ITRM20040586A1 - Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico. - Google Patents

Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico.

Info

Publication number
ITRM20040586A1
ITRM20040586A1 IT000586A ITRM20040586A ITRM20040586A1 IT RM20040586 A1 ITRM20040586 A1 IT RM20040586A1 IT 000586 A IT000586 A IT 000586A IT RM20040586 A ITRM20040586 A IT RM20040586A IT RM20040586 A1 ITRM20040586 A1 IT RM20040586A1
Authority
IT
Italy
Prior art keywords
interleuchina
medical field
antigenic epitopes
antibodies
relative
Prior art date
Application number
IT000586A
Other languages
English (en)
Inventor
Giovanni Monteleone
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Priority to IT000586A priority Critical patent/ITRM20040586A1/it
Publication of ITRM20040586A1 publication Critical patent/ITRM20040586A1/it
Priority to EA200701092A priority patent/EA200701092A1/ru
Priority to JP2007542522A priority patent/JP2008521797A/ja
Priority to CNA2005800406090A priority patent/CN101137664A/zh
Priority to KR1020077011462A priority patent/KR20070084407A/ko
Priority to EP05823947A priority patent/EP1817327A1/en
Priority to BRPI0516661-6A priority patent/BRPI0516661A/pt
Priority to MX2007006355A priority patent/MX2007006355A/es
Priority to PCT/IT2005/000691 priority patent/WO2006057027A1/en
Priority to CA002587889A priority patent/CA2587889A1/en
Priority to AU2005308411A priority patent/AU2005308411A1/en
Priority to US11/791,764 priority patent/US20090214549A1/en
Priority to IL183251A priority patent/IL183251A0/en
Priority to NO20073175A priority patent/NO20073175L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT000586A 2004-11-29 2004-11-29 Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico. ITRM20040586A1 (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT000586A ITRM20040586A1 (it) 2004-11-29 2004-11-29 Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico.
US11/791,764 US20090214549A1 (en) 2004-11-29 2005-11-24 Antigenic Epitopes Of Inteleukin-21, Related Antibodies And Their Use In Medical Field
BRPI0516661-6A BRPI0516661A (pt) 2004-11-29 2005-11-24 epitopos antigênicos da interleucina-21, anticorpos relacionados e seu uso no campo medicinal
JP2007542522A JP2008521797A (ja) 2004-11-29 2005-11-24 インターロイキン−２１の抗原性エピトープ、関連抗体及び医療分野におけるそれらの使用
CNA2005800406090A CN101137664A (zh) 2004-11-29 2005-11-24 白介素-21的抗原性表位，相关抗体以及它们在医学领域的应用
KR1020077011462A KR20070084407A (ko) 2004-11-29 2005-11-24 인터루킨-21의 항원성 에피토프, 관련된 항체 및 의료분야에서 이들의 용도
EP05823947A EP1817327A1 (en) 2004-11-29 2005-11-24 Antigenic epitopes of interleukin-21, related antibodies and their use in medical field
EA200701092A EA200701092A1 (ru) 2004-11-29 2005-11-24 Антигенные эпитопы интерлейкина-21, связанные с ними антитела и их применение в медицине
MX2007006355A MX2007006355A (es) 2004-11-29 2005-11-24 Epitopes antigenos de interleucina-21, anticuerpos relacionados y su uso en el campo medico.
PCT/IT2005/000691 WO2006057027A1 (en) 2004-11-29 2005-11-24 Antigenic epitopes of interleukin-21, related antibodies and their use in medical field
CA002587889A CA2587889A1 (en) 2004-11-29 2005-11-24 Antigenic epitopes of interleukin-21, related antibodies and their use in medical field
AU2005308411A AU2005308411A1 (en) 2004-11-29 2005-11-24 Antigenic epitopes of interleukin-21, related antibodies and their use in medical field
IL183251A IL183251A0 (en) 2004-11-29 2007-05-16 Antigenic epitopes of interleukin-21, related antibodies and heir use medical field
NO20073175A NO20073175L (no) 2004-11-29 2007-06-22 Antigene epitoper av interleukin-21, relaterte antistoffer og anvendelse derav innen det medisinske omradet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000586A ITRM20040586A1 (it) 2004-11-29 2004-11-29 Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico.

