ITTO990703A0 - Procedimento per la preparazione di prodotti intermedi nella sintesi di lisinopril. - Google Patents

Procedimento per la preparazione di prodotti intermedi nella sintesi di lisinopril.

Info

Publication number
ITTO990703A0
ITTO990703A0 IT99TO000703A ITTO990703A ITTO990703A0 IT TO990703 A0 ITTO990703 A0 IT TO990703A0 IT 99TO000703 A IT99TO000703 A IT 99TO000703A IT TO990703 A ITTO990703 A IT TO990703A IT TO990703 A0 ITTO990703 A0 IT TO990703A0
Authority
IT
Italy
Prior art keywords
lisinopril
synthesis
procedure
preparation
intermediate products
Prior art date
Application number
IT99TO000703A
Other languages
English (en)
Inventor
Barbara Galbiati
Tiziano Ferrario
Valeriano Merli
Original Assignee
P F C Italiana Srl Speciality
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by P F C Italiana Srl Speciality filed Critical P F C Italiana Srl Speciality
Priority to IT1999TO000703A priority Critical patent/IT1307265B1/it
Publication of ITTO990703A0 publication Critical patent/ITTO990703A0/it
Priority to PCT/EP2000/007743 priority patent/WO2001010851A1/en
Priority to AU72742/00A priority patent/AU7274200A/en
Publication of ITTO990703A1 publication Critical patent/ITTO990703A1/it
Application granted granted Critical
Publication of IT1307265B1 publication Critical patent/IT1307265B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Control Of Vending Devices And Auxiliary Devices For Vending Devices (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Table Devices Or Equipment (AREA)
IT1999TO000703A 1999-08-09 1999-08-09 Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril. IT1307265B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT1999TO000703A IT1307265B1 (it) 1999-08-09 1999-08-09 Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.
PCT/EP2000/007743 WO2001010851A1 (en) 1999-08-09 2000-08-09 Process for the preparation of lysine-carboxyanhydride intermediates in the synthesis of lisinopril
AU72742/00A AU7274200A (en) 1999-08-09 2000-08-09 Process for the preparation of lysine-carboxyanhydride intermediates in the synthesis of lisinopril

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999TO000703A IT1307265B1 (it) 1999-08-09 1999-08-09 Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.

Publications (3)

Publication Number Publication Date
ITTO990703A0 true ITTO990703A0 (it) 1999-08-09
ITTO990703A1 ITTO990703A1 (it) 2001-02-09
IT1307265B1 IT1307265B1 (it) 2001-10-30

Family

ID=11418023

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999TO000703A IT1307265B1 (it) 1999-08-09 1999-08-09 Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril.

Country Status (3)

Country Link
AU (1) AU7274200A (it)
IT (1) IT1307265B1 (it)
WO (1) WO2001010851A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0102252B1 (pt) 2001-04-10 2013-10-22 Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso
US20070093664A1 (en) * 2002-06-19 2007-04-26 Tuncer Aslan Process for the production of lisinopril

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019521A (en) * 1990-03-12 1991-05-28 Photest Diagnostics, Inc. Paired polypeptides
IT1299341B1 (it) * 1998-02-09 2000-03-16 Pfc Italiana Srl Processo per la produzione di alcossicarbonildipeptidi intermedi nella sintesi del lisinopril.

Also Published As

Publication number Publication date
WO2001010851B1 (en) 2001-06-21
ITTO990703A1 (it) 2001-02-09
IT1307265B1 (it) 2001-10-30
AU7274200A (en) 2001-03-05
WO2001010851A1 (en) 2001-02-15

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