ITRM20130138A1 - Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica - Google Patents
Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonicaInfo
- Publication number
- ITRM20130138A1 ITRM20130138A1 IT000138A ITRM20130138A ITRM20130138A1 IT RM20130138 A1 ITRM20130138 A1 IT RM20130138A1 IT 000138 A IT000138 A IT 000138A IT RM20130138 A ITRM20130138 A IT RM20130138A IT RM20130138 A1 ITRM20130138 A1 IT RM20130138A1
- Authority
- IT
- Italy
- Prior art keywords
- entitlely
- dive
- neighbor
- tied
- inhibitor
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/221—Echographic preparations; Ultrasonic imaging preparations characterised by the targeting agent or modifying agent linked to the acoustically-active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/225—Microparticles, microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0625—Warming the body, e.g. hyperthermia treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Ceramic Engineering (AREA)
- Nanotechnology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000138A ITRM20130138A1 (it) | 2013-03-07 | 2013-03-07 | Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica |
| PCT/IB2014/059490 WO2014136076A2 (en) | 2013-03-07 | 2014-03-06 | Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase |
| EP14714382.0A EP2964272A2 (en) | 2013-03-07 | 2014-03-06 | Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase |
| US14/773,046 US20160015661A1 (en) | 2013-03-07 | 2014-03-06 | Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000138A ITRM20130138A1 (it) | 2013-03-07 | 2013-03-07 | Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITRM20130138A1 true ITRM20130138A1 (it) | 2014-09-08 |
Family
ID=48227456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000138A ITRM20130138A1 (it) | 2013-03-07 | 2013-03-07 | Assemblato comprendente un assorbitore della luce nel vicino infrarosso legato covalentemente ad un inibitore dell'anidrasi carbonica |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160015661A1 (it) |
| EP (1) | EP2964272A2 (it) |
| IT (1) | ITRM20130138A1 (it) |
| WO (1) | WO2014136076A2 (it) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623657B (zh) * | 2014-12-25 | 2017-07-11 | 哈尔滨工程大学 | 一种应用于光动力治疗的纳米复合材料及其制备方法 |
| CN105535972B (zh) * | 2015-12-23 | 2018-10-16 | 中国科学院长春应用化学研究所 | 一种c3n4纳米复合材料、制备方法及其应用 |
| US10557854B2 (en) | 2016-03-16 | 2020-02-11 | On Target Laboratories, LLC | CA IX—NIR dyes and their uses |
| US12083187B2 (en) | 2017-12-29 | 2024-09-10 | Wayne State University | Method of treatment for solid tumors containing hypoxia and/or stroma features |
| CN108467469A (zh) * | 2018-01-24 | 2018-08-31 | 北京服装学院 | 一种光热转换聚氨酯储能薄膜材料及其制备方法和薄膜 |
| CN111166882B (zh) * | 2020-01-13 | 2021-09-07 | 山东大学 | 酞菁-rgd多肽-氧化石墨烯复合纳米材料及其制备方法与应用 |
| WO2023082212A1 (zh) * | 2021-11-13 | 2023-05-19 | 广东暨创硒源纳米研究院有限公司 | 硒化锡纳米粒子复合物及其对肿瘤相关巨噬细胞的应用 |
| CN117599214B (zh) * | 2023-11-29 | 2025-10-17 | 南京大学 | 一种靶向碳酸酐酶的顺铂诊疗探针及其制备方法与应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012154885A2 (en) * | 2011-05-09 | 2012-11-15 | Visen Medical, Inc. | Carbonic anhydrase targeting agents and methods of using same |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19600721A1 (de) | 1996-01-12 | 1997-07-17 | Hoechst Ag | Verwendung von Inhibitoren des Carboanhydratase (CAH) zum Herstellen eines Medikaments zur Behandlung von Krebs |
| SI2594265T1 (sl) | 2002-11-26 | 2016-03-31 | Institute Of Virology Slovak Academy Of Sciences | CA-IX specifični inhibitorji |
| NO20035681D0 (no) | 2003-12-18 | 2003-12-18 | Amersham Health As | Optisk avbildning av lungekreft |
| WO2007046893A2 (en) | 2005-10-19 | 2007-04-26 | Ibc Pharmaceuticals, Inc. | Methods for generating bioactive assemblies and uses thereof |
