ITUA20161850A1 - Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP - Google Patents

Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP

Info

Publication number
ITUA20161850A1
ITUA20161850A1 ITUA2016A001850A ITUA20161850A ITUA20161850A1 IT UA20161850 A1 ITUA20161850 A1 IT UA20161850A1 IT UA2016A001850 A ITUA2016A001850 A IT UA2016A001850A IT UA20161850 A ITUA20161850 A IT UA20161850A IT UA20161850 A1 ITUA20161850 A1 IT UA20161850A1
Authority
IT
Italy
Prior art keywords
phosphorylated
rkip
biological
quantitative evaluation
phosphorylated form
Prior art date
Application number
ITUA2016A001850A
Other languages
English (en)
Inventor
Massimo Papale
Original Assignee
Fluidia S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidia S R L filed Critical Fluidia S R L
Priority to ITUA2016A001850A priority Critical patent/ITUA20161850A1/it
Priority to US16/086,728 priority patent/US20190154691A1/en
Priority to JP2019501772A priority patent/JP2019511731A/ja
Priority to CA3018653A priority patent/CA3018653A1/en
Priority to BR112018069363-4A priority patent/BR112018069363A2/pt
Priority to RU2018136934A priority patent/RU2018136934A/ru
Priority to ES17721837T priority patent/ES2774107T3/es
Priority to CN201780028383.5A priority patent/CN109154612B/zh
Priority to AU2017238743A priority patent/AU2017238743A1/en
Priority to EP17721837.7A priority patent/EP3433617B1/en
Priority to PCT/IB2017/051628 priority patent/WO2017163179A1/en
Publication of ITUA20161850A1 publication Critical patent/ITUA20161850A1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4704—Inhibitors; Supressors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
ITUA2016A001850A 2016-03-21 2016-03-21 Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP ITUA20161850A1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ITUA2016A001850A ITUA20161850A1 (it) 2016-03-21 2016-03-21 Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP
US16/086,728 US20190154691A1 (en) 2016-03-21 2017-03-21 Method for quantitative assessment in biological sample of the phosphorylated and non-phosphorylated form of rkip
JP2019501772A JP2019511731A (ja) 2016-03-21 2017-03-21 生体試料中のリン酸化型ｒｋｉｐおよび非リン酸化型ｒｋｉｐの定量的評価のための方法
CA3018653A CA3018653A1 (en) 2016-03-21 2017-03-21 Method for quantitative assessment in biological sample of the phosphorylated and non-phosphorylated form of rkip
BR112018069363-4A BR112018069363A2 (pt) 2016-03-21 2017-03-21 método para avaliação quantitativa da amostra biológica da forma fosforilada e não-fosforilada da rkip
RU2018136934A RU2018136934A (ru) 2016-03-21 2017-03-21 Способ количественной оценки фосфорированной и нефосфорилированной формы rkip в биологическом образце
ES17721837T ES2774107T3 (es) 2016-03-21 2017-03-21 Método para la evaluación cuantitativa en una muestra biológica de la forma fosforilada y no fosforilada de RKIP
CN201780028383.5A CN109154612B (zh) 2016-03-21 2017-03-21 生物样品中磷酸化和非磷化形式的rkip的定量评估方法
AU2017238743A AU2017238743A1 (en) 2016-03-21 2017-03-21 Method for quantitative assessment in biological sample of the phosphorylated and non-phosphorylated form of RKIP
EP17721837.7A EP3433617B1 (en) 2016-03-21 2017-03-21 Method for quantitative assessment in biological sample of the phosphorylated and non-phosphorylated form of rkip
PCT/IB2017/051628 WO2017163179A1 (en) 2016-03-21 2017-03-21 Method for quantitative assessment in biological sample of the phosphorylated and non-phosphorylated form of rkip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A001850A ITUA20161850A1 (it) 2016-03-21 2016-03-21 Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP

Publications (1)

Publication Number Publication Date
ITUA20161850A1 true ITUA20161850A1 (it) 2017-09-21

Family

ID=56507660

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A001850A ITUA20161850A1 (it) 2016-03-21 2016-03-21 Metodo per la valutazione quantitativa in biologico, della forma fosforilata e non fosforilata di RKIP

Country Status (11)

