ITTO20040343A1 - Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo - Google Patents

Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo

Info

Publication number: ITTO20040343A1
Authority: IT; Italy
Prior art keywords: neboglamine; neuropsychotic; neuroprotective; dimethylcyclohexyl; racemate
Prior art date: 2004-05-24

Application number

IT000343A

Other languages

English (en)

Inventor

Francesco Makovec

Lucio Claudio Rovati

Original Assignee

Rotta Res Lab Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-24

Filing date

2004-05-24

Publication date

2004-08-24

2004-05-24 Application filed by Rotta Res Lab Spa filed Critical Rotta Res Lab Spa

2004-05-24 Priority to IT000343A priority Critical patent/ITTO20040343A1/it

2004-08-24 Publication of ITTO20040343A1 publication Critical patent/ITTO20040343A1/it

2005-05-23 Priority to AT05747915T priority patent/ATE464042T1/de

2005-05-23 Priority to PT05747915T priority patent/PT1755583E/pt

2005-05-23 Priority to US11/569,545 priority patent/US7737180B2/en

2005-05-23 Priority to PCT/EP2005/052340 priority patent/WO2005115373A1/en

2005-05-23 Priority to DE602005020618T priority patent/DE602005020618D1/de

2005-05-23 Priority to AU2005247114A priority patent/AU2005247114B2/en

2005-05-23 Priority to JP2007513918A priority patent/JP4898666B2/ja

2005-05-23 Priority to DK05747915.6T priority patent/DK1755583T3/da

2005-05-23 Priority to ES05747915T priority patent/ES2340399T3/es

2005-05-23 Priority to EP05747915A priority patent/EP1755583B1/en

2005-05-23 Priority to CA2567397A priority patent/CA2567397C/en

2005-05-23 Priority to PL05747915T priority patent/PL1755583T3/pl

Links

VCRGLZYPNNAVRP-JTQLQIEISA-N (4s)-4-amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxopentanoic acid Chemical compound CC1(C)CCC(NC(=O)[C@@H](N)CCC(O)=O)CC1 VCRGLZYPNNAVRP-JTQLQIEISA-N 0.000 title abstract 5
229950007573 neboglamine Drugs 0.000 title abstract 2
230000000324 neuroprotective effect Effects 0.000 title 1
NTCVVGBUOCVHTI-AXDSSHIGSA-N (4s)-2-amino-4-[(4,4-dimethylcyclohexyl)amino]pentanedioic acid Chemical compound CC1(C)CCC(N[C@@H](CC(N)C(O)=O)C(O)=O)CC1 NTCVVGBUOCVHTI-AXDSSHIGSA-N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
201000000980 schizophrenia Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

IT000343A 2004-05-24 2004-05-24 Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo ITTO20040343A1 (it)

Priority Applications (13)

Application Number	Priority Date	Filing Date	Title
IT000343A ITTO20040343A1 (it)	2004-05-24	2004-05-24	Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo
PL05747915T PL1755583T3 (pl)	2004-05-24	2005-05-23	Zastosowanie neboglaminy do leczenia schizofrenii
PCT/EP2005/052340 WO2005115373A1 (en)	2004-05-24	2005-05-23	Use of neboglamine (cr 2249) as an antipsychotic and neuroprotective
PT05747915T PT1755583E (pt)	2004-05-24	2005-05-23	Uso de neboglamina (cr 2249) como um antipsicótico e neuroprotector
US11/569,545 US7737180B2 (en)	2004-05-24	2005-05-23	Use of neboglamine (CR 2249) as an antipsychotic and neuroprotective
AT05747915T ATE464042T1 (de)	2004-05-24	2005-05-23	Verwendung von neboglamine zur behandlung von schizophrenie
DE602005020618T DE602005020618D1 (de)	2004-05-24	2005-05-23	Verwendung von neboglamine zur behandlung von schizophrenie
AU2005247114A AU2005247114B2 (en)	2004-05-24	2005-05-23	Use of neboglamine (CR 2249) as an antipsychotic and neuroprotective
JP2007513918A JP4898666B2 (ja)	2004-05-24	2005-05-23	抗精神病薬および神経保護薬としてのネボグラミン（ｎｅｂｏｇｌａｍｉｎｅ）（ＣＲ２２４９）の使用
DK05747915.6T DK1755583T3 (da)	2004-05-24	2005-05-23	Anvendelse af neboglamin til behandling af skizofreni
ES05747915T ES2340399T3 (es)	2004-05-24	2005-05-23	Uso de neboglamina para el tratamiento de la esquizofrenia.
EP05747915A EP1755583B1 (en)	2004-05-24	2005-05-23	Use of neboglamine for the treatment of schizophrenia
CA2567397A CA2567397C (en)	2004-05-24	2005-05-23	Use of neboglamine (cr 2249) as an antipsychotic and neuroprotective

