ITRM990719A0 - Uso di ubichinone q10 per il trattamento locale e la prevenzione di patalogie aftalmologiche secondarie alla terapia fotorefrattiva, chirurg - Google Patents
Uso di ubichinone q10 per il trattamento locale e la prevenzione di patalogie aftalmologiche secondarie alla terapia fotorefrattiva, chirurgInfo
- Publication number
- ITRM990719A0 ITRM990719A0 IT1999RM000719A ITRM990719A ITRM990719A0 IT RM990719 A0 ITRM990719 A0 IT RM990719A0 IT 1999RM000719 A IT1999RM000719 A IT 1999RM000719A IT RM990719 A ITRM990719 A IT RM990719A IT RM990719 A0 ITRM990719 A0 IT RM990719A0
- Authority
- IT
- Italy
- Prior art keywords
- phthalmological
- ubiquinone
- surgery
- prevention
- local treatment
- Prior art date
Links
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 238000001356 surgical procedure Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999RM000719A IT1307281B1 (it) | 1999-11-25 | 1999-11-25 | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
| AT00974804T ATE251905T1 (de) | 1999-11-25 | 2000-10-30 | Verwendung von ubiquinon q 10 zur vorbeugung und behandlung von postoperativen okularen pathologien |
| EP00974804A EP1231909B1 (en) | 1999-11-25 | 2000-10-30 | Use of ubiquinone q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies |
| ES00974804T ES2208434T3 (es) | 1999-11-25 | 2000-10-30 | Uso de la ubiquinona q10 para un tratamiento local y para la prevencion de las patologias oftamologicas posquirurgicas. |
| AU13010/01A AU1301001A (en) | 1999-11-25 | 2000-10-30 | Use of ubiquinone q10 for a local treatment and prevention of ophthalmologic pathologies following photorefractive therapy, refractive surgery and exposure to ultraviolet radiation |
| PCT/IT2000/000434 WO2001037851A2 (en) | 1999-11-25 | 2000-10-30 | Use of ubiquinone q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies |
| DE60005992T DE60005992T2 (de) | 1999-11-25 | 2000-10-30 | Verwendung von ubiquinon q 10 zur vorbeugung und behandlung von postoperativen okularen pathologien |
| US09/901,320 US6787572B2 (en) | 1999-11-25 | 2001-07-09 | Use of ubiquinone Q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999RM000719A IT1307281B1 (it) | 1999-11-25 | 1999-11-25 | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM990719A0 true ITRM990719A0 (it) | 1999-11-25 |
| ITRM990719A1 ITRM990719A1 (it) | 2001-05-25 |
| IT1307281B1 IT1307281B1 (it) | 2001-10-30 |
Family
ID=11407065
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1999RM000719A IT1307281B1 (it) | 1999-11-25 | 1999-11-25 | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6787572B2 (it) |
| EP (1) | EP1231909B1 (it) |
| AT (1) | ATE251905T1 (it) |
| AU (1) | AU1301001A (it) |
| DE (1) | DE60005992T2 (it) |
| ES (1) | ES2208434T3 (it) |
| IT (1) | IT1307281B1 (it) |
| WO (1) | WO2001037851A2 (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20010755A1 (it) | 2001-12-20 | 2003-06-20 | Simonelli Giuseppe | Uso del chinone q10 per il trattamento delle malattie oculari. |
| DE60216612T2 (de) * | 2002-06-10 | 2007-09-20 | D.M.G. Italia S.R.L. | Carboxy Methyl Beta-1,3 Glucan enthaltende ophthalmische Lösung |
| ITRM20030153A1 (it) | 2003-04-03 | 2004-10-04 | Exall S R L | Formulazione idrosolubile contenente ubichinone per uso oftalmico. |
| CA2611914C (en) * | 2005-07-08 | 2013-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of a combination comprising l-carnitine or alkanoyl l-carnitine, lipid soluble benzoquinone and omega-3-polyunsaturated fatty acid for the preparation of a dietary supplement or medicament for the treatment of corneal diseases |
| EP3173068B1 (en) * | 2006-05-02 | 2020-09-09 | University of Miami | Topical co-enzyme q10 formulations and treatment of wounds |
| JP5673531B2 (ja) * | 2009-06-30 | 2015-02-18 | ライオン株式会社 | 眼科用組成物 |
| ITVA20100044A1 (it) * | 2010-05-20 | 2011-11-21 | Ciro Caruso | Soluzione oftalmica per proteggere strutture interne del globo oculare da raggi uv-a o per il trattamento del cheratocono con tecnica di cross-linking trans-epiteliale |
| US9192594B2 (en) * | 2009-07-27 | 2015-11-24 | Renato Sanseverino | Ophthalmic solution for protecting internal structures of the eyeball against UV-A rays or for the treatment of keratoconus with a trans-epithelial cross-linking technique |
| ES3017696T3 (en) | 2017-05-17 | 2025-05-13 | Bpgbio Inc | Use of coenzyme q10 formulations in the treatment and prevention of epidermolysis bullosa |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5947202A (ja) * | 1982-09-10 | 1984-03-16 | Zeria Shinyaku Kogyo Kk | 補酵素Q↓1↓0のメチル化−β−シクロデキストリン包接体及びその製造方法 |
| GB2301775B (en) * | 1995-06-07 | 1999-08-04 | Howard Foundation | Treatment of age-related macular degeneration with carotenoids |
| DE4410238A1 (de) * | 1994-03-25 | 1995-09-28 | Beiersdorf Ag | Hautpflegemittel |
| AU1145699A (en) * | 1997-09-05 | 1999-03-22 | Smithkline Beecham Biologicals (Sa) | Oil in water emulsions containing saponins |
| IT1304406B1 (it) * | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| WO2000057871A2 (en) * | 1999-03-30 | 2000-10-05 | Purdue Research Foundation | Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof |
-
1999
- 1999-11-25 IT IT1999RM000719A patent/IT1307281B1/it active
-
2000
- 2000-10-30 DE DE60005992T patent/DE60005992T2/de not_active Expired - Lifetime
- 2000-10-30 WO PCT/IT2000/000434 patent/WO2001037851A2/en not_active Ceased
- 2000-10-30 AU AU13010/01A patent/AU1301001A/en not_active Abandoned
- 2000-10-30 AT AT00974804T patent/ATE251905T1/de not_active IP Right Cessation
- 2000-10-30 ES ES00974804T patent/ES2208434T3/es not_active Expired - Lifetime
- 2000-10-30 EP EP00974804A patent/EP1231909B1/en not_active Expired - Lifetime
-
2001
- 2001-07-09 US US09/901,320 patent/US6787572B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1231909A2 (en) | 2002-08-21 |
| ATE251905T1 (de) | 2003-11-15 |
| DE60005992D1 (de) | 2003-11-20 |
| AU1301001A (en) | 2001-06-04 |
| ITRM990719A1 (it) | 2001-05-25 |
| IT1307281B1 (it) | 2001-10-30 |
| EP1231909B1 (en) | 2003-10-15 |
| US20030236239A1 (en) | 2003-12-25 |
| ES2208434T3 (es) | 2004-06-16 |
| WO2001037851A2 (en) | 2001-05-31 |
| WO2001037851A3 (en) | 2002-03-21 |
| US6787572B2 (en) | 2004-09-07 |
| DE60005992T2 (de) | 2004-07-22 |
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