932012A0 true ITMI932012A0 (it) | 1993-09-17 |
| ITMI932012A1 ITMI932012A1 (it) | 1995-03-17 |
| IT1270829B IT1270829B (it) | 1997-05-13 |
Family
ID=11366919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI932012A IT1270829B (it) | 1993-09-17 | 1993-09-17 | Procedimento per la preparazione di polimorfo i della terfenadina con distribuzione granulometrica ottimale |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU7229194A (it) |
| IT (1) | IT1270829B (it) |
| WO (1) | WO1995007889A1 (it) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4742175A (en) * | 1986-05-07 | 1988-05-03 | Merrell Dow Pharmaceuticals Inc. | Preparation of polymorphically pure terfenadine |
| IL93499A0 (en) * | 1989-02-28 | 1990-11-29 | Merrell Dow Pharma | Preparation of the low melting polymorphic form of terfenadine |
| CA2015390A1 (en) * | 1989-05-01 | 1990-11-01 | Frederick J. Mccarty | Process for the preparation of the high melting polymorphic of terfenadine |
| US5247092A (en) * | 1989-12-29 | 1993-09-21 | Erregierre Industria Chimica S.P.A. | Preparation of the high-melting polymorph of terfenadine |
| FR2681861B1 (fr) * | 1991-10-01 | 1995-06-09 | Isochem Sa | Procede de preparation d'une forme polymorphique de la terfenadine, a point de fusion eleve, d'une plus grande purete et produit obtenu. |
-
1993
- 1993-09-17 IT ITMI932012A patent/IT1270829B/it active IP Right Grant
-
1994
- 1994-07-20 WO PCT/EP1994/002390 patent/WO1995007889A1/en not_active Ceased
- 1994-07-20 AU AU72291/94A patent/AU7229194A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI932012A1 (it) | 1995-03-17 |
| IT1270829B (it) | 1997-05-13 |
| AU7229194A (en) | 1995-04-03 |
| WO1995007889A1 (en) | 1995-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |