JO1832B1 - Theraputic agents - Google Patents
Theraputic agentsInfo
- Publication number
- JO1832B1 JO1832B1 JO19951832A JOP19951832A JO1832B1 JO 1832 B1 JO1832 B1 JO 1832B1 JO 19951832 A JO19951832 A JO 19951832A JO P19951832 A JOP19951832 A JO P19951832A JO 1832 B1 JO1832 B1 JO 1832B1
- Authority
- JO
- Jordan
- Prior art keywords
- alkyl
- compounds
- optionally substituted
- hydrogen
- absent
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 101100490437 Mus musculus Acvrl1 gene Proteins 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 102100034111 Activin receptor type-1 Human genes 0.000 abstract 1
- 101000799140 Homo sapiens Activin receptor type-1 Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Compounds of formula I and pharmaceutically acceptable salts thereof in Which R1, R2 and R3 independently represent hydrogen, hydro halo, alkyl or alkoxy; ALK1 represents a C2_6 alkylene chain optionally substituted by one or more C1-2 alkyl groups; Y represents a piperidine ring which is attached through nitrogen to ALK1; R4 represents hydrogen or a C1_4 alkyl group; the broken line in --- represents a bond, or is absent arid the free valency on Y is taken up by hydrog and the free valency on CR4 is taken up by hydrogen or C1_4 alkyl group; ALK2 is absent or represents a C1_4 alkylene chain optionally substituted by one or more C1_2 alkyl groups; and R5 and R6 independently represent hydrogen, alkyl, phenyl, alkyl (optionally substituted) or R5 and R6 together with the nitrogen atom to which they are attached represent a saturated 3-7 membered heterocyclic ring (with a proviso); are disclosed Which are antlinflammatory. antiallergic and immunomoclulatory agents. Compositions containing these compounds and processes to prepare these compounds are also disclosed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO19951832A JO1832B1 (en) | 1995-02-20 | 1995-02-20 | Theraputic agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO19951832A JO1832B1 (en) | 1995-02-20 | 1995-02-20 | Theraputic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO1832B1 true JO1832B1 (en) | 1995-07-05 |
Family
ID=48306975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19951832A JO1832B1 (en) | 1995-02-20 | 1995-02-20 | Theraputic agents |
Country Status (1)
| Country | Link |
|---|---|
| JO (1) | JO1832B1 (en) |
-
1995
- 1995-02-20 JO JO19951832A patent/JO1832B1/en active
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