JOP20200323A1 - طرق لتصنيع تركيبات الأحماض الأمينية - Google Patents

طرق لتصنيع تركيبات الأحماض الأمينية

Info

Publication number
JOP20200323A1
JOP20200323A1 JOP/2020/0323A JOP20200323A JOP20200323A1 JO P20200323 A1 JOP20200323 A1 JO P20200323A1 JO P20200323 A JOP20200323 A JO P20200323A JO P20200323 A1 JOP20200323 A1 JO P20200323A1
Authority
JO
Jordan
Prior art keywords
methods
amino acid
acid compositions
manufacturing amino
manufacturing
Prior art date
Application number
JOP/2020/0323A
Other languages
English (en)
Inventor
Andrew M Wood
Thomas Hanlon
Ralph Yamamoto
Daniel Rothenberg
Denise K Kwok
Original Assignee
Axcella Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axcella Health Inc filed Critical Axcella Health Inc
Publication of JOP20200323A1 publication Critical patent/JOP20200323A1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

يوفر الكشف الحالي طرق لتصنيع مستحضرات ممزوجة واسعة النطاق تشتمل على واحد أو أكثر من الأحماض الأمينية حيث يكون للمستحضرات خواص معينة.
JOP/2020/0323A 2018-06-20 2019-06-19 طرق لتصنيع تركيبات الأحماض الأمينية JOP20200323A1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862687725P 2018-06-20 2018-06-20

Publications (1)

Publication Number Publication Date
JOP20200323A1 true JOP20200323A1 (ar) 2020-12-14

Family

ID=67226342

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2020/0323A JOP20200323A1 (ar) 2018-06-20 2019-06-19 طرق لتصنيع تركيبات الأحماض الأمينية

Country Status (17)

Country Link
US (1) US11679089B2 (ar)
EP (1) EP3810168A1 (ar)
JP (1) JP2021529735A (ar)
KR (1) KR20210023846A (ar)
CN (1) CN112823018A (ar)
AR (1) AR115581A1 (ar)
AU (1) AU2019288371A1 (ar)
BR (1) BR112020025831A2 (ar)
CA (1) CA3099762A1 (ar)
CL (1) CL2020003277A1 (ar)
IL (1) IL279328A (ar)
JO (1) JOP20200323A1 (ar)
MA (1) MA52957A (ar)
MX (1) MX2020013732A (ar)
SG (1) SG11202011611XA (ar)
TW (1) TW202015668A (ar)
WO (1) WO2019246201A1 (ar)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
US11617731B2 (en) 2017-04-28 2023-04-04 Axcella Health, Inc. Amino acid compositions and their use for the treatment of traumatic brain injury
IL296055A (en) 2017-08-14 2022-10-01 Axcella Health Inc Amino acid compositions for the treatment of liver disease
MA52971A (fr) 2018-06-20 2021-04-28 Axcella Health Inc Compositions et procédés pour le traitement de l'infiltration de graisse dans le muscle
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
CN112823018A (zh) 2018-06-20 2021-05-18 胺细拉健康公司 制备氨基酸组合物的方法
WO2023009444A1 (en) 2021-07-26 2023-02-02 Axcella Health Inc. Amino acid compositions and methods for use in the treatment of post-acute sequelae of covid-19
NL2038264B1 (en) * 2024-07-18 2025-03-06 West China Hospital Sichuan Univ Compound nutritional preparation for reducing fat and increasing muscle and preparation method thereof

