JP2000247809A - Mite control method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an excellent mite control effect by using benzyl alcohol, and to control odors by benzyl alcohol within a range not to be uncomfortable, and to control mite comfortably. I will provide a. SOLUTION: The tick controlling method of the present invention is characterized in that benzyl alcohol is evaporated in a gas phase in a predetermined space, and the benzyl alcohol concentration in the gas phase is maintained at 0.1 to 10 ppm.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for controlling ticks, and more particularly, to a method for controlling ticks which has no odor or unpleasant chemical odor and has an excellent control effect on indoor dust mites.

[0002]

2. Description of the Related Art In recent years, breeding of house mites, particularly house dust mites, which are often present in house dust, causing allergic diseases has become a problem in ordinary households. Various insecticides are effective against blood-sucking mites, but most of these insecticides are not effective against mites that cause allergic diseases as described above. Group "19
Written in March 1995, "Allergy and living environment".

[0003] Slightly organophosphorus compounds, carbamate compounds and pyrethroid compounds are known as acaricides, and some of them are used in Europe and the United States, and pyrethroid compounds are also used in Japan.

Also, studies on acaricides with low toxicity to the human body have been actively conducted, and those using plant essential oils derived from natural products have been reported as being highly safe and capable of controlling mites widely. (JP-A-63-104905). The above-mentioned plant essential oil is used to control indoor ticks by evaporating.

[0005] However, when a natural essential oil component having an acaricide action is used in a living space, there is a problem that it is unpleasant due to an unpleasant odor or an excessively strong odor.

[0006]

DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned problems, exhibits excellent mite control effect by using benzyl alcohol, and controls the odor caused by benzyl alcohol within a range not to be uncomfortable. It is an object of the present invention to provide a method for controlling mites which can control mites.

[0007]

DISCLOSURE OF THE INVENTION The present inventors have found benzyl alcohol as a substance having particularly high acaricidal and low odor properties from natural essential oil components having acaricidal activity and its main components. However, benzyl alcohol alone releases a low-odor but unpleasant chemical odor. For this reason, by adjusting the benzyl alcohol vaporized gas concentration and controlling the chemical odor within a range that is not unpleasant, it is possible to effectively eliminate mites that live in the space, and in this space, people can enjoy daily life. They recognized that they did not feel uncomfortable even when they operated, and completed the present invention.

That is, the method for controlling ticks of the present invention is characterized in that benzyl alcohol is vaporized in a gas phase in a predetermined space, and the benzyl alcohol concentration in the gas phase is maintained at 0.1 to 10 ppm. .

Further, in the first aspect of the present invention, by using benzyl alcohol as a sustained-release material in which a liquid carrier or a solid carrier is impregnated, the concentration of the vaporized gas can be easily adjusted, and mite control can be performed more practically. It became clear that we could do that.

The concentration of benzyl alcohol in the gas phase is 0.1
If it is less than ppm, it will not be possible to exterminate the mite even if it has been exposed for a long time, but if the concentration is 0.1 ppm or more, it will be possible to exterminate the mite almost completely within 20 days. or,
If the concentration exceeds 10 ppm, the chemical odor is strong, and people living daily in the space feel discomfort.

Although it is difficult to adjust the benzyl alcohol concentration to 10 ppm or less by spontaneous evaporation, when the carrier having a large surface area is impregnated with benzyl alcohol as a sustained-release material, the vaporized gas concentration is maintained at 10 ppm or less. It is easy to control and mite can be almost completely eliminated by exposure for 5 days.

The exposure period can be arbitrarily set by selecting the concentration of benzyl alcohol in the predetermined space within the range of 0.1 to 10 ppm, but from the viewpoint of acaricidal effect and ease of use. It is preferred to select a concentration that results in an exposure period of between 5 and 20 days.

In the present invention, in order to enhance the acaricidal effect by a synergistic effect, a natural essential oil having acaricidal properties or a component purified as a single component from a natural essential oil is used in combination within a range that does not cause discomfort due to the odor of benzyl alcohol. No problem.

The natural essential oil components having acaricidal properties include mint oil, cassia oil, almond bitter oil, column oil, peppermint oil, spearmint oil, cinnamon oil, allspice oil, clove oil, thyme oil, and rosemary oil. , Lemongrass oil, lemon oil, yuzu oil, lime oil, apple aroma oil, grapefruit oil, sweet orange oil, navel oil, sweetie oil, valencia orange oil, mandarin oil, bergamot oil, laurel oil, star anise oil,
Sweet fennel oil, marjoram oil, mace oil, boad rose oil, palmarosa oil, lemon verbena oil, lemon balm oil, lavender oil, rose oil, eucalyptus oil, tea tree oil, ylang ylang oil, vetiver oil, pachiyouri oil, cananga oil, kagetput oil , Citronella oil, nutmeg oil, pepper oil, sandalwood oil, bulk oil,
Carzine oil, ginger oil, campo oil, cucumber oil, corn mint oil, anise oil, lang oil, cinnamon oil, mace oil, paromarosa oil, fennel oil, thyme oil, neem oil, laurel oil, laurel oil, sword oil, etc. No.

