ITRM20040318A1 - Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico. - Google Patents
Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico.Info
- Publication number
- ITRM20040318A1 ITRM20040318A1 IT000318A ITRM20040318A ITRM20040318A1 IT RM20040318 A1 ITRM20040318 A1 IT RM20040318A1 IT 000318 A IT000318 A IT 000318A IT RM20040318 A ITRM20040318 A IT RM20040318A IT RM20040318 A1 ITRM20040318 A1 IT RM20040318A1
- Authority
- IT
- Italy
- Prior art keywords
- biomedical
- beta
- alpha
- polyaspartyl
- hydrazide
- Prior art date
Links
- 239000000017 hydrogel Substances 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 2
- 229920002674 hyaluronan Polymers 0.000 abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract 2
- 238000010382 chemical cross-linking Methods 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 230000007515 enzymatic degradation Effects 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000318A ITRM20040318A1 (it) | 2004-06-28 | 2004-06-28 | Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico. |
| JP2007518813A JP2008504100A (ja) | 2004-06-28 | 2005-06-23 | ヒアルロン酸とアルファ,ベータ−ポリアスパラギン酸ヒドラジドとのヒドロゲル及びその生物医学的及び医薬的使用 |
| PCT/IT2005/000364 WO2006001046A1 (en) | 2004-06-28 | 2005-06-23 | Hydrogels of hyaluronic acid and alpha, beta-polyaspartylhydrazide and their biomedical and pharmaceutical uses |
| AT05760579T ATE387218T1 (de) | 2004-06-28 | 2005-06-23 | Hyaluronsäure und alpha-, beta- polyaspartylhydrazidhydrogele und deren biomedizinischen und pharmazeutischen anwendungen |
| DE602005005062T DE602005005062T2 (de) | 2004-06-28 | 2005-06-23 | Hyaluronsäure und alpha-, beta-polyaspartylhydrazidhydrogele und deren biomedizinischen und pharmazeutischen anwendungen |
| DK05760579T DK1773399T3 (da) | 2004-06-28 | 2005-06-23 | Hydrogeler af hyaluronsyre og alfa,beta-polyaspartylhydrazid og deres biomedicinske og farmaceutiske anvendelser |
| AU2005257078A AU2005257078B2 (en) | 2004-06-28 | 2005-06-23 | Hydrogels of hyaluronic acid and alpha, beta-polyaspartylhydrazide and their biomedical and pharmaceutical uses |
| CA2572127A CA2572127C (en) | 2004-06-28 | 2005-06-23 | Hydrogels of hyaluronic acid and alpha, beta-polyaspartylhydrazide and their biomedical and pharmaceutical uses |
| KR1020067027380A KR20070043724A (ko) | 2004-06-28 | 2005-06-23 | 히알루론산과 알파,베타-폴리아스파틸하이드라지드의하이드로겔 및 생물의학 분야와 제약 분야에서 이들의 용도 |
| EP05760579A EP1773399B1 (en) | 2004-06-28 | 2005-06-23 | Hydrogels of hyaluronic acid and alpha, beta-polyaspartylhydrazide and their biomedical and pharmaceutical uses |
| ES05760579T ES2303258T3 (es) | 2004-06-28 | 2005-06-23 | Hidrogeles de acido hialuronico y alfa,beta-poliaspartilhidracida y sus utilizaciones biomedicas y farmaceuticas. |
| PT05760579T PT1773399E (pt) | 2004-06-28 | 2005-06-23 | Hidrogéis de ácido hialurónico e alfa, beta-poliaspartilhidrazida e as suas utilizações biomédicas e farmacêuticas |
| US11/630,985 US20080292664A1 (en) | 2004-06-28 | 2005-06-23 | Hydrogels and Hyaluronic Acid and Alpha, Beta-Polyaspartyl-Hydrazide and Their Biomedical and Pharmaceutical Uses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000318A ITRM20040318A1 (it) | 2004-06-28 | 2004-06-28 | Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITRM20040318A1 true ITRM20040318A1 (it) | 2004-09-28 |
Family
ID=34981530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000318A ITRM20040318A1 (it) | 2004-06-28 | 2004-06-28 | Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080292664A1 (it) |
| EP (1) | EP1773399B1 (it) |
| JP (1) | JP2008504100A (it) |
| KR (1) | KR20070043724A (it) |
| AT (1) | ATE387218T1 (it) |
| AU (1) | AU2005257078B2 (it) |
| CA (1) | CA2572127C (it) |
| DE (1) | DE602005005062T2 (it) |
| DK (1) | DK1773399T3 (it) |
| ES (1) | ES2303258T3 (it) |
| IT (1) | ITRM20040318A1 (it) |
| PT (1) | PT1773399E (it) |
| WO (1) | WO2006001046A1 (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2623106C (en) | 2005-09-19 | 2013-12-24 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| EP2492285A1 (en) * | 2006-03-07 | 2012-08-29 | ProChon Biotech Ltd. | Hydrazido derivatives of hyaluronic acid |
