ITRM20050103A1 - Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi. - Google Patents

Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi.

Info

Publication number
ITRM20050103A1
ITRM20050103A1 IT000103A ITRM20050103A ITRM20050103A1 IT RM20050103 A1 ITRM20050103 A1 IT RM20050103A1 IT 000103 A IT000103 A IT 000103A IT RM20050103 A ITRM20050103 A IT RM20050103A IT RM20050103 A1 ITRM20050103 A1 IT RM20050103A1
Authority
IT
Italy
Prior art keywords
interleuchine
antagonists
association
antiproliferative drugs
antiproliferative
Prior art date
Application number
IT000103A
Other languages
English (en)
Inventor
Rocco Savino
Pierfrancesco Tassone
Salvatore Venuta
Original Assignee
Rocco Savino
Pierfrancesco Tassone
Salvatore Venuta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rocco Savino, Pierfrancesco Tassone, Salvatore Venuta filed Critical Rocco Savino
Priority to IT000103A priority Critical patent/ITRM20050103A1/it
Priority to PCT/EP2006/060503 priority patent/WO2006094971A1/en
Priority to US11/908,022 priority patent/US20090035281A1/en
Priority to EP06708658A priority patent/EP1863533A1/en
Publication of ITRM20050103A1 publication Critical patent/ITRM20050103A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT000103A 2005-03-10 2005-03-10 Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi. ITRM20050103A1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT000103A ITRM20050103A1 (it) 2005-03-10 2005-03-10 Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi.
PCT/EP2006/060503 WO2006094971A1 (en) 2005-03-10 2006-03-07 Combination of interleukin-6 antagonists and antiproliferative drugs
US11/908,022 US20090035281A1 (en) 2005-03-10 2006-03-07 Combination of interleukin-6 antagonists and antiproliferative drugs
EP06708658A EP1863533A1 (en) 2005-03-10 2006-03-07 Combination of interleukin-6 antagonists and antiproliferative drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000103A ITRM20050103A1 (it) 2005-03-10 2005-03-10 Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi.

Publications (1)

Publication Number Publication Date
ITRM20050103A1 true ITRM20050103A1 (it) 2006-09-11

Family

ID=36649091

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000103A ITRM20050103A1 (it) 2005-03-10 2005-03-10 Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi.

Country Status (4)

Country Link
US (1) US20090035281A1 (it)
EP (1) EP1863533A1 (it)
IT (1) ITRM20050103A1 (it)
WO (1) WO2006094971A1 (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8252286B2 (en) 2007-05-21 2012-08-28 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8404235B2 (en) * 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
HUE032563T2 (en) 2007-05-21 2017-09-28 Alderbio Holdings Llc Antibodies to IL-6 and their use
EP2217258B1 (en) 2007-11-14 2014-03-26 General Regeneratives Limited Use of interleukin-1 receptor antagonist as a myeloprotective agent
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
EP2464666B1 (en) 2009-07-15 2018-03-21 Eva Kovacs-Benke Combination of a human interleukin-6 antagonist and a human interleukin-6 receptor antagonist in therapy of tumour diseases
CN101690801B (zh) 2009-10-26 2012-08-01 上海交通大学 白细胞介素-1受体拮抗剂的用途及其药物组合物
WO2011066374A2 (en) 2009-11-24 2011-06-03 Alder Biopharmaceuticals, Inc. Antagonists of il-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
US9304134B2 (en) 2010-11-23 2016-04-05 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of anemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276555B1 (it) * 1995-04-28 1997-11-03 Angeletti P Ist Richerche Bio Antagonisti di interluchina-6 umana del tutto incapaci di formare un legame con gp 130, e loro uso per la preparazione di composizioni
IT1291932B1 (it) * 1997-06-20 1999-01-21 Angeletti P Ist Richerche Bio Composizioni farmaceutiche antitumorali capaci anche di ridurre la farmacoresistenza in cellule tumorali, in particolare di carcinoma
WO2004071404A2 (en) * 2003-02-04 2004-08-26 Centocor Inc. Use of il-6 antagonists in combination with steroids to enhance apoptosis
US20050043233A1 (en) * 2003-04-29 2005-02-24 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis

Also Published As

Publication number Publication date
EP1863533A1 (en) 2007-12-12
WO2006094971A1 (en) 2006-09-14
US20090035281A1 (en) 2009-02-05

Similar Documents

Publication Publication Date Title
ITRM20050103A1 (it) Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi.
IS7894A (is) Skammtaform með ofnæmisvaka
FR2855756B1 (fr) Comprime orodispersible multicouche
DE602004021904D1 (de) Gyraseinhibitoren und deren verwendungen
DE602005020310D1 (de) Lanzette, lanzettenanordnung und lanzette-sensor-kombination
NL1025404A1 (nl) Pyrazolo-triazine verbindingen en gebruik daarvan.
DK1575618T3 (da) Dispergerbare farmaceutiske kombinationer
ATE506362T1 (de) 1-aza-bicycloä3.3.1ünonane
DE602004021477D1 (de) Kondensierte heterocyclen und deren verwendungen
EP1878809A4 (en) WELDING MATERIAL OF AL-NI-B ALLOY AND ELEMENTSTRUCTURE THEREWITH
DE602005022995D1 (de) Arylsulfone und damit verbundene verwendungen
NL1031627A1 (nl) Acylaminobicyclische heteroaromatische verbindingen en toepassingen daarvan.
EP1812055A4 (en) ANTIGENS OF CHLAMYDIA AND APPLICATIONS OF SAID ANTIGENS
ATE420118T1 (de) Biotinylierte hexadecasaccharide, pharmazeutische zusammensetzungen daraus und deren verwendung
NL1025908A1 (nl) Farmaceutische combinatie.
RU2004132147A (ru) Адаптоген
ES1051272Y (es) Peonza multiplicable.
NO20035096L (no) Konstantstromventil
ITRM20050619A1 (it) Dispositivo per la rappresentazione di strutture atomiche e molecolari.
ITRM20040183A1 (it) Miscela erboristica e fitofarmaco comprendente la stessa.
FI20050641A0 (fi) Telkimekanismi
FI6704U1 (fi) Runkotolppa
ITMO20050310A1 (it) La tavoletta dermopuntrice stimolante
ITMO20050026U1 (it) La tavoletta dermopuntrice stimolante
ITSV20040017A1 (it) La dama