JO3459B1 - تركيبات صيدلانية لعلاج مرض الزهايمر - Google Patents

تركيبات صيدلانية لعلاج مرض الزهايمر

Info

Publication number
JO3459B1
JO3459B1 JOP/2013/0248A JOP20130248A JO3459B1 JO 3459 B1 JO3459 B1 JO 3459B1 JO P20130248 A JOP20130248 A JO P20130248A JO 3459 B1 JO3459 B1 JO 3459B1
Authority
JO
Jordan
Prior art keywords
alzheimer
disease
treatment
pharmaceutical formulations
span
Prior art date
Application number
JOP/2013/0248A
Other languages
Arabic (ar)
English (en)
Inventor
Schmidt Ellen
Areberg Johan
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49118521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3459(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H Lundbeck As filed Critical H Lundbeck As
Application granted granted Critical
Publication of JO3459B1 publication Critical patent/JO3459B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JOP/2013/0248A 2012-09-09 2013-08-21 تركيبات صيدلانية لعلاج مرض الزهايمر JO3459B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261698664P 2012-09-09 2012-09-09
US201361782084P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
JO3459B1 true JO3459B1 (ar) 2020-07-05

Family

ID=49118521

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2013/0248A JO3459B1 (ar) 2012-09-09 2013-08-21 تركيبات صيدلانية لعلاج مرض الزهايمر

Country Status (33)

Country Link
US (4) US9375418B2 (2)
EP (1) EP2892563B1 (2)
JP (2) JP6693744B2 (2)
KR (2) KR102342127B1 (2)
CN (1) CN104619344A (2)
AP (1) AP2015008306A0 (2)
AU (1) AU2013311573B2 (2)
BR (1) BR112015005117B1 (2)
CA (1) CA2883751C (2)
CL (1) CL2015000578A1 (2)
CY (1) CY1121062T1 (2)
DK (1) DK2892563T3 (2)
EA (1) EA030448B1 (2)
ES (1) ES2703630T3 (2)
GE (1) GEP201706776B (2)
HR (1) HRP20182069T1 (2)
IL (1) IL237369B (2)
JO (1) JO3459B1 (2)
LT (1) LT2892563T (2)
MX (1) MX368305B (2)
MY (1) MY182539A (2)
NI (1) NI201500031A (2)
NZ (1) NZ630589A (2)
PL (1) PL2892563T3 (2)
PT (1) PT2892563T (2)
RS (1) RS58104B1 (2)
RU (1) RU2675786C2 (2)
SG (1) SG11201501774QA (2)
SI (1) SI2892563T1 (2)
SM (1) SMT201800678T1 (2)
TN (1) TN2015000076A1 (2)
TW (1) TWI632909B (2)
WO (1) WO2014037532A1 (2)