| WO2009108760A2 (en) | 2008-02-26 | 2009-09-03 | Board Of Regents, The University Of Texas System | Dendritic macroporous hydrogels prepared by crystal templating |
| WO2009134344A1 (en) | 2008-04-28 | 2009-11-05 | Surmodics, Inc. | POLY-α(1→4)GLUCOPYRANOSE-BASED MATRICES WITH HYDRAZIDE CROSSLINKING |
| CZ301555B6 (cs) | 2008-11-06 | 2010-04-14 | Cpn S. R. O. | Zpusob prípravy DTPA sítovaných derivátu kyseliny hyaluronové a jejich modifikace |
| EP2213315A1 (en) | 2009-01-30 | 2010-08-04 | Mero S.r.L. | Antibacterial hydrogel and use thereof in orthopedics |
| IT1401498B1 (it) | 2010-07-30 | 2013-07-26 | Mero Srl | Idrogelo a base di acido ialuronico e suo uso in ortopedia |
| WO2012048283A1 (en) | 2010-10-08 | 2012-04-12 | Board Of Regents, The University Of Texas System | One-step processing of hydrogels for mechanically robust and chemically desired features |
| JP6042815B2 (ja) | 2010-10-08 | 2016-12-14 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム | 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜 |
| US11565027B2 (en) | 2012-12-11 | 2023-01-31 | Board Of Regents, The University Of Texas System | Hydrogel membrane for adhesion prevention |
| EP2931327B1 (en) | 2012-12-11 | 2019-02-13 | Board Of Regents, The University Of Texas System | Hydrogel membrane for adhesion prevention |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| US20180291123A1 (en) * | 2015-09-04 | 2018-10-11 | The Broad Of Regents Of The University Of Texas System | Di-functionalized hyaluronic acid derivatives and hydrogels thereof |
| KR101872222B1 (ko) * | 2016-08-02 | 2018-06-28 | 한림대학교 산학협력단 | 미소막 간격체 및 미소막 간격체-유착방지제 혼합물 |
| WO2018165327A1 (en) | 2017-03-08 | 2018-09-13 | Alafair Biosciences, Inc. | Hydrogel medium for the storage and preservation of tissue |
| CN115957373A (zh) * | 2022-12-29 | 2023-04-14 | 陕西科技大学 | 一种自溶性降解的可注射聚氨基酸水凝胶及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5616568A (en) * | 1993-11-30 | 1997-04-01 | The Research Foundation Of State University Of New York | Functionalized derivatives of hyaluronic acid |
| WO2002041877A1 (en) * | 2000-10-24 | 2002-05-30 | Clear Solutions Biotech, Inc. | Sodium hyaluronate microspheres |
| WO2005056608A1 (en) * | 2003-12-04 | 2005-06-23 | University Of Utah Research Foundation | Modified macromolecules and methods of making and using thereof |
-
2004
- 2004-06-28 IT IT000318A patent/ITRM20040318A1/it unknown
-
2005
- 2005-06-23 WO PCT/IT2005/000364 patent/WO2006001046A1/en not_active Ceased
- 2005-06-23 JP JP2007518813A patent/JP2008504100A/ja active Pending
- 2005-06-23 ES ES05760579T patent/ES2303258T3/es not_active Expired - Lifetime
- 2005-06-23 PT PT05760579T patent/PT1773399E/pt unknown
- 2005-06-23 DK DK05760579T patent/DK1773399T3/da active
- 2005-06-23 KR KR1020067027380A patent/KR20070043724A/ko not_active Withdrawn
- 2005-06-23 AU AU2005257078A patent/AU2005257078B2/en not_active Ceased
- 2005-06-23 US US11/630,985 patent/US20080292664A1/en not_active Abandoned
- 2005-06-23 EP EP05760579A patent/EP1773399B1/en not_active Expired - Lifetime
- 2005-06-23 DE DE602005005062T patent/DE602005005062T2/de not_active Expired - Lifetime
- 2005-06-23 CA CA2572127A patent/CA2572127C/en not_active Expired - Fee Related
- 2005-06-23 AT AT05760579T patent/ATE387218T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE387218T1 (de) | 2008-03-15 |
| KR20070043724A (ko) | 2007-04-25 |
| ES2303258T3 (es) | 2008-08-01 |
| AU2005257078B2 (en) | 2010-04-22 |
| JP2008504100A (ja) | 2008-02-14 |
| DE602005005062T2 (de) | 2008-12-04 |
| US20080292664A1 (en) | 2008-11-27 |
| AU2005257078A1 (en) | 2006-01-05 |
| DE602005005062D1 (de) | 2008-04-10 |
| PT1773399E (pt) | 2008-06-05 |
| EP1773399B1 (en) | 2008-02-27 |
| CA2572127A1 (en) | 2006-01-05 |
| CA2572127C (en) | 2013-02-05 |
| DK1773399T3 (da) | 2008-06-16 |
| WO2006001046A1 (en) | 2006-01-05 |
| EP1773399A1 (en) | 2007-04-18 |
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