JOP20200005B1 - تركيبات صيدلية - Google Patents

تركيبات صيدلية

Info

Publication number
JOP20200005B1
JOP20200005B1 JOJO/P/2020/0005A JOP20200005A JOP20200005B1 JO P20200005 B1 JOP20200005 B1 JO P20200005B1 JO P20200005 A JOP20200005 A JO P20200005A JO P20200005 B1 JOP20200005 B1 JO P20200005B1
Authority
JO
Jordan
Prior art keywords
pharmaceutical formulations
valsartan
atorvastatin
metformin
formulation
Prior art date
Application number
JOJO/P/2020/0005A
Other languages
English (en)
Inventor
Matthew Carl Allgeier
Tony Yantao Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of JOP20200005A1 publication Critical patent/JOP20200005A1/ar
Application granted granted Critical
Publication of JOP20200005B1 publication Critical patent/JOP20200005B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

يتعلق الاختراع الحالي بتركيبات ذات جرعة ثابتة فموية صلبة من ميتفورمين، وأتور?استاتين، و?السارتان، أو أملاح مقبولة صيدليًا منها، وعمليات لتحضيرها، واستخدام التركيبة لعلاج أمراض محددة.
JOJO/P/2020/0005A 2017-07-17 2020-01-14 تركيبات صيدلية JOP20200005B1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762533332P 2017-07-17 2017-07-17
US201762538936P 2017-07-31 2017-07-31
PCT/US2018/041378 WO2019018155A1 (en) 2017-07-17 2018-07-10 PHARMACEUTICAL COMPOSITIONS

Publications (2)

Publication Number Publication Date
JOP20200005A1 JOP20200005A1 (ar) 2020-01-14
JOP20200005B1 true JOP20200005B1 (ar) 2024-04-18

Family

ID=63036446

Family Applications (2)

Application Number Title Priority Date Filing Date
JOJO/P/2020/0005A JOP20200005B1 (ar) 2017-07-17 2020-01-14 تركيبات صيدلية
JOJO/P/2023/0099A JOP20230099A1 (ar) 2017-07-17 2023-05-04 تركيبات صيدلية

Family Applications After (1)

Application Number Title Priority Date Filing Date
JOJO/P/2023/0099A JOP20230099A1 (ar) 2017-07-17 2023-05-04 تركيبات صيدلية

Country Status (25)

Country Link
US (2) US11376223B2 (ar)
EP (1) EP3654955B1 (ar)
JP (1) JP6854384B2 (ar)
KR (1) KR102409102B1 (ar)
CN (1) CN110913843B (ar)
AU (1) AU2018301924B2 (ar)
BR (1) BR112019028278A2 (ar)
CA (1) CA3069948C (ar)
CL (1) CL2020000120A1 (ar)
CO (1) CO2019015099A2 (ar)
CR (1) CR20190577A (ar)
DO (1) DOP2020000010A (ar)
EC (1) ECSP20003493A (ar)
ES (1) ES3032318T3 (ar)
IL (1) IL272044A (ar)
JO (2) JOP20200005B1 (ar)
MA (1) MA49625A (ar)
MY (1) MY198062A (ar)
PE (1) PE20200174A1 (ar)
PH (1) PH12020500120A1 (ar)
SA (1) SA520410976B1 (ar)
SG (1) SG11201912482WA (ar)
UA (1) UA125535C2 (ar)
WO (1) WO2019018155A1 (ar)
ZA (1) ZA201908550B (ar)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102409102B1 (ko) * 2017-07-17 2022-06-16 일라이 릴리 앤드 캄파니 제약 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2248908T7 (es) 1997-06-06 2014-11-24 Depomed, Inc. Formas de dosificación de fármacos por vía oral y retención gástrica para liberación continuada de fármacos altamente solubles
EP1063973B1 (en) 1998-03-19 2016-11-16 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
PE20020617A1 (es) * 2000-08-22 2002-08-05 Novartis Ag Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
US8329217B2 (en) * 2001-11-06 2012-12-11 Osmotica Kereskedelmi Es Szolgaltato Kft Dual controlled release dosage form
CA2494916A1 (en) * 2002-08-08 2004-02-19 Sankyo Company Limited Medicinal composition for lowering blood lipid level
US20050013863A1 (en) * 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
JP5467870B2 (ja) 2007-02-09 2014-04-09 アルファファーム ピーティーワイ リミテッド 異なる物理的形態の２種以上の有効医薬成分を含有する投薬形態
US8574625B2 (en) * 2007-05-30 2013-11-05 Wockhardt Ltd. Tablet dosage form
WO2012010977A2 (en) 2010-07-21 2012-01-26 Nucitec S.A. De C.V. Single daily dosage form for prevention and treatment of metabolic syndrome
US9572784B2 (en) * 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
CA2866377C (en) * 2012-03-30 2020-02-11 Daewoong Pharmaceutical Co., Ltd. Pharmaceutical composition comprising olmesartan medoxomil and rosuvastatin or its salt
KR20140028971A (ko) * 2012-08-31 2014-03-10 한미약품 주식회사 아토바스타틴, 이르베살탄 및 탄산마그네슘을 포함하는 이층정 복합제제
CN103054856A (zh) * 2012-12-30 2013-04-24 成都恒瑞制药有限公司 含有盐酸二甲双胍和阿托伐他汀钙的固体口服制剂
KR101597004B1 (ko) * 2013-07-25 2016-02-23 씨제이헬스케어 주식회사 서방형 메트포르민과 속방형 HMG-CoA 환원효소 억제제를 포함하는 복합제제
BR102013028883A2 (pt) 2013-11-08 2015-10-06 Hypermarcas S A forma farmacêutica oral para a prevenção de doenças vasculares, comprimido como forma farmacêutica e cápsula gelatinosa como forma farmacêutica
WO2016040462A2 (en) * 2014-09-09 2016-03-17 ARKAY Therapeutics, LLC Formulations and methods for treatment of metabolic syndrome
KR102409102B1 (ko) * 2017-07-17 2022-06-16 일라이 릴리 앤드 캄파니 제약 조성물

Also Published As

Publication number Publication date
MY198062A (en) 2023-07-31
US11918692B2 (en) 2024-03-05
BR112019028278A2 (pt) 2020-07-14
DOP2020000010A (es) 2020-02-28
PE20200174A1 (es) 2020-01-24
SA520410976B1 (ar) 2023-03-23
ZA201908550B (en) 2024-06-26
EP3654955A1 (en) 2020-05-27
CA3069948A1 (en) 2019-01-24
US20210137842A1 (en) 2021-05-13
CN110913843B (zh) 2022-09-13
EP3654955C0 (en) 2025-05-07
CO2019015099A2 (es) 2020-01-17
KR20200015758A (ko) 2020-02-12
KR102409102B1 (ko) 2022-06-16
SG11201912482WA (en) 2020-02-27
ES3032318T3 (en) 2025-07-17
CN110913843A (zh) 2020-03-24
US20220287978A1 (en) 2022-09-15
PH12020500120A1 (en) 2020-09-28
CA3069948C (en) 2022-05-17
IL272044A (en) 2020-03-31
US11376223B2 (en) 2022-07-05
NZ760868A (en) 2023-09-29
CL2020000120A1 (es) 2020-07-17
CR20190577A (es) 2020-01-29
MA49625A (fr) 2020-05-27
ECSP20003493A (es) 2020-08-31
UA125535C2 (uk) 2022-04-13
JP2020527147A (ja) 2020-09-03
WO2019018155A1 (en) 2019-01-24
JP6854384B2 (ja) 2021-04-07
JOP20200005A1 (ar) 2020-01-14
AU2018301924B2 (en) 2021-07-29
JOP20230099A1 (ar) 2023-05-04
EP3654955B1 (en) 2025-05-07
AU2018301924A1 (en) 2019-12-19

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