ITTO910865A0 - Nuovi composti tricicli - Google Patents

Nuovi composti tricicli

Info

Publication number
ITTO910865A0
ITTO910865A0 IT91TO865A ITTO910865A ITTO910865A0 IT TO910865 A0 ITTO910865 A0 IT TO910865A0 IT 91TO865 A IT91TO865 A IT 91TO865A IT TO910865 A ITTO910865 A IT TO910865A IT TO910865 A0 ITTO910865 A0 IT TO910865A0
Authority
IT
Italy
Prior art keywords
tricycles
new compound
compound
new
compound tricycles
Prior art date
Application number
IT91TO865A
Other languages
English (en)
Inventor
Jacob Berger
Robin D Clark
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ITTO910865A0 publication Critical patent/ITTO910865A0/it
Publication of ITTO910865A1 publication Critical patent/ITTO910865A1/it
Application granted granted Critical
Publication of IT1250049B publication Critical patent/IT1250049B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ITTO910865A 1990-11-16 1991-11-12 Composti triciclici. IT1250049B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/614,326 US5189041A (en) 1990-11-16 1990-11-16 Tricyclic 5-ht3 receptor antagonists

Publications (3)

Publication Number Publication Date
ITTO910865A0 true ITTO910865A0 (it) 1991-11-12
ITTO910865A1 ITTO910865A1 (it) 1993-05-12
IT1250049B IT1250049B (it) 1995-03-30

Family

ID=24460766

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO910865A IT1250049B (it) 1990-11-16 1991-11-12 Composti triciclici.

Country Status (17)

Country Link
US (1) US5189041A (it)
EP (1) EP0485962A3 (it)
JP (1) JPH04283587A (it)
KR (1) KR920009828A (it)
AU (1) AU8785291A (it)
CA (1) CA2055680A1 (it)
FI (1) FI915400A7 (it)
HU (1) HUT59406A (it)
IE (1) IE913987A1 (it)
IL (1) IL100061A0 (it)
IT (1) IT1250049B (it)
MX (1) MX9102076A (it)
NO (1) NO914490L (it)
PL (1) PL292419A1 (it)
PT (1) PT99518A (it)
TW (1) TW208007B (it)
ZA (1) ZA919078B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL166267B1 (pl) * 1989-11-28 1995-04-28 Syntex Inc Sposób wytwarzania nowych zwiazków trójpierscieniowych PL PL PL PL
WO1993018036A1 (en) * 1992-03-12 1993-09-16 Smithkline Beecham Plc Condensed indole derivatives as 5ht4-receptor antagonists
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
ATE161819T1 (de) * 1993-04-27 1998-01-15 Solvay Fluor & Derivate Verfahren zur herstellung von carbonsäureestern aus carbonsäurehalogeniden und alkoholen
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
IT1303123B1 (it) 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
WO2001058869A2 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
EP1284732A2 (en) * 2000-05-18 2003-02-26 Glaxo Group Limited Method for treating functional dyspepsia using alosetron
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
MXPA04004373A (es) 2001-11-09 2004-08-11 Upjohn Co Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades.
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
MY143789A (en) 2003-02-18 2011-07-15 Helsinn Healthcare Sa Use of palonosetron treating post- operative nausea and vomiting
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
LT2889033T (lt) 2008-11-19 2018-07-10 Forum Pharmaceuticals Inc. Šizofrenijos negatyvių simptomų gydymas (r)-7-chlor-n-(chinuklidin-3-il)benzo[b]tiofen-2-karboksamidu ir jo farmaciniu požiūriu priimtinomis druskomis
US9145396B2 (en) * 2008-12-01 2015-09-29 Targacept, Inc. Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
PE20170923A1 (es) 2010-05-17 2017-07-12 Forum Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
EP3461481A1 (en) 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2121394A1 (fr) * 1971-01-08 1972-08-25 Anvar Procédé d'obtention de dérivés d'acides indole carboxyliques et produits préparables par ce procédé.
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
FR2475394A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Compositions pharmaceutiques contenant l'hexahydro-1, 2, 3, 3a, 4, 5, 6h indolo (3, 2, 1 - d. e) (1, 5) naphtyridinone - 6
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
US4948803A (en) * 1986-11-21 1990-08-14 Glaxo Group Limited Medicaments for treatment on prevention of withdrawal syndrome
EP0306323B1 (en) * 1987-09-03 1994-09-21 Glaxo Group Limited Lactam derivatives
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
JPH02167280A (ja) * 1988-08-15 1990-06-27 Glaxo Group Ltd ラクタム誘導体
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
EP0392663A1 (en) * 1989-03-13 1990-10-17 Ono Pharmaceutical Co., Ltd. Carboline derivative as a 5-HT3 receptor antagonist
JPH02290878A (ja) * 1989-04-28 1990-11-30 Ono Pharmaceut Co Ltd ベンゾチエノ（フロ）ピリジン誘導体

Also Published As

Publication number Publication date
IE913987A1 (en) 1992-05-20
ITTO910865A1 (it) 1993-05-12
EP0485962A3 (en) 1992-07-29
IL100061A0 (en) 1992-08-18
TW208007B (it) 1993-06-21
CA2055680A1 (en) 1992-05-17
MX9102076A (es) 1992-07-08
NO914490L (no) 1992-05-18
ZA919078B (en) 1993-05-17
AU8785291A (en) 1992-05-21
NO914490D0 (no) 1991-11-15
IT1250049B (it) 1995-03-30
HUT59406A (en) 1992-05-28
FI915400A0 (fi) 1991-11-15
PT99518A (pt) 1992-09-30
JPH04283587A (ja) 1992-10-08
EP0485962A2 (en) 1992-05-20
KR920009828A (ko) 1992-06-25
FI915400A7 (fi) 1992-05-17
HU913579D0 (en) 1992-01-28
US5189041A (en) 1993-02-23
PL292419A1 (en) 1993-04-05

Similar Documents

Publication Publication Date Title
BR1100956A (pt) Composto
MX9100513A (es) Compuestos
DE69219922D1 (de) Motorrad
BR9509760A (pt) Composto
BR1101108A (pt) Composto
ITTO910865A0 (it) Nuovi composti tricicli
MX9100018A (es) Histidinas sustituidas
MX9100517A (es) Compuestos
KR930703294A (ko) 항알레르기성 화합물
MX9101501A (es) Compuestos novedosos
FI921711A0 (fi) Polkupyörä
FI925980A7 (fi) Bisheterocykliska foereningar
FI911351A7 (fi) Uusia 8-sulfamyylimetyleeni-2-aminotetraliineja
AT399874B (de) Dichloranilinverbindung
NO930791D0 (no) Substituerte tinnsilikatforbindelser
FI920668A7 (fi) Oksatsinobentsatsoliyhdisteet
FI903950A7 (fi) Uusi yhdiste
FI940890L (fi) Uusia yhdisteitä
FI943637A7 (fi) Aryylialkoksifenoksi-imidatsoliiniyhdisteitä
FI923487A7 (fi) A87689-yhdisteitä
BR1100710A (pt) Composto
NO925056D0 (no) Bisheterocyklisk forbindelse
IT9067825A0 (it) Motocicletta
NO914153D0 (no) Salpinne for sykkel
DK222090D0 (da) Cykelstel

Legal Events

Date Code Title Description
0001 Granted