| WO2006137092A1 (en) | 2005-06-23 | 2006-12-28 | Supuran Claudiu T | Fluorescent sulfonamide derivatives having carbonic anhydrase inhibiting activity and their use as theapeutic and diagnostic agents |
| WO2008071421A1 (en) | 2006-12-15 | 2008-06-19 | Nicox S.A. | Nitrate esters of carbonic anhydrase inhibitors |
| US8227204B2 (en) | 2007-10-18 | 2012-07-24 | The Invention Science Fund I, Llc | Ionizing-radiation-responsive compositions, methods, and systems |
| CA2745972C (en) | 2008-12-16 | 2016-11-01 | Fundacio Privada Institut Catala De Nanotecnologia | Conjugates comprising nanoparticles coated with platinum containing compounds |
| EP2289528A1 (en) | 2009-07-21 | 2011-03-02 | DSM IP Assets B.V. | Novel nutraceutical compositions containing black pepper or its constituents improving mental performance |
| WO2011072133A1 (en) | 2009-12-09 | 2011-06-16 | William Marsh Rice University | Therapeutic compositions and methods for delivery of active agents cleavably linked to nanoparticles |
| CN103221388B (zh) | 2010-07-09 | 2016-09-28 | 维理生物技术公司 | 用于抑制转移性肿瘤生长的新型磺酰胺化合物 |
| CA2807274C (en) | 2010-08-02 | 2019-03-12 | University Of Houston | Interior functionalized hyperbranched dendron-conjugated nanoparticles and uses thereof |
| WO2012027493A1 (en) * | 2010-08-24 | 2012-03-01 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Molecular imaging of cancer cells in vivo |
| CA2856812A1 (en) | 2010-11-28 | 2012-05-31 | Metasignal Therapeutics Inc. | Carbonic anhydrase inhibitors with antimetastatic activity |
| WO2012175654A1 (en) | 2011-06-23 | 2012-12-27 | Facultes Universitaires Notre-Dame De La Paix | Tetraline sulfonamide derivatives for use in the treatment of proliferative disorders |
-
2013
- 2013-03-07 IT IT000138A patent/ITRM20130138A1/it unknown
-
2014
- 2014-03-06 US US14/773,046 patent/US20160015661A1/en not_active Abandoned
- 2014-03-06 EP EP14714382.0A patent/EP2964272A2/en not_active Withdrawn
- 2014-03-06 WO PCT/IB2014/059490 patent/WO2014136076A2/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012154885A2 (en) * | 2011-05-09 | 2012-11-15 | Visen Medical, Inc. | Carbonic anhydrase targeting agents and methods of using same |
Non-Patent Citations (4)
| Title |
|---|
| FULVIO RATTO ET AL: "Size and shape control in the overgrowth of gold nanorods", JOURNAL OF NANOPARTICLE RESEARCH ; AN INTERDISCIPLINARY FORUM FOR NANOSCALE SCIENCE AND TECHNOLOGY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 12, no. 6, 24 July 2009 (2009-07-24), pages 2029 - 2036, XP019826965, ISSN: 1572-896X * |
| KEVIN GROVES ET AL: "Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, GB, vol. 22, no. 1, 18 October 2011 (2011-10-18), pages 653 - 657, XP028352398, ISSN: 0960-894X, [retrieved on 20111024], DOI: 10.1016/J.BMCL.2011.10.058 * |
| MAAMAR STITI ET AL: "Carbonic Anhydrase Inhibitor Coated Gold Nanoparticles Selectively Inhibit the Tumor-Associated Isoform IX over the Cytosolic Isozymes I and II", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, no. 48, 3 December 2008 (2008-12-03), pages 16130 - 16131, XP055086710, ISSN: 0002-7863, DOI: 10.1021/ja805558k * |
| N. K. TAFRESHI ET AL: "Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes", CLINICAL CANCER RESEARCH, vol. 18, no. 1, 20 October 2011 (2011-10-20), pages 207 - 219, XP055086887, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-11-0238 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2964272A2 (en) | 2016-01-13 |
| US20160015661A1 (en) | 2016-01-21 |
| WO2014136076A3 (en) | 2014-11-20 |
| WO2014136076A2 (en) | 2014-09-12 |
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