Country Link
US (1) US20190154691A1 (it)
EP (1) EP3433617B1 (it)
JP (1) JP2019511731A (it)
CN (1) CN109154612B (it)
AU (1) AU2017238743A1 (it)
BR (1) BR112018069363A2 (it)
CA (1) CA3018653A1 (it)
ES (1) ES2774107T3 (it)
IT (1) ITUA20161850A1 (it)
RU (1) RU2018136934A (it)
WO (1) WO2017163179A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107703294B (zh) * 2017-10-12 2019-06-04 华派生物工程集团有限公司 一种用于检测鸡血清中cLHRH抗体效价的ELISA方法
CN112940117A (zh) * 2021-04-08 2021-06-11 江西农业大学 一种鸡pebp1基因多克隆抗体、制备方法及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018570A1 (en) * 1999-09-01 2004-01-29 Brown University Kinase inhibitors and methods of use in screening assays and modulation of cell proliferation and growth
WO2011058136A1 (en) * 2009-11-16 2011-05-19 F. Hoffmann-La Roche Ag Calibration reagent and uses thereof

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
US6419933B1 (en) * 1995-11-14 2002-07-16 Corixa Corporation Compounds and methods for the detection and prevention of T.cruzi infection
JP2009236908A (ja) * 2008-03-04 2009-10-15 Kazuhiro Imai 乳癌の診断及び治療法
KR101409263B1 (ko) * 2012-10-16 2014-07-02 바디텍메드 주식회사 서브패드를 구비한 측방유동 분석용 스트립 및 이에 사용되는 측방유동 분석용 카트리지
US20150080236A1 (en) * 2013-09-16 2015-03-19 Kuwait University Method of sub-classifying breast cancer tumors
EP3265488A1 (en) * 2015-03-06 2018-01-10 Leibniz - Institut Für Analytische Wissenschaften Rkip agonism in the treatment and prevention of heart failure

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018570A1 (en) * 1999-09-01 2004-01-29 Brown University Kinase inhibitors and methods of use in screening assays and modulation of cell proliferation and growth
WO2011058136A1 (en) * 2009-11-16 2011-05-19 F. Hoffmann-La Roche Ag Calibration reagent and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
AHRIM MOON ET AL: "Reduced expression of Raf-1 kinase inhibitory protein in renal cell carcinomaa: a significant prognostic marker", PATHOLOGY., vol. 44, no. 6, 2012, pages 534 - 539, XP055327018 *
BRIANNE HILL ET AL: "Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma", ONCOTARGET, vol. 5, no. 17, 2014, pages 7406 - 7419, XP055327032 *
JUNE ESCARA-WILKE ET AL: "Raf kinase inhibitor protein (RKIP) in cancer", CANCER AND METASTASIS REVIEWS, KLUWER ACADEMIC PUBLISHERS, DO, vol. 31, no. 3 - 4, 2012, pages 615 - 620, XP035124657 *
SAM CROSS-KNORR ET AL: "RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients", BMC CANCER, vol. 13, no. 1, 2013, pages 463, XP021163556 *
SARA HUERTA-YEPEZ ET AL: "Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival", BMC CANCER, vol. 11, no. 1, 2011, pages 259, XP021102371 *
SIWEI LI ET AL: "Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma", RADIATION ONCOLOGY, vol. 31, no. 5, 20 September 2016 (2016-09-20), pages 615, XP055327166 *
VENERA CARDILE ET AL: "Raf kinase inhibitor protein (RKIP) and phospho-RKIP expression in melanomas", ACTA HISTOCHEMICA, vol. 115, no. 8, 2013, pages 795 - 802, XP055327164 *

Also Published As

Publication number Publication date
CN109154612B (zh) 2022-03-01
WO2017163179A1 (en) 2017-09-28
BR112018069363A2 (pt) 2019-01-22
EP3433617B1 (en) 2019-12-11
EP3433617A1 (en) 2019-01-30
JP2019511731A (ja) 2019-04-25
RU2018136934A (ru) 2020-04-22
CA3018653A1 (en) 2017-09-28
ES2774107T3 (es) 2020-07-16
US20190154691A1 (en) 2019-05-23
RU2018136934A3 (it) 2020-04-22
CN109154612A (zh) 2019-01-04
AU2017238743A1 (en) 2018-10-04

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