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT000343A ITTO20040343A1 (it)	2004-05-24	2004-05-24	Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo

Publications (1)

Publication Number	Publication Date
ITTO20040343A1 true ITTO20040343A1 (it)	2004-08-24

Family

ID=34968609

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT000343A ITTO20040343A1 (it)	2004-05-24	2004-05-24	Uso di neboglamine (cr2249) come neuropsicotico e neuroprotettivo

Country Status (13)

Country	Link
US (1)	US7737180B2 (it)
EP (1)	EP1755583B1 (it)
JP (1)	JP4898666B2 (it)
AT (1)	ATE464042T1 (it)
AU (1)	AU2005247114B2 (it)
CA (1)	CA2567397C (it)
DE (1)	DE602005020618D1 (it)
DK (1)	DK1755583T3 (it)
ES (1)	ES2340399T3 (it)
IT (1)	ITTO20040343A1 (it)
PL (1)	PL1755583T3 (it)
PT (1)	PT1755583E (it)
WO (1)	WO2005115373A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITTO20050691A1 (it)	2005-10-04	2007-04-05	Rottapharm Spa	Uso di neboglamine nella terapia delle tossicodipendenze

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1931927A1 (de) *	1968-07-06	1970-01-15	Yamanouchi Pharma Co Ltd	Neue Cyclohexylaminderivate
IT1264765B1 (it) *	1993-03-10	1996-10-04	Rotta Research Lab	Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la
AR037460A1 (es)	2001-11-30	2004-11-10	Smithkline Beecham Plc	Compuesto de hidroxietileno, composicion farmaceutica que lo comprende, uso del mismo para la fabricacion de un medicamento y procedimiento para su preparacion

2004
- 2004-05-24 IT IT000343A patent/ITTO20040343A1/it unknown
2005
- 2005-05-23 PT PT05747915T patent/PT1755583E/pt unknown
- 2005-05-23 DK DK05747915.6T patent/DK1755583T3/da active
- 2005-05-23 WO PCT/EP2005/052340 patent/WO2005115373A1/en not_active Ceased
- 2005-05-23 AU AU2005247114A patent/AU2005247114B2/en not_active Ceased
- 2005-05-23 PL PL05747915T patent/PL1755583T3/pl unknown
- 2005-05-23 AT AT05747915T patent/ATE464042T1/de active
- 2005-05-23 JP JP2007513918A patent/JP4898666B2/ja not_active Expired - Fee Related
- 2005-05-23 EP EP05747915A patent/EP1755583B1/en not_active Expired - Lifetime
- 2005-05-23 DE DE602005020618T patent/DE602005020618D1/de not_active Expired - Lifetime
- 2005-05-23 CA CA2567397A patent/CA2567397C/en not_active Expired - Fee Related
- 2005-05-23 US US11/569,545 patent/US7737180B2/en not_active Expired - Fee Related
- 2005-05-23 ES ES05747915T patent/ES2340399T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7737180B2 (en)	2010-06-15
CA2567397A1 (en)	2005-12-08
PT1755583E (pt)	2010-05-07
EP1755583A1 (en)	2007-02-28
DE602005020618D1 (de)	2010-05-27
CA2567397C (en)	2013-03-12
JP2008500309A (ja)	2008-01-10
EP1755583B1 (en)	2010-04-14
ES2340399T3 (es)	2010-06-02
ATE464042T1 (de)	2010-04-15
PL1755583T3 (pl)	2010-09-30
AU2005247114B2 (en)	2010-06-03
US20070249715A1 (en)	2007-10-25
AU2005247114A1 (en)	2005-12-08
WO2005115373A1 (en)	2005-12-08
DK1755583T3 (da)	2010-07-19
JP4898666B2 (ja)	2012-03-21

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