JOP20170197B1 - الصيغة الجديدة التي تشتمل على مشتق بنزيميدازول - Google Patents

الصيغة الجديدة التي تشتمل على مشتق بنزيميدازول

Info

Publication number
JOP20170197B1
JOP20170197B1 JOJO/P/2017/0197A JOP20170197A JOP20170197B1 JO P20170197 B1 JOP20170197 B1 JO P20170197B1 JO P20170197 A JOP20170197 A JO P20170197A JO P20170197 B1 JOP20170197 B1 JO P20170197B1
Authority
JO
Jordan
Prior art keywords
formulation
benzimidazole derivative
new formulation
oral administration
present
Prior art date
Application number
JOJO/P/2017/0197A
Other languages
English (en)
Original Assignee
Lim Hyungsuk
Lyu Chun Seon
Park Sun Young
Shin Kyungmin
Oh Da Won
Hk Inno N Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62710016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JOP20170197(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lim Hyungsuk, Lyu Chun Seon, Park Sun Young, Shin Kyungmin, Oh Da Won, Hk Inno N Corp filed Critical Lim Hyungsuk
Publication of JOP20170197A1 publication Critical patent/JOP20170197A1/ar
Application granted granted Critical
Publication of JOP20170197B1 publication Critical patent/JOP20170197B1/ar

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

يتعلق الاختراع الحالي بتركيبة جديدة تشتمل على مشتق بينزيميدازول. حيث تُظهر التركيبة للإعطاء عن طريق الفم- التي تشتمل على مركب بالصيغة 1 وفقا للاختراع الحالي أو ملح مقبول صيدلانيا منه؛ ومفتت واحد على الأقل تم اختياره من المجموعة التي تتكون من كروس كارميلوز الصوديوم، جليكولات الصوديوم النشوية وهيدروكسي بروبيل سيلولوز منخفض الاستبدال- استقرار ممتاز للتخزين ولها تأثير على منع ظاهرة انخفاض معدل الذوبان، وبالتالي يتم استخدامها على نحو مفيد كتركيبة للإعطاء عن طريق الفم.
JOJO/P/2017/0197A 2016-12-26 2017-12-26 الصيغة الجديدة التي تشتمل على مشتق بنزيميدازول JOP20170197B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020160179334A KR101960357B1 (ko) 2016-12-26 2016-12-26 벤즈이미다졸 유도체를 포함하는 신규한 제제

Publications (2)

Publication Number Publication Date
JOP20170197A1 JOP20170197A1 (ar) 2019-01-30
JOP20170197B1 true JOP20170197B1 (ar) 2022-03-15

Family

ID=62710016

Family Applications (1)

Application Number Title Priority Date Filing Date
JOJO/P/2017/0197A JOP20170197B1 (ar) 2016-12-26 2017-12-26 الصيغة الجديدة التي تشتمل على مشتق بنزيميدازول

Country Status (14)

Country Link
US (2) US11576898B2 (ar)
EP (1) EP3560482B9 (ar)
JP (1) JP6814886B2 (ar)
KR (1) KR101960357B1 (ar)
CN (2) CN116869915A (ar)
AR (1) AR110453A1 (ar)
ES (1) ES2887020T3 (ar)
JO (1) JOP20170197B1 (ar)
MX (1) MX390201B (ar)
MY (1) MY191261A (ar)
PH (1) PH12019501288A1 (ar)
TW (1) TWI658841B (ar)
UY (1) UY37550A (ar)
WO (1) WO2018124700A1 (ar)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3927340T3 (pl) * 2019-02-18 2026-03-09 Hk Inno.N Corporation Kompozycja farmaceutyczna zawierająca tegoprazan do zapobiegania nawrotowi choroby refluksowej przełyku
WO2021209892A1 (en) * 2020-04-13 2021-10-21 Hk Inno.N Corporation Pharmaceutical composition comprising benzimidazole derivative compound
WO2022086238A1 (en) * 2020-10-23 2022-04-28 Hk Inno.N Corporation Orally disintegrating tablet comprising benzimidazole derivative compound and preparation method thereof
WO2024228133A1 (en) * 2023-05-02 2024-11-07 Metrochem Api Pvt Ltd Novel salts of tegoprazan and its polymorphs
KR20250178892A (ko) * 2024-06-20 2025-12-29 화일약품주식회사 테고프라잔의 신규 염 및 이의 제조방법
DE102024002434A1 (de) 2024-07-25 2026-01-29 Mercedes-Benz Group AG Modulare Einheit zur Anordnung in einer Nabe eines Fahrzeugrades mit beweglichen Aeroelementen und Rad für ein Kraftfahrzeug

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101088247B1 (ko) 2005-12-19 2011-11-30 라퀄리아 파마 인코포레이티드 크로메인 치환된 벤즈이미다졸 및 이들의 산 펌프억제제로서의 용도
CA2654402A1 (en) * 2006-06-01 2007-12-06 Adel Penhasi Multiple unit pharmaceutical formulation
US9034860B2 (en) 2006-12-07 2015-05-19 Daiichi Sankyo Company, Limited Pharmaceutical composition containing low-substituted hydroxypropyl cellulose
HUE056322T2 (hu) 2015-06-08 2022-02-28 Hk Inno N Corp Benzimidazol-származék alkalmazásai éjszakai savvisszaáramláshoz

Also Published As

Publication number Publication date
CN116869915A (zh) 2023-10-13
MX390201B (es) 2025-03-20
ES2887020T3 (es) 2021-12-21
MY191261A (en) 2022-06-12
JOP20170197A1 (ar) 2019-01-30
KR101960357B1 (ko) 2019-03-20
CN110121333A (zh) 2019-08-13
US11576898B2 (en) 2023-02-14
UY37550A (es) 2018-07-31
CN110121333B (zh) 2023-07-04
AR110453A1 (es) 2019-03-27
MX2019007239A (es) 2019-08-16
JP6814886B2 (ja) 2021-01-20
TW201828928A (zh) 2018-08-16
JP2020502208A (ja) 2020-01-23
EP3560482B1 (en) 2021-08-18
EP3560482A1 (en) 2019-10-30
TWI658841B (zh) 2019-05-11
KR20180075235A (ko) 2018-07-04
PH12019501288A1 (en) 2019-12-02
EP3560482A4 (en) 2020-08-19
US20230277506A1 (en) 2023-09-07
US20200392120A1 (en) 2020-12-17
WO2018124700A1 (ko) 2018-07-05
EP3560482B9 (en) 2022-04-20
BR112019013098A2 (pt) 2019-12-17

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