JOP20200069A1 - أجسام مضادة لـ pacap - Google Patents
أجسام مضادة لـ pacapInfo
- Publication number
- JOP20200069A1 JOP20200069A1 JOP/2020/0069A JOP20200069A JOP20200069A1 JO P20200069 A1 JOP20200069 A1 JO P20200069A1 JO P20200069 A JOP20200069 A JO P20200069A JO P20200069 A1 JOP20200069 A1 JO P20200069A1
- Authority
- JO
- Jordan
- Prior art keywords
- antibodies
- pacap antibody
- migraine
- compositions
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
يتعلق الاختراع الحالي بأجسام مضادة لببتيد منشط سيكلاز الأدينيلات النخامية، وتركيبات تشتمل على تلك الأجسام المضادة، وطرق استخدام هذه الأجسام المضادة لعلاج الألم الذي يتضمن الصداع و/أو الصداع النصفي.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762565278P | 2017-09-29 | 2017-09-29 | |
| PCT/US2018/051898 WO2019067293A1 (en) | 2017-09-29 | 2018-09-20 | ANTI-PACAP ANTIBODIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JOP20200069A1 true JOP20200069A1 (ar) | 2020-04-28 |
Family
ID=63794713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2020/0069A JOP20200069A1 (ar) | 2017-09-29 | 2018-09-20 | أجسام مضادة لـ pacap |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10519225B2 (ar) |
| EP (1) | EP3688035A1 (ar) |
| JP (2) | JP6952888B2 (ar) |
| KR (1) | KR102453573B1 (ar) |
| CN (1) | CN111164105B (ar) |
| AR (1) | AR113022A1 (ar) |
| AU (1) | AU2018341959B2 (ar) |
| BR (1) | BR112020003628A2 (ar) |
| CA (1) | CA3077304C (ar) |
| CL (1) | CL2020000705A1 (ar) |
| CO (1) | CO2020002170A2 (ar) |
| CR (1) | CR20200127A (ar) |
| DO (1) | DOP2020000060A (ar) |
| EA (1) | EA202090563A1 (ar) |
| EC (1) | ECSP20020293A (ar) |
| IL (1) | IL273529A (ar) |
| JO (1) | JOP20200069A1 (ar) |
| MA (1) | MA50654A (ar) |
| MX (1) | MX2020003563A (ar) |
| MY (1) | MY199876A (ar) |
| NZ (1) | NZ762312A (ar) |
| PE (1) | PE20201494A1 (ar) |
| PH (1) | PH12020550340A1 (ar) |
| SG (1) | SG11202002572YA (ar) |
| TW (1) | TWI701260B (ar) |
| WO (1) | WO2019067293A1 (ar) |
| ZA (1) | ZA202001058B (ar) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2982861A1 (en) | 2015-04-16 | 2016-10-20 | Alder Biopharmaceuticals, Inc. | Anti-pacap antibodies and uses thereof |
| EP3426288A4 (en) | 2016-04-15 | 2019-10-30 | Alder Biopharmaceuticals, Inc. | ANTI-PACAP ANTIBODIES AND USES THEREOF |
| EP4045641A1 (en) | 2019-10-15 | 2022-08-24 | Eli Lilly and Company | Recombinantly engineered, lipase/esterase-deficient mammalian cell lines |
| WO2023010065A2 (en) * | 2021-07-29 | 2023-02-02 | Cephalon Llc | Compositions and methods for anti-pacap antibodies |
| CN117916259A (zh) * | 2021-09-30 | 2024-04-19 | 江苏恒瑞医药股份有限公司 | 特异性结合cgrp和pacap的抗原结合分子及其医药用途 |
| KR102839881B1 (ko) * | 2021-11-19 | 2025-07-31 | 대한민국 | 방송통신기자재 성능 측정 시스템 및 그 방법 |
| WO2024218541A1 (en) * | 2023-04-20 | 2024-10-24 | Mark Hasleton | Treatment of migraine |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5486472A (en) | 1990-03-17 | 1996-01-23 | Takeda Chemical Industries, Ltd. | Monoclonal antibodies to PACAP |
| US6037321A (en) | 1995-05-03 | 2000-03-14 | Biostar Inc. | Fusion proteins comprising vasoactive intestinal peptide or PACAP |
| FR2826747B1 (fr) | 2001-07-02 | 2005-02-25 | Gemplus Card Int | Procede et dispositif de traitement de donnees pour la personnalisation d'une application sur un dispositif communicant portatif, par exemple une carte a puce |
