JOP20200318A1 - عوامل تثبيط ask1 - Google Patents
عوامل تثبيط ask1Info
- Publication number
- JOP20200318A1 JOP20200318A1 JOP/2020/0318A JOP20200318A JOP20200318A1 JO P20200318 A1 JOP20200318 A1 JO P20200318A1 JO P20200318 A JOP20200318 A JO P20200318A JO P20200318 A1 JOP20200318 A1 JO P20200318A1
- Authority
- JO
- Jordan
- Prior art keywords
- inhibiting agents
- ask1
- ask1 inhibiting
- agents
- available
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
غير متوفر
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862690674P | 2018-06-27 | 2018-06-27 | |
| PCT/US2019/039156 WO2020006031A1 (en) | 2018-06-27 | 2019-06-26 | Ask1 inhibiting agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JOP20200318A1 true JOP20200318A1 (ar) | 2020-12-10 |
Family
ID=67254023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2020/0318A JOP20200318A1 (ar) | 2018-06-27 | 2019-06-26 | عوامل تثبيط ask1 |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US11814362B2 (ar) |
| EP (1) | EP3814333B1 (ar) |
| JP (1) | JP2021528456A (ar) |
| KR (1) | KR20210024532A (ar) |
| CN (1) | CN112638896A (ar) |
| AR (1) | AR115636A1 (ar) |
| AU (1) | AU2019291806A1 (ar) |
| BR (1) | BR112020026423A2 (ar) |
| CA (1) | CA3104662A1 (ar) |
| CL (1) | CL2020003375A1 (ar) |
| CO (1) | CO2021000782A2 (ar) |
| CR (1) | CR20210049A (ar) |
| EA (1) | EA202190034A1 (ar) |
| ES (1) | ES3032286T3 (ar) |
| IL (1) | IL279709A (ar) |
| JO (1) | JOP20200318A1 (ar) |
| MA (1) | MA53009A (ar) |
| MX (1) | MX2020013895A (ar) |
| PE (1) | PE20211379A1 (ar) |
| SG (1) | SG11202012784SA (ar) |
| TW (1) | TW202035389A (ar) |
| UY (1) | UY38278A (ar) |
| WO (1) | WO2020006031A1 (ar) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112654621B (zh) | 2018-06-27 | 2024-05-14 | 百时美施贵宝公司 | 可作为t细胞活化剂的经取代萘啶酮化合物 |
| MX2020013895A (es) | 2018-06-27 | 2021-07-21 | Biogen Ma Inc | Agentes inhibidores de ask1. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| TWI491606B (zh) * | 2009-07-13 | 2015-07-11 | Gilead Sciences Inc | 調節細胞凋亡信號之激酶的抑制劑 |
| UY35212A (es) * | 2012-12-21 | 2014-06-30 | Gilead Sciences Inc | Inhibidores de la quinasa que regula la señal de la apoptosis |
| PE20160859A1 (es) * | 2013-12-20 | 2016-09-18 | Gilead Sciences Inc | Inhibidores de la quinasa reguladora de la senal de apoptosis |
| WO2018151830A1 (en) | 2017-02-17 | 2018-08-23 | Fronthera U.S. Pharmaceuticals Llc | Pyridinyl based apoptosis signal-regulation kinase inhibitors |
| MX2020013895A (es) | 2018-06-27 | 2021-07-21 | Biogen Ma Inc | Agentes inhibidores de ask1. |
-
2019
- 2019-06-26 MX MX2020013895A patent/MX2020013895A/es unknown
- 2019-06-26 US US17/253,269 patent/US11814362B2/en active Active
- 2019-06-26 JO JOP/2020/0318A patent/JOP20200318A1/ar unknown
- 2019-06-26 AR ARP190101780A patent/AR115636A1/es not_active Application Discontinuation
- 2019-06-26 MA MA053009A patent/MA53009A/fr unknown
- 2019-06-26 AU AU2019291806A patent/AU2019291806A1/en not_active Abandoned
- 2019-06-26 PE PE2020002138A patent/PE20211379A1/es unknown
- 2019-06-26 CN CN201980042586.9A patent/CN112638896A/zh active Pending
- 2019-06-26 EP EP19739494.3A patent/EP3814333B1/en active Active
- 2019-06-26 BR BR112020026423-7A patent/BR112020026423A2/pt not_active Application Discontinuation
- 2019-06-26 KR KR1020217000614A patent/KR20210024532A/ko not_active Withdrawn
- 2019-06-26 TW TW108122356A patent/TW202035389A/zh unknown
- 2019-06-26 UY UY0001038278A patent/UY38278A/es not_active Application Discontinuation
- 2019-06-26 JP JP2020572645A patent/JP2021528456A/ja active Pending
- 2019-06-26 SG SG11202012784SA patent/SG11202012784SA/en unknown
- 2019-06-26 CR CR20210049A patent/CR20210049A/es unknown
- 2019-06-26 EA EA202190034A patent/EA202190034A1/ru unknown
- 2019-06-26 WO PCT/US2019/039156 patent/WO2020006031A1/en not_active Ceased
- 2019-06-26 ES ES19739494T patent/ES3032286T3/es active Active
- 2019-06-26 CA CA3104662A patent/CA3104662A1/en not_active Abandoned
-
2020
- 2020-12-23 CL CL2020003375A patent/CL2020003375A1/es unknown
- 2020-12-23 IL IL279709A patent/IL279709A/en unknown
-
2021
- 2021-01-25 CO CONC2021/0000782A patent/CO2021000782A2/es unknown
-
2023
- 2023-10-05 US US18/377,125 patent/US12404263B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20210115020A1 (en) | 2021-04-22 |
| IL279709A (en) | 2021-03-01 |
| US12404263B2 (en) | 2025-09-02 |
| CR20210049A (es) | 2021-07-01 |
| BR112020026423A2 (pt) | 2021-03-23 |
| EP3814333B1 (en) | 2025-03-19 |
| US20240109867A1 (en) | 2024-04-04 |
| MX2020013895A (es) | 2021-07-21 |
| CO2021000782A2 (es) | 2021-01-29 |
| TW202035389A (zh) | 2020-10-01 |
| EA202190034A1 (ru) | 2021-04-08 |
| WO2020006031A1 (en) | 2020-01-02 |
| AR115636A1 (es) | 2021-02-10 |
| KR20210024532A (ko) | 2021-03-05 |
| EP3814333A1 (en) | 2021-05-05 |
| WO2020006031A8 (en) | 2020-09-24 |
| AU2019291806A1 (en) | 2021-01-07 |
| SG11202012784SA (en) | 2021-01-28 |
| CL2020003375A1 (es) | 2021-09-03 |
| JP2021528456A (ja) | 2021-10-21 |
| UY38278A (es) | 2020-01-31 |
| ES3032286T3 (en) | 2025-07-16 |
| CA3104662A1 (en) | 2020-01-02 |
| US11814362B2 (en) | 2023-11-14 |
| CN112638896A (zh) | 2021-04-09 |
| PE20211379A1 (es) | 2021-07-27 |
| MA53009A (fr) | 2021-05-05 |
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