Publications (1)

Publication Number Publication Date
ITRM20040586A1 true ITRM20040586A1 (it) 2005-02-28

Family

ID=36013301

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000586A ITRM20040586A1 (it) 2004-11-29 2004-11-29 Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico.

Country Status (14)

Country Link
US (1) US20090214549A1 (it)
EP (1) EP1817327A1 (it)
JP (1) JP2008521797A (it)
KR (1) KR20070084407A (it)
CN (1) CN101137664A (it)
AU (1) AU2005308411A1 (it)
BR (1) BRPI0516661A (it)
CA (1) CA2587889A1 (it)
EA (1) EA200701092A1 (it)
IL (1) IL183251A0 (it)
IT (1) ITRM20040586A1 (it)
MX (1) MX2007006355A (it)
NO (1) NO20073175L (it)
WO (1) WO2006057027A1 (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009517406A (ja) 2005-11-28 2009-04-30 ザイモジェネティクス， インコーポレイテッド Ｉｌ−２１受容体アンタゴニスト
EP2805971A1 (en) 2005-11-28 2014-11-26 ZymoGenetics, Inc. IL-21 antagonists
US7943328B1 (en) 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
WO2009047360A1 (en) * 2007-10-11 2009-04-16 Novo Nordisk A/S Il-21 antibodies
EP3103813A1 (en) 2007-12-07 2016-12-14 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
WO2009132821A1 (en) * 2008-04-28 2009-11-05 Giuliani International Limited Interleukin (il-21) binding proteins and methods of making and using same
WO2012098113A1 (en) * 2011-01-17 2012-07-26 Novo Nordisk A/S Il-21 ligands
US20140170153A1 (en) * 2011-05-31 2014-06-19 Novo Nordisk A/S Il-21 epitope and il-21 ligands
EP3013858B1 (en) * 2013-06-27 2021-07-28 Monash University Il-21 binding proteins and uses thereof
AR099625A1 (es) * 2014-03-21 2016-08-03 Lilly Co Eli Anticuerpos de il-21
SI3128997T1 (sl) * 2014-04-08 2020-11-30 Boston Pharmaceuticals Inc. Vezavne molekule specifične za IL-21 in njihove uporabe
EP3233914A1 (en) * 2014-12-19 2017-10-25 Mabtech Ab Composition, kit and method for inhibition of il-21 mediated activation of human cells
EP3233120A4 (en) 2014-12-19 2018-05-30 Monash University Il-21 antibodies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2329274A1 (en) * 1998-05-29 1999-12-02 Steven M. Ruben Interleukin-21
US6307024B1 (en) * 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
MXPA04004167A (es) * 2001-11-05 2004-07-08 Zymogenetics Inc Antagonistas de interleucina-21.
WO2003087320A2 (en) * 2002-04-09 2003-10-23 Beth Israel Deaconess Medical Center, Inc. Antagonists of il-21 and modulation of il-21-mediated t cell responses
CA2529520A1 (en) * 2003-06-19 2004-12-29 Centocor, Inc. Interleukin-21 analogs

Also Published As

Publication number Publication date
EP1817327A1 (en) 2007-08-15
BRPI0516661A (pt) 2008-09-16
US20090214549A1 (en) 2009-08-27
CN101137664A (zh) 2008-03-05
JP2008521797A (ja) 2008-06-26
AU2005308411A1 (en) 2006-06-01
IL183251A0 (en) 2007-09-20
NO20073175L (no) 2007-08-23
KR20070084407A (ko) 2007-08-24
MX2007006355A (es) 2007-07-09
CA2587889A1 (en) 2006-06-01
WO2006057027A1 (en) 2006-06-01
EA200701092A1 (ru) 2008-02-28

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