JOP20200069A1 - أجسام مضادة لـ pacap - Google Patents
أجسام مضادة لـ pacapInfo
- Publication number
- JOP20200069A1 JOP20200069A1 JOP/2020/0069A JOP20200069A JOP20200069A1 JO P20200069 A1 JOP20200069 A1 JO P20200069A1 JO P20200069 A JOP20200069 A JO P20200069A JO P20200069 A1 JOP20200069 A1 JO P20200069A1
- Authority
- JO
- Jordan
- Prior art keywords
- antibodies
- pacap antibody
- migraine
- compositions
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
يتعلق الاختراع الحالي بأجسام مضادة لببتيد منشط سيكلاز الأدينيلات النخامية، وتركيبات تشتمل على تلك الأجسام المضادة، وطرق استخدام هذه الأجسام المضادة لعلاج الألم الذي يتضمن الصداع و/أو الصداع النصفي.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762565278P | 2017-09-29 | 2017-09-29 | |
| PCT/US2018/051898 WO2019067293A1 (en) | 2017-09-29 | 2018-09-20 | ANTI-PACAP ANTIBODIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JOP20200069A1 true JOP20200069A1 (ar) | 2020-04-28 |
Family
ID=63794713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2020/0069A JOP20200069A1 (ar) | 2017-09-29 | 2018-09-20 | أجسام مضادة لـ pacap |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10519225B2 (ar) |
| EP (1) | EP3688035A1 (ar) |
| JP (2) | JP6952888B2 (ar) |
| KR (1) | KR102453573B1 (ar) |
| CN (1) | CN111164105B (ar) |
| AR (1) | AR113022A1 (ar) |
| AU (1) | AU2018341959B2 (ar) |
| BR (1) | BR112020003628A2 (ar) |
| CA (1) | CA3077304C (ar) |
| CL (1) | CL2020000705A1 (ar) |
| CO (1) | CO2020002170A2 (ar) |
| CR (1) | CR20200127A (ar) |
| DO (1) | DOP2020000060A (ar) |
| EA (1) | EA202090563A1 (ar) |
| EC (1) | ECSP20020293A (ar) |
| IL (1) | IL273529A (ar) |
| JO (1) | JOP20200069A1 (ar) |
| MA (1) | MA50654A (ar) |
| MX (1) | MX2020003563A (ar) |
| MY (1) | MY199876A (ar) |
| NZ (1) | NZ762312A (ar) |
| PE (1) | PE20201494A1 (ar) |
| PH (1) | PH12020550340A1 (ar) |
| SG (1) | SG11202002572YA (ar) |
| TW (1) | TWI701260B (ar) |
| WO (1) | WO2019067293A1 (ar) |
| ZA (1) | ZA202001058B (ar) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10899834B2 (en) | 2015-04-16 | 2021-01-26 | H. Lundbeck A/S | Anti-PACAP antibodies |
| KR102444717B1 (ko) | 2016-04-15 | 2022-09-16 | 하. 룬드벡 아크티에셀스카브 | 인간화 항-pacap 항체 및 그의 용도 |
| CN114555792A (zh) | 2019-10-15 | 2022-05-27 | 伊莱利利公司 | 重组改造的、脂肪酶/酯酶缺陷型哺乳动物细胞系 |
| PE20240809A1 (es) * | 2021-07-29 | 2024-04-18 | Cephalon Llc | Composiciones y metodos de los anticuerpos anti-pacap |
| WO2023051786A1 (zh) * | 2021-09-30 | 2023-04-06 | 江苏恒瑞医药股份有限公司 | 特异性结合cgrp和pacap的抗原结合分子及其医药用途 |
| KR102839881B1 (ko) * | 2021-11-19 | 2025-07-31 | 대한민국 | 방송통신기자재 성능 측정 시스템 및 그 방법 |
| WO2024218541A1 (en) * | 2023-04-20 | 2024-10-24 | Mark Hasleton | Treatment of migraine |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2077764C (en) * | 1990-03-17 | 2002-12-10 | Nobuhiro Suzuki | Antibody to pacap and use thereof |
| US6037321A (en) | 1995-05-03 | 2000-03-14 | Biostar Inc. | Fusion proteins comprising vasoactive intestinal peptide or PACAP |
| FR2826747B1 (fr) | 2001-07-02 | 2005-02-25 | Gemplus Card Int | Procede et dispositif de traitement de donnees pour la personnalisation d'une application sur un dispositif communicant portatif, par exemple une carte a puce |