| US7615219B2 (en) | 2003-01-16 | 2009-11-10 | Life Sciences Research Partners Vzw | Inhibition of PACAP signalling for the prevention and treatment of thrombocytopenia |
| WO2012106407A2 (en) | 2011-02-01 | 2012-08-09 | The University Of Vermont And State Agricultural College | Diagnostic and therapeutic methods and products related to anxiety disorders |
| JP6064861B2 (ja) | 2013-03-05 | 2017-01-25 | 株式会社デンソー | 熱電変換装置の製造方法 |
| CA2906737C (en) * | 2013-03-15 | 2023-08-15 | Amgen Inc. | Human pac1 antibodies |
| EP3035950A4 (en) | 2013-08-14 | 2017-05-03 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Glycosylated pacap/vip analogues with enhanced cns penetration for treatment of neurodegenerative diseases |
| CA2982861A1 (en) | 2015-04-16 | 2016-10-20 | Alder Biopharmaceuticals, Inc. | Anti-pacap antibodies and uses thereof |
| US10822408B2 (en) * | 2015-12-15 | 2020-11-03 | Amgen Inc. | PACAP antibodies and uses thereof |
| WO2017142961A1 (en) | 2016-02-16 | 2017-08-24 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Treatment of traumatic brain injury or stroke |
-
2018
- 2018-09-13 AR ARP180102618A patent/AR113022A1/es not_active Application Discontinuation
- 2018-09-14 TW TW107132467A patent/TWI701260B/zh active
- 2018-09-20 MA MA050654A patent/MA50654A/fr unknown
- 2018-09-20 KR KR1020207008789A patent/KR102453573B1/ko active Active
- 2018-09-20 CA CA3077304A patent/CA3077304C/en active Active
- 2018-09-20 CN CN201880063106.2A patent/CN111164105B/zh active Active
- 2018-09-20 SG SG11202002572YA patent/SG11202002572YA/en unknown
- 2018-09-20 WO PCT/US2018/051898 patent/WO2019067293A1/en not_active Ceased
- 2018-09-20 EA EA202090563A patent/EA202090563A1/ru unknown
- 2018-09-20 BR BR112020003628-5A patent/BR112020003628A2/pt not_active Application Discontinuation
- 2018-09-20 NZ NZ762312A patent/NZ762312A/en not_active IP Right Cessation
- 2018-09-20 MY MYPI2020001596A patent/MY199876A/en unknown
- 2018-09-20 JO JOP/2020/0069A patent/JOP20200069A1/ar unknown
- 2018-09-20 CR CR20200127A patent/CR20200127A/es unknown
- 2018-09-20 US US16/136,490 patent/US10519225B2/en active Active
- 2018-09-20 EP EP18783282.9A patent/EP3688035A1/en active Pending
- 2018-09-20 JP JP2020517489A patent/JP6952888B2/ja active Active
- 2018-09-20 PE PE2020000375A patent/PE20201494A1/es unknown
- 2018-09-20 AU AU2018341959A patent/AU2018341959B2/en not_active Ceased
- 2018-09-20 PH PH1/2020/550340A patent/PH12020550340A1/en unknown
- 2018-09-20 MX MX2020003563A patent/MX2020003563A/es unknown
-
2019
- 2019-11-22 US US16/692,236 patent/US10954292B2/en active Active
-
2020
- 2020-02-19 ZA ZA2020/01058A patent/ZA202001058B/en unknown
- 2020-02-27 CO CONC2020/0002170A patent/CO2020002170A2/es unknown
- 2020-03-16 DO DO2020000060A patent/DOP2020000060A/es unknown
- 2020-03-18 CL CL2020000705A patent/CL2020000705A1/es unknown
- 2020-03-23 IL IL273529A patent/IL273529A/en unknown
- 2020-03-26 EC ECSENADI202020293A patent/ECSP20020293A/es unknown
-
2021
- 2021-02-15 US US17/175,870 patent/US20210171616A1/en not_active Abandoned
- 2021-09-28 JP JP2021157701A patent/JP7221352B2/ja active Active
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