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JO3459B1 (ar) 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر
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JO3509B1 (ar) 2013-03-14 2020-07-05 Janssen Pharmaceutica Nv معدلات p2x7
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JO3639B1 (ar) 2014-07-04 2020-08-27 H Lundbeck As صورة متعددة الشكل جديدة لـ n-[2-(6-فلورو-1h-إندول-3-يل)إيثيل]-3-(2،2،3،3-تترا فلورو بروبوكسي)بنزيل أمين هيدروكلوريد
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JP2018515607A (ja) * 2015-05-07 2018-06-14 アクソファント サイエンシーズ ゲーエムベーハーＡｘｏｖａｎｔ Ｓｃｉｅｎｃｅｓ Ｇｍｂｈ 神経変性疾患を処置する組成物および方法
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BR112018000728A2 (pt) 2015-07-15 2018-09-04 Axovant Sciences Gmbh resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo
US10383849B2 (en) * 2016-04-26 2019-08-20 H. Lundbeck A/S Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in Parkinson's disease patients
US10864191B2 (en) 2016-05-11 2020-12-15 H. Lundbeck A/S 5-HT6 receptor antagonists for use in the treatment of Alzheimer's disease with apathy as comorbidity
EA036347B1 (ru) 2016-05-18 2020-10-29 Сувен Лайф Сайенсиз Лимитед Комбинация чистых антагонистов 5-ht6 рецепторов с ингибиторами ацетилхолинэстеразы
CN106309436A (zh) * 2016-07-25 2017-01-11 宁波大学 可用作乙酰胆碱酯酶抑制剂的色胺衍生物及其用途
CN107118146B (zh) * 2017-04-13 2019-09-03 宁波大学 一种6-溴色胺衍生物及其制备方法和用途
BR112019001145A2 (pt) * 2017-05-24 2019-04-30 H. Lundbeck A/S combinação de um antagonista do receptor 5-ht6 e de um inibidor de acetilcolinesterase para uso no tratamento da doença de alzheimer em uma subpopulação de pacientes portadores de alelos de apoe4
MY205440A (en) 2018-09-28 2024-10-21 Janssen Pharmaceutica Nv Monoacylglycerol lipase modulators
KR20210069079A (ko) 2018-09-28 2021-06-10 얀센 파마슈티카 엔.브이. 모노아실글리세롤 리파아제 조절제
JP7697934B2 (ja) 2019-09-30 2025-06-24 ヤンセン ファーマシューティカ エヌ．ベー． 放射線標識されたｍｇｌ ｐｅｔリガンド
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BR112022019077A2 (pt) 2020-03-26 2022-12-27 Janssen Pharmaceutica Nv Moduladores da monoacilglicerol lipase
EP3960174B1 (en) 2020-08-28 2024-10-30 Westfälische Wilhelms-Universität Münster Parasympathetic active phenyl-glycosid-substituted hydroxy-methyl-piperidine and -pyrrolidine alkaloids for medicinal use
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Also Published As

Publication number Publication date
BR112015005117A2 (pt) 2017-07-04
IL237369B (en) 2018-11-29
SG11201501774QA (en) 2015-05-28
MX2015002879A (es) 2015-07-06
CA2883751A1 (en) 2014-03-13
US20160256437A1 (en) 2016-09-08
AU2013311573B2 (en) 2017-10-12
BR112015005117B1 (pt) 2022-06-21
WO2014037532A1 (en) 2014-03-13
AU2013311573A1 (en) 2015-03-12
RU2675786C2 (ru) 2018-12-25
TW201414474A (zh) 2014-04-16
US10660878B2 (en) 2020-05-26
CY1121062T1 (el) 2019-12-11
TN2015000076A1 (en) 2016-06-29
KR20150065680A (ko) 2015-06-15
US20180071254A1 (en) 2018-03-15
DK2892563T3 (en) 2019-01-21
RS58104B1 (sr) 2019-02-28
SI2892563T1 (sl) 2019-02-28
NI201500031A (es) 2016-02-15
JP2019059760A (ja) 2019-04-18
CA2883751C (en) 2020-11-24
US9687473B2 (en) 2017-06-27
JP6693744B2 (ja) 2020-05-13
AU2013311573A8 (en) 2015-03-19
HK1212217A1 (en) 2016-06-10
AP2015008306A0 (en) 2015-03-31
LT2892563T (lt) 2019-01-10
EP2892563B1 (en) 2018-11-14
MY182539A (en) 2021-01-25
CL2015000578A1 (es) 2015-05-15
US20160354343A1 (en) 2016-12-08
KR102342127B1 (ko) 2021-12-21
NZ630589A (en) 2015-12-24
KR20200137028A (ko) 2020-12-08
US9375418B2 (en) 2016-06-28
IL237369A0 (en) 2015-04-30
EA201590353A1 (ru) 2016-03-31
EA030448B1 (ru) 2018-08-31
US9789085B2 (en) 2017-10-17
RU2015107877A (ru) 2016-10-27
MX368305B (es) 2019-09-27
GEP201706776B (en) 2017-11-27
HRP20182069T1 (hr) 2019-02-08
CN104619344A (zh) 2015-05-13
PL2892563T3 (pl) 2019-04-30
PT2892563T (pt) 2019-01-10
SMT201800678T1 (it) 2019-02-28
TWI632909B (zh) 2018-08-21
EP2892563A1 (en) 2015-07-15
US20140073681A1 (en) 2014-03-13
JP2015528471A (ja) 2015-09-28
ES2703630T3 (es) 2019-03-11

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