JO2129B1 - Non Aqueous anthelmintic composition - Google Patents
Non Aqueous anthelmintic compositionInfo
- Publication number
- JO2129B1 JO2129B1 JO19992129A JOP19992129A JO2129B1 JO 2129 B1 JO2129 B1 JO 2129B1 JO 19992129 A JO19992129 A JO 19992129A JO P19992129 A JOP19992129 A JO P19992129A JO 2129 B1 JO2129 B1 JO 2129B1
- Authority
- JO
- Jordan
- Prior art keywords
- non aqueous
- anthelmintic composition
- composition
- anthelmintic
- milb
- Prior art date
Links
- 230000000507 anthelmentic effect Effects 0.000 title 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 abstract 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 abstract 1
- 239000005660 Abamectin Substances 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
- 244000078703 ectoparasite Species 0.000 abstract 1
- 244000079386 endoparasite Species 0.000 abstract 1
- 229940074076 glycerol formal Drugs 0.000 abstract 1
- 229960002418 ivermectin Drugs 0.000 abstract 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
- 230000000590 parasiticidal effect Effects 0.000 abstract 1
- 239000002297 parasiticide Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A veterinary composition, for combating endoparasites and ectoparasites, and offering an improved pharmacokinetic profile, contains as parasiticide an Avermectin, especially Ivermectin or a Milb emycin, in an amount of from about 0.1 %w/v to 20 %w/v, dissolved in a solvent system containing up to about 75 %v/v of polyethylene glycol and not less than about 25 %v/v glycerol formal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9816132.6A GB9816132D0 (en) | 1998-07-24 | 1998-07-24 | Non-aqueous anthelmintic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO2129B1 true JO2129B1 (en) | 2002-08-07 |
Family
ID=10836088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO19992129A JO2129B1 (en) | 1998-07-24 | 1999-07-20 | Non Aqueous anthelmintic composition |
Country Status (9)
| Country | Link |
|---|---|
| AR (1) | AR020613A1 (en) |
| AU (1) | AU5054099A (en) |
| CO (1) | CO5070578A1 (en) |
| DZ (1) | DZ2853A1 (en) |
| GB (2) | GB9816132D0 (en) |
| JO (1) | JO2129B1 (en) |
| PE (1) | PE20001064A1 (en) |
| UY (1) | UY25622A1 (en) |
| WO (1) | WO2000004906A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU733095B3 (en) * | 1999-09-22 | 2001-05-03 | Ashmont Holdings Limited | Sheep pour on |
| AUPR602501A0 (en) * | 2001-06-29 | 2001-07-26 | Smart Drug Systems Inc | Sustained release pharmaceutical composition |
| AUPR610501A0 (en) * | 2001-07-04 | 2001-07-26 | Smart Drug Systems Inc | Treatment of parasitic disease |
| GB0316377D0 (en) * | 2003-07-12 | 2003-08-13 | Norbrook Lab Ltd | Parasiticidal composition |
| WO2022170027A1 (en) | 2021-02-04 | 2022-08-11 | Edenbridge Pharmaceuticals, LLC | Inhaled ivermectin |
| CN115399316B (en) * | 2022-09-15 | 2025-02-11 | 湖北省农业科学院植保土肥研究所 | A pesticide tank-mix adjuvant composition and its preparation method and application |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210505A (en) * | 1983-12-22 | 1988-06-30 | Merck & Co Inc | Parasiticidal compositions containing avermectin or milbemycin derivatives |
| NZ248486A (en) * | 1993-08-24 | 1996-07-26 | Ashmont Holdings Limited Subst | Stable anthelmintic formulation containing closantel and one or more avermectins or milbemycins in a glycol based solvent |
| AUPM969994A0 (en) * | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
| ZA979483B (en) * | 1996-10-25 | 1998-05-20 | Chemvet Nz Ltd | Anthelmintic formulation. |
-
1998
- 1998-07-24 GB GBGB9816132.6A patent/GB9816132D0/en not_active Ceased
-
1999
- 1999-07-03 GB GB9915531A patent/GB2339691A/en not_active Withdrawn
- 1999-07-20 JO JO19992129A patent/JO2129B1/en active
- 1999-07-21 AR ARP990103572A patent/AR020613A1/en unknown
- 1999-07-21 DZ DZ990153A patent/DZ2853A1/en active
- 1999-07-21 WO PCT/GB1999/002364 patent/WO2000004906A1/en not_active Ceased
- 1999-07-21 AU AU50540/99A patent/AU5054099A/en not_active Abandoned
- 1999-07-22 CO CO99046067A patent/CO5070578A1/en unknown
- 1999-07-22 PE PE1999000735A patent/PE20001064A1/en not_active Application Discontinuation
- 1999-07-23 UY UY25622A patent/UY25622A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| UY25622A1 (en) | 2000-02-23 |
| WO2000004906A1 (en) | 2000-02-03 |
| GB9915531D0 (en) | 1999-09-01 |
| AU5054099A (en) | 2000-02-14 |
| AR020613A1 (en) | 2002-05-22 |
| DZ2853A1 (en) | 2003-12-01 |
| CO5070578A1 (en) | 2001-08-28 |
| PE20001064A1 (en) | 2000-10-11 |
| GB9816132D0 (en) | 1998-09-23 |
| GB2339691A (en) | 2000-02-09 |
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