Examples of those purified as a single component from natural essential oils include menthol, mentone, limonene, citral, citronellal, citronellol, geraniol, cinnamaldehyde, eugenol, anethole, α-pinene, β-pinene, phenylethyl Alcohol and the like.

Various bactericides, fungicides, insect repellents, deodorants, and coloring agents may be added to benzyl alcohol.
Fungicides include benzalkonium chloride, benzethonium chloride, alkyltrimethylammonium chloride, resorcinol, phenol, sorbic acid, salicylic acid, hexachlorophene, and fungicides such as 2,4,4'-trichloro2'-hydroxydiphenyl ether. And
These are effective for controlling fungi such as Aspergillus, Penicillium, Ketomium and the like.

Examples of the insect repellent include N, N-diethyl-meta-toluamide, 2,3,4,5-bis (d2-butylene) -tetrahydrofural and lemongrass. Examples include methacrylate and various flavonoids. Preservatives include methyl p-oxybenzoate and ethyl p-oxybenzoate, and coloring agents include Red No. 2, Blue No. 1, Red No. 202, and Red 201.
Dyes, green dye No. 204, purple dye No. 201, etc., aluminum powder, and inorganic dyes such as talc, kaolin, bentonite, mica, titanium, red iron and calamine.

In the present invention, benzyl alcohol can be applied as it is as a mite control agent containing the above components, but usually the liquid or solid carrier holds the control agent and, if necessary, a solvent, an emulsifier and a dispersant. Agent, base,
By using propellants and sustained release agents, oils, emulsions, wettable powders, sprays (aerosols), sustained release agents (liquid, powder,
It can be used in the form of (granular), a smoke agent, a heat evaporation agent and the like.

The propellants include Freon 11, Freon 12, Freon 21, Freon 22, Freon 113, Freon 114,
Methyl chloride, isobutane, carbon dioxide, liquefied petroleum gas, dimethyl ether and the like are used.

Among the forms of the mite control agent, the form of a sustained release agent utilizing transpiration is particularly suitable. Usually, the sustained-release agent is maintained by dispersing or impregnating a liquid or solid carrier with a mite control agent mainly composed of benzyl alcohol.

Among the above-mentioned carriers impregnated with the tick controlling agent, the liquid carrier may be any as long as it can disperse the tick controlling agent as a liquid. Examples of the solvent include alcohols such as ethyl alcohol and isopropyl alcohol, acetone, methyl ethyl ketone and the like. Ketones, THF, dioxane, ethers such as diethyl ether, normal paraffin,
Aliphatic hydrocarbons such as solvent naphtha, aromatic hydrocarbons such as benzene and toluene, dichloroethane and the like, or soaps, polyoxyethylene fatty acid alcohol ethers, polyoxyethylene fatty acid esters, polyoxyethylene alkyl allyl ethers, fatty acid glycedes as solvents ,
It is adjusted by mixing and stirring a tick controlling agent with a surfactant such as sorbitan fatty acid ester, sulfate of higher alcohol, alkyl allyl sulfonic acid and the like.

In the case of a solid carrier, any material may be used as long as it has a gap for holding benzyl alcohol and other compounds and has a large surface area. The material thereof is a synthetic resin sheet such as polypropylene, animal or plant material or inorganic fiber material sheet ( Paper, cloth, nonwoven fabric, leather, etc.) alone or as a mixture. The form of the carrier is preferably a blended fabric, a nonwoven fabric using long fibers or short fibers, or the like.

As the solid carrier, there is a solid carrier which is suitable for controlling the sustained release when adsorbent inorganic compound particles and the like are used as an adsorbent. Such materials include, for example, silicic acid, silicic anhydride, titania, alumina, zirconia, magnesia, talc, kaolin, silica / alumina, silica / zirconia, silica / magnesia, silica / titania, and tantalum oxide Is mentioned.

In order to impregnate the carrier with benzyl alcohol, mineral spirits, mineral terpenes, solvent naphtha, terpene oils, various alcohols, ethers and water may be used as solvents and dispersants.

Further, sustained release is achieved by loading on a sublimable carrier such as tricyclodecane, cyclododecane, 2,4,6-triisopropyl-1,3,5-trioxane, trimethylnorbornene, paradichlorobenzene, naphthalene or camphor. Sex can also be adjusted.

The mites to be subjected to the method of controlling mites of the present invention are organisms of the order Arthropod-Arachnida-Acari, and are divided into the following seven sub-families. That is, the back respiratory tract represented by the red ticks, the four reticulate typified by the ticks, the red stomach represented by the ticks, the red stomach represented by the swallow sick mite, the mid stomach represented by the red mite, the spider mite, the stag beetle, represented by the mites mite. It is a respiratory tract represented by Rumazen genital mite, Dermatophagