ITRM20020115A0 - Espressione di enzimi lisosomiali in seme. - Google Patents

Espressione di enzimi lisosomiali in seme.

Info

Publication number
ITRM20020115A0
ITRM20020115A0 IT2002RM000115A ITRM20020115A ITRM20020115A0 IT RM20020115 A0 ITRM20020115 A0 IT RM20020115A0 IT 2002RM000115 A IT2002RM000115 A IT 2002RM000115A IT RM20020115 A ITRM20020115 A IT RM20020115A IT RM20020115 A0 ITRM20020115 A0 IT RM20020115A0
Authority
IT
Italy
Prior art keywords
seed
expression
lysosomial
enzymes
lysosomial enzymes
Prior art date
Application number
IT2002RM000115A
Other languages
English (en)
Inventor
Corrado Fogher
Serena Reggi
Original Assignee
Plantechno S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11456130&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ITRM20020115(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plantechno S R L filed Critical Plantechno S R L
Priority to IT2002RM000115A priority Critical patent/ITRM20020115A1/it
Publication of ITRM20020115A0 publication Critical patent/ITRM20020115A0/it
Priority to EP03712646A priority patent/EP1480510B1/en
Priority to DE60324773T priority patent/DE60324773D1/de
Priority to SI200331514T priority patent/SI1480510T1/sl
Priority to US10/506,448 priority patent/US20060031965A1/en
Priority to AT03712646T priority patent/ATE414418T1/de
Priority to PCT/IT2003/000120 priority patent/WO2003073839A2/en
Priority to AU2003217458A priority patent/AU2003217458A1/en
Publication of ITRM20020115A1 publication Critical patent/ITRM20020115A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2451—Glucanases acting on alpha-1,6-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT2002RM000115A 2002-03-01 2002-03-01 Espressione di enzimi lisosomiali in seme. ITRM20020115A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT2002RM000115A ITRM20020115A1 (it) 2002-03-01 2002-03-01 Espressione di enzimi lisosomiali in seme.
EP03712646A EP1480510B1 (en) 2002-03-01 2003-03-03 Expression of lysosomal enzymes in plant seeds
DE60324773T DE60324773D1 (de) 2002-03-01 2003-03-03 Expression von lysosomalen enzymen in pflanzensamen
SI200331514T SI1480510T1 (sl) 2002-03-01 2003-03-03 Izraĺ˝anje lizosomalnih encimov v rastlinskih semenih
US10/506,448 US20060031965A1 (en) 2002-03-01 2003-03-03 In- seed expression of lysosomal enzymes
AT03712646T ATE414418T1 (de) 2002-03-01 2003-03-03 Expression von lysosomalen enzymen in pflanzensamen
PCT/IT2003/000120 WO2003073839A2 (en) 2002-03-01 2003-03-03 Expression of lysosomal enzymes in plant seeds
AU2003217458A AU2003217458A1 (en) 2002-03-01 2003-03-03 Expression of lysosomal enzymes in plant seeds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002RM000115A ITRM20020115A1 (it) 2002-03-01 2002-03-01 Espressione di enzimi lisosomiali in seme.

Publications (2)

Publication Number Publication Date
ITRM20020115A0 true ITRM20020115A0 (it) 2002-03-01
ITRM20020115A1 ITRM20020115A1 (it) 2003-09-01

Family

ID=11456130

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002RM000115A ITRM20020115A1 (it) 2002-03-01 2002-03-01 Espressione di enzimi lisosomiali in seme.

Country Status (8)

Country Link
US (1) US20060031965A1 (it)
EP (1) EP1480510B1 (it)
AT (1) ATE414418T1 (it)
AU (1) AU2003217458A1 (it)
DE (1) DE60324773D1 (it)
IT (1) ITRM20020115A1 (it)
SI (1) SI1480510T1 (it)
WO (1) WO2003073839A2 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
JP2009501784A (ja) * 2005-07-18 2009-01-22 プロタリクス リミテッド 生物学的に活性な高分子の粘膜投与または経腸投与
ITRM20070129A1 (it) 2007-03-14 2008-09-15 Plantechno S R L Piante di tabacco mutagenizzate come coltura da seme per la produzioe di olio da usare ai fini energetici industriali e alimentari
EP2150608B1 (en) 2007-05-07 2017-11-29 Protalix Ltd. Large scale disposable bioreactor
ITUD20080055A1 (it) * 2008-03-13 2009-09-14 Transactiva S R L Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali
CA2917377A1 (en) * 2013-07-15 2015-01-22 New York University Methods and oral formulations for enzyme replacement therapy of human lysosomal and metabolic diseases
CN104164464A (zh) * 2014-08-26 2014-11-26 南昌大学 一种超声辅助酶解去糖基化制备低致敏大豆7s蛋白的方法
CN107429257B (zh) 2015-03-17 2022-02-15 艾丽法有限责任公司 糖基化溶酶体蛋白、生产方法和用途
WO2017088039A2 (en) * 2015-11-25 2017-06-01 Empresa Brasileira de Pesquisa Agropecuária A pest-resistant plant, a method of producing a pest-resistant plant, and nucleic acids for transforming a plant
EP3880830A4 (en) * 2018-11-16 2022-08-24 Asklepios Biopharmaceutical, Inc. VECTORS WITH A NUCLEIC ACID ENCODING LYSOSOMAL ENZYMES CONDENSED TO A LYSOSOMAL TARGETING SEQUENCE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6846968B1 (en) * 1988-02-26 2005-01-25 Large Scale Biology Corporation Production of lysosomal enzymes in plants by transient expression
US6288304B1 (en) * 1991-02-22 2001-09-11 Sembiosys Genetics Inc. Expression of somatotropin in plant seeds
AU7071196A (en) * 1995-09-14 1997-04-01 Croptech Development Corporation Production of lysosomal enzymes in plant-based expression systems
CA2305628C (en) * 1997-09-30 2008-08-26 The Regents Of The University Of California Production of proteins in plant seeds
IT1299565B1 (it) * 1998-07-17 2000-03-16 Plantechno S R L Polinucleotide sintetico codificante per la lattoferrina umana, vettori, cellule e piante transgeniche che lo contengono.

Also Published As

Publication number Publication date
US20060031965A1 (en) 2006-02-09
DE60324773D1 (de) 2009-01-02
WO2003073839A2 (en) 2003-09-12
ITRM20020115A1 (it) 2003-09-01
WO2003073839A3 (en) 2003-12-18
ATE414418T1 (de) 2008-12-15
AU2003217458A1 (en) 2003-09-16
WO2003073839A8 (en) 2004-09-10
AU2003217458A8 (en) 2003-09-16
EP1480510B1 (en) 2008-11-19
EP1480510A2 (en) 2004-12-01
SI1480510T1 (sl) 2009-04-30

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