| WO2004062684A2 (en) | 2003-01-16 | 2004-07-29 | D. Collen Research Foundation Vzw Onderwijs En Navorsing Campus Gasthuisberg K.U. Leuven | Treatment of thrombocytopenia with inhibitors of pacap |
| US9939449B2 (en) | 2011-02-01 | 2018-04-10 | The University Of Vermont And State Agricultural College | Diagnostic and therapeutic methods and products related to anxiety disorders |
| JP6064861B2 (ja) | 2013-03-05 | 2017-01-25 | 株式会社デンソー | 熱電変換装置の製造方法 |
| CA2906737C (en) * | 2013-03-15 | 2023-08-15 | Amgen Inc. | Human pac1 antibodies |
| WO2015023890A1 (en) | 2013-08-14 | 2015-02-19 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Glycosylated pacap/vip analogues with enhanced cns penetration for treatment of neurodegenerative diseases |
| US10899834B2 (en) | 2015-04-16 | 2021-01-26 | H. Lundbeck A/S | Anti-PACAP antibodies |
| US10822408B2 (en) * | 2015-12-15 | 2020-11-03 | Amgen Inc. | PACAP antibodies and uses thereof |
| EP3416977A4 (en) | 2016-02-16 | 2019-07-17 | The Arizona Board of Regents On Behalf of the University of Arizona | TREATMENT OF TRAUMATIC BRAIN INJURY OR IMPACT |
-
2018
- 2018-09-13 AR ARP180102618A patent/AR113022A1/es not_active Application Discontinuation
- 2018-09-14 TW TW107132467A patent/TWI701260B/zh active
- 2018-09-20 US US16/136,490 patent/US10519225B2/en active Active
- 2018-09-20 BR BR112020003628-5A patent/BR112020003628A2/pt not_active Application Discontinuation
- 2018-09-20 MX MX2020003563A patent/MX2020003563A/es unknown
- 2018-09-20 JP JP2020517489A patent/JP6952888B2/ja active Active
- 2018-09-20 CR CR20200127A patent/CR20200127A/es unknown
- 2018-09-20 KR KR1020207008789A patent/KR102453573B1/ko active Active
- 2018-09-20 CN CN201880063106.2A patent/CN111164105B/zh active Active
- 2018-09-20 EA EA202090563A patent/EA202090563A1/ru unknown
- 2018-09-20 SG SG11202002572YA patent/SG11202002572YA/en unknown
- 2018-09-20 EP EP18783282.9A patent/EP3688035A1/en active Pending
- 2018-09-20 NZ NZ762312A patent/NZ762312A/en not_active IP Right Cessation
- 2018-09-20 PE PE2020000375A patent/PE20201494A1/es unknown
- 2018-09-20 CA CA3077304A patent/CA3077304C/en active Active
- 2018-09-20 MA MA050654A patent/MA50654A/fr unknown
- 2018-09-20 WO PCT/US2018/051898 patent/WO2019067293A1/en not_active Ceased
- 2018-09-20 MY MYPI2020001596A patent/MY199876A/en unknown
- 2018-09-20 PH PH1/2020/550340A patent/PH12020550340A1/en unknown
- 2018-09-20 JO JOP/2020/0069A patent/JOP20200069A1/ar unknown
- 2018-09-20 AU AU2018341959A patent/AU2018341959B2/en not_active Ceased
-
2019
- 2019-11-22 US US16/692,236 patent/US10954292B2/en active Active
-
2020
- 2020-02-19 ZA ZA2020/01058A patent/ZA202001058B/en unknown
- 2020-02-27 CO CONC2020/0002170A patent/CO2020002170A2/es unknown
- 2020-03-16 DO DO2020000060A patent/DOP2020000060A/es unknown
- 2020-03-18 CL CL2020000705A patent/CL2020000705A1/es unknown
- 2020-03-23 IL IL273529A patent/IL273529A/en unknown
- 2020-03-26 EC ECSENADI202020293A patent/ECSP20020293A/es unknown
-
2021
- 2021-02-15 US US17/175,870 patent/US20210171616A1/en not_active Abandoned
- 2021-09-28 JP JP2021157701A patent/JP7221352B2/ja active Active
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