JO2082B1 - الحبيبات المشكلة للكلافولنيت و السواغ - Google Patents
الحبيبات المشكلة للكلافولنيت و السواغInfo
- Publication number
- JO2082B1 JO2082B1 JO19982082A JOP19982082A JO2082B1 JO 2082 B1 JO2082 B1 JO 2082B1 JO 19982082 A JO19982082 A JO 19982082A JO P19982082 A JOP19982082 A JO P19982082A JO 2082 B1 JO2082 B1 JO 2082B1
- Authority
- JO
- Jordan
- Prior art keywords
- granules
- clavulanate
- excipients
- employing
- prepare
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 2
- 229940090805 clavulanate Drugs 0.000 title abstract 2
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- 239000008187 granular material Substances 0.000 title abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
يوفر هذا الاختراع حبيبات كلافيولانيت تحتوي على سواغات خاملة للتشكيلات الصيدلانية أيضا طريقة اتحضير هذه الحبيبات باستخدام اداة تنخيل من المفضل أن تحتوي على نظام هوائي نفاث.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203576 | 1997-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2082B1 true JO2082B1 (ar) | 2000-05-21 |
Family
ID=8228930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19982082A JO2082B1 (ar) | 1997-11-17 | 1998-11-17 | الحبيبات المشكلة للكلافولنيت و السواغ |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0973520A1 (ar) |
| JP (1) | JP2001516365A (ar) |
| CN (1) | CN1242705A (ar) |
| AU (1) | AU1337999A (ar) |
| BR (1) | BR9806280A (ar) |
| CA (1) | CA2272402A1 (ar) |
| CO (1) | CO4980893A1 (ar) |
| JO (1) | JO2082B1 (ar) |
| NO (1) | NO993467L (ar) |
| PL (1) | PL334517A1 (ar) |
| TR (1) | TR199901584T1 (ar) |
| WO (1) | WO1999025343A1 (ar) |
| ZA (1) | ZA9810499B (ar) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294199B1 (en) | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
| US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
| US7250176B1 (en) | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
| US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
| EP1330236A2 (en) | 2000-10-12 | 2003-07-30 | Beecham Pharmaceuticals (Pte) Limited | Formulation containing amoxicillin |
| GB0031267D0 (en) * | 2000-12-21 | 2001-01-31 | Smithkline Beecham Plc | Novel compositions |
| AT412344B (de) * | 2001-04-12 | 2005-01-25 | Sandoz Ag | Hydrophobisierte teilchen von k-clavulanat |
| AT413983B (de) * | 2001-04-12 | 2006-08-15 | Sandoz Ag | K-clavulanat in der form eines granulates |
| AU2004234176B2 (en) * | 2003-05-02 | 2010-05-13 | Globopharm Pharmazeutische Produktions- Und Handelsgesellschaft M.B.H. | Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts |
| US8293272B2 (en) * | 2003-05-02 | 2012-10-23 | Globopharm Pharmazeutische Produktions-Und Handelsgesellschaft M.B.H. | Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts |
| FI20080352A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi |
| US8951562B2 (en) | 2006-11-10 | 2015-02-10 | Atacama Labs Oy | Method and apparatus or dry granulation |
| FI20080351A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi |
| FI20080346A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi lisäaineita sisältävän tabletin valmistamiseksi |
| FI20080353A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi erittäin korkean lääkepitoisuuden tabletin valmistamiseksi |
| FI20070521A7 (fi) | 2006-11-10 | 2008-05-11 | Atacama Labs Oy | Rakeita, tabletteja ja rakeistusmenetelmä |
| FI20080355A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi metforminia käsittävien tablettien valmistamiseksi |
| CA2723409C (en) | 2008-05-09 | 2016-11-08 | Atacama Labs Oy | Method and apparatus for dry granulation |
| CN104582692A (zh) * | 2012-08-28 | 2015-04-29 | 中化帝斯曼制药有限公司荷兰公司 | 包含抗生素和β-内酰胺酶抑制剂的组合物,其中抗生素和β-内酰胺酶抑制剂中的至少一种是迷你片剂的形式 |
| JP2014062064A (ja) * | 2012-09-21 | 2014-04-10 | Ohara Yakuhin Kogyo Kk | バルサルタン含有錠剤の製造方法 |
| JP6141472B2 (ja) * | 2016-03-02 | 2017-06-07 | 大原薬品工業株式会社 | バルサルタン含有錠剤の製造方法 |
| KR20250026366A (ko) * | 2017-07-05 | 2025-02-25 | 노파르티스 아게 | 신규한 약학적 조성물 |
| CN110051637A (zh) * | 2019-05-21 | 2019-07-26 | 葵花药业集团北京药物研究院有限公司 | 阿莫西林克拉维酸钾制剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2251250C3 (de) * | 1972-10-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten |
| NZ187013A (en) * | 1977-04-27 | 1985-04-30 | Beecham Group Ltd | 9-amino-9-deoxy-clavulanic acid derivatives and pharmaceutical compositions |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| DE3887179T2 (de) * | 1987-03-02 | 1994-06-16 | Brocades Pharma Bv | Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. |
| IL109770A0 (en) * | 1993-05-29 | 1994-11-28 | Smithkline Beecham Corp | Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby |
-
1998
- 1998-11-09 TR TR1999/01584T patent/TR199901584T1/xx unknown
- 1998-11-09 AU AU13379/99A patent/AU1337999A/en not_active Abandoned
- 1998-11-09 PL PL98334517A patent/PL334517A1/xx unknown
- 1998-11-09 CN CN98801549A patent/CN1242705A/zh active Pending
- 1998-11-09 CA CA002272402A patent/CA2272402A1/en not_active Abandoned
- 1998-11-09 WO PCT/EP1998/007225 patent/WO1999025343A1/en not_active Ceased
- 1998-11-09 EP EP98956907A patent/EP0973520A1/en not_active Withdrawn
- 1998-11-09 JP JP52751299A patent/JP2001516365A/ja active Pending
- 1998-11-09 BR BR9806280-8A patent/BR9806280A/pt not_active Application Discontinuation
- 1998-11-17 JO JO19982082A patent/JO2082B1/ar active
- 1998-11-17 ZA ZA9810499A patent/ZA9810499B/xx unknown
- 1998-11-17 CO CO98067517A patent/CO4980893A1/es unknown
-
1999
- 1999-07-14 NO NO993467A patent/NO993467L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1337999A (en) | 1999-06-07 |
| ZA9810499B (en) | 1999-05-24 |
| TR199901584T1 (xx) | 2000-01-21 |
| CO4980893A1 (es) | 2000-11-27 |
| PL334517A1 (en) | 2000-02-28 |
| WO1999025343A1 (en) | 1999-05-27 |
| JP2001516365A (ja) | 2001-09-25 |
| EP0973520A1 (en) | 2000-01-26 |
| NO993467D0 (no) | 1999-07-14 |
| BR9806280A (pt) | 2000-02-15 |
| CN1242705A (zh) | 2000-01-26 |
| CA2272402A1 (en) | 1999-05-27 |
| NO993467L (no) | 1999-07-14 |
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