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871550A (en) * 1986-09-05 1989-10-03 Millman Phillip L Nutrient composition for athletes and method of making and using the same
WO1994014458A1 (en) 1992-12-23 1994-07-07 Abbott Laboratories Medical foods for the nutritional support of infant/toddler metabolic diseases
US5922766A (en) * 1997-07-02 1999-07-13 Acosta; Phyllis J. B. Palatable elemental medical food
EP0891719A1 (en) 1997-07-14 1999-01-20 N.V. Nutricia Nutritional composition containing methionine
US20010041187A1 (en) 1998-10-20 2001-11-15 Carl W Hastings Performance-enhancing dietary supplement
WO2003041698A1 (fr) * 2001-11-13 2003-05-22 Kyowa Hakko Kogyo Co., Ltd. Comprimes contenant des acides amines se desintegrant rapidement dans la cavite buccale et procede de fabrication de ces comprimes
DE04759123T1 (de) 2003-04-07 2005-08-18 Novetide Ltd. Verfahren zur herstellung cyclischer peptide
US20040213838A1 (en) 2003-04-24 2004-10-28 Mazer Terrence B. Medical food tablets containing free amino acids
EP1699458A4 (en) 2003-12-30 2012-04-25 Reddys Lab Ltd Dr PHARMACEUTICAL COMPOSITION
US20060073254A1 (en) 2004-10-04 2006-04-06 Steve Catani No-carb tabletop sweeteners substitute
EP1839502A4 (en) 2004-12-07 2010-03-24 Ajinomoto Kk FINE AMINO ACID POWDER AND SUSPENSION THEREOF
US20070286909A1 (en) * 2006-06-07 2007-12-13 Daniel S. Smith Amino acid compositions
WO2011043647A1 (en) * 2009-10-09 2011-04-14 N.V. Nutricia Amino acid composition with improved dispersibility
JP2012136492A (ja) 2010-12-25 2012-07-19 Shiga Prefecture Seiyaku Kk 服用感を改善された漢方内服液剤
WO2015002527A1 (en) * 2013-07-05 2015-01-08 N.V. Nutricia Amino acid composition for use in the treatment of a pdd
WO2015015149A1 (en) 2013-07-31 2015-02-05 Leeds Metropolitan University Dietary supplement
US20180125926A1 (en) 2013-09-25 2018-05-10 Axcella Health Inc. Compositions and Formulations and Methods of Production and Use Thereof
EP3048904A2 (en) 2013-09-25 2016-08-03 Pronutria Biosciences, Inc. Compositions and formulations for treatment of gastrointestinal tract malabsorption diseases and inflammatory conditions and methods of production and use thereof
FR3032883B1 (fr) 2015-02-24 2017-03-17 International Nutrition Res Company Composition pour la prevention et le traitement de la steatose et de la steatohepatite metaboliques
JO3543B1 (ar) * 2015-09-28 2020-07-05 Applied Pharma Res تراكيب حمض أميني إصدار معدل تعطى عن طريق الفم
CA3012837A1 (en) * 2016-02-04 2017-08-10 Czap Research And Development, Llc Controlled-release and stratified cyclodextrin inclusion complex vehicles
PL238958B1 (pl) * 2016-06-29 2021-10-25 Olimp Laboratories Spolka Z Ograniczona Odpowiedzialnoscia Kompozycja aminokwasowa do stosowania przed wysiłkiem fizycznym
US20180015122A1 (en) 2016-07-14 2018-01-18 Companion Supplements, LLC Pharmaceutical composition effective in preventing adverse effects associated with the use of glucocorticoids
JOP20190147A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض واضطرابات العضلات
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
JP2018154598A (ja) 2017-03-21 2018-10-04 株式会社明治 アミノ酸含有顆粒およびその製造方法
US11617731B2 (en) 2017-04-28 2023-04-04 Axcella Health, Inc. Amino acid compositions and their use for the treatment of traumatic brain injury
WO2019036442A1 (en) 2017-08-14 2019-02-21 Axcella Health Inc. AMINO ACIDS BRANCHED FOR THE TREATMENT OF NEURONAL INJURY
IL296055A (en) 2017-08-14 2022-10-01 Axcella Health Inc Amino acid compositions for the treatment of liver disease
CN112689508A (zh) 2018-06-20 2021-04-20 胺细拉健康公司 减少或治疗胰岛素抗性和代谢病状的组合物和方法
JOP20200324A1 (ar) 2018-06-20 2020-12-14 Axcella Health Inc تركيبات للعلاج والصحة تحتوي على أحماض أمينية ذات طعم مُر
WO2019246298A1 (en) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions and methods for the reduction or treatment of fibrosis
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
WO2019246221A1 (en) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions and methods for the treatment of liver diseases and disorders
WO2019246310A1 (en) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions and methods for the reduction or treatment of inflammation
CN112823018A (zh) 2018-06-20 2021-05-18 胺细拉健康公司 制备氨基酸组合物的方法
MA52971A (fr) 2018-06-20 2021-04-28 Axcella Health Inc Compositions et procédés pour le traitement de l'infiltration de graisse dans le muscle

Also Published As

Publication number Publication date
US20190388374A1 (en) 2019-12-26
AR115581A1 (es) 2021-02-03
BR112020025831A2 (pt) 2021-03-23
MA52957A (fr) 2021-04-28
US11679089B2 (en) 2023-06-20
SG11202011611XA (en) 2021-01-28
JP2021529735A (ja) 2021-11-04
AU2019288371A1 (en) 2020-12-03
CN112823018A (zh) 2021-05-18
CA3099762A1 (en) 2019-12-26
KR20210023846A (ko) 2021-03-04
TW202015668A (zh) 2020-05-01
MX2020013732A (es) 2021-02-26
CL2020003277A1 (es) 2021-07-09
IL279328A (en) 2021-01-31
WO2019246201A1 (en) 2019-12-26
EP3810168A1 (en) 2021-04-28

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