ITTO20060937A1 - Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi. - Google Patents

Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi.

Info

Publication number
ITTO20060937A1
ITTO20060937A1 IT000937A ITTO20060937A ITTO20060937A1 IT TO20060937 A1 ITTO20060937 A1 IT TO20060937A1 IT 000937 A IT000937 A IT 000937A IT TO20060937 A ITTO20060937 A IT TO20060937A IT TO20060937 A1 ITTO20060937 A1 IT TO20060937A1
Authority
IT
Italy
Prior art keywords
procedures
preparation
growth factors
cell line
cell lines
Prior art date
Application number
IT000937A
Other languages
English (en)
Inventor
Luisa Gennero
Gianfranco Merizzi
Giampiero Pescarmona
Antonio Ponzetto
Andrea Savarino
Original Assignee
Medestea Biotech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medestea Biotech S R L filed Critical Medestea Biotech S R L
Priority to IT000937A priority Critical patent/ITTO20060937A1/it
Priority to PCT/IB2007/055287 priority patent/WO2008081388A1/en
Priority to CN200780051926A priority patent/CN101679945A/zh
Priority to US12/521,517 priority patent/US20110045519A1/en
Priority to AT07859506T priority patent/ATE469210T1/de
Priority to EP07859506A priority patent/EP2102329B1/en
Priority to DE602007006844T priority patent/DE602007006844D1/de
Priority to ARP070105978A priority patent/AR064703A1/es
Publication of ITTO20060937A1 publication Critical patent/ITTO20060937A1/it

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/12—Hepatocyte growth factor [HGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/80—Neurotransmitters; Neurohormones
    • C12N2501/805—Acetylcholine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/30—Coculture with; Conditioned medium produced by tumour cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT000937A 2006-12-29 2006-12-29 Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi. ITTO20060937A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT000937A ITTO20060937A1 (it) 2006-12-29 2006-12-29 Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi.
PCT/IB2007/055287 WO2008081388A1 (en) 2006-12-29 2007-12-21 Differentiated immortalised cell lines capable of producing albumin and blood coagulation factors, methods of preparing thereof from a leukaemia cell line and uses thereof
CN200780051926A CN101679945A (zh) 2006-12-29 2007-12-21 能够产生白蛋白和凝血因子的已分化的无限增殖细胞系、从白血病细胞系制备该细胞系的方法及其用途
US12/521,517 US20110045519A1 (en) 2006-12-29 2007-12-21 Differentiated immortalised cell lines capable of producing albumin and blood coagulation factors, methods of preparing thereof from a leukaemia cell line and uses thereof
AT07859506T ATE469210T1 (de) 2006-12-29 2007-12-21 Differenzierte immortalisierte zelllinien mit fähigkeit zur produktion von albumin und blutgerinnungsfaktoren, verfahren zur herstellung davon aus einer leukämiezelllinie sowie verwendungen davon
EP07859506A EP2102329B1 (en) 2006-12-29 2007-12-21 Differentiated immortalised cell lines capable of producing albumin and blood coagulation factors, methods of preparing thereof from a leukaemia cell line and uses thereof
DE602007006844T DE602007006844D1 (de) 2006-12-29 2007-12-21 Differenzierte immortalisierte zelllinien mit fähigkeit zur produktion von albumin und blutgerinnungsfaktoren, verfahren zur herstellung davon aus einer leukämiezelllinie sowie verwendungen davon
ARP070105978A AR064703A1 (es) 2006-12-29 2007-12-28 Lineas celulares inmortales diferenciadas capaces de producir albumina y factores de coagulacion , procedimientos para su preparacion a partir de una linea celular leucemica y sus empleos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000937A ITTO20060937A1 (it) 2006-12-29 2006-12-29 Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi.

Publications (1)

Publication Number Publication Date
ITTO20060937A1 true ITTO20060937A1 (it) 2008-06-30

Family

ID=39332214

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000937A ITTO20060937A1 (it) 2006-12-29 2006-12-29 Linee cellulari immortali differenziate atte a produrre albumina e fattori di crescita, procedimenti per la loro preparazione da una linea cellulare leucemica e loro usi.

Country Status (8)

Country Link
US (1) US20110045519A1 (it)
EP (1) EP2102329B1 (it)
CN (1) CN101679945A (it)
AR (1) AR064703A1 (it)
AT (1) ATE469210T1 (it)
DE (1) DE602007006844D1 (it)
IT (1) ITTO20060937A1 (it)
WO (1) WO2008081388A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120295344A1 (en) * 2006-08-25 2012-11-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Stem Cell Fusion Model of Carcinogenesis
CN101851604B (zh) * 2010-04-20 2012-04-18 熊军 一种人血白蛋白的生产方法
CN107523537A (zh) * 2017-10-23 2017-12-29 洪丰 一种成体人肝源性干细胞系hn及其制备方法和应用
CN108330107B (zh) * 2018-04-24 2021-10-29 富恩生物技术（成都）有限公司 杂交瘤细胞株、cd68单克隆抗体、制备方法及应用
CN108753725A (zh) * 2018-05-23 2018-11-06 浙江大学 人血白蛋白高表达的人肝细胞系及其建立方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3117994B2 (ja) * 1990-05-16 2000-12-18 ベイラー・カレツジ・オブ・メデイシン 永久的ヒト肝細胞の細胞系および肝臓補助装置（ｌａｄ）におけるその使用
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
ITTO20050819A1 (it) * 2005-11-18 2007-05-19 Univ Degli Studi Torino Linea cellulare staminale pluripotente, linee cellulari derivate, procedimenti per la loro produzione e relativi usi

Also Published As

Publication number Publication date
WO2008081388A1 (en) 2008-07-10
US20110045519A1 (en) 2011-02-24
WO2008081388A8 (en) 2008-09-25
EP2102329B1 (en) 2010-05-26
CN101679945A (zh) 2010-03-24
AR064703A1 (es) 2009-04-22
ATE469210T1 (de) 2010-06-15
DE602007006844D1 (de) 2010-07-08
EP2102329A1 (en) 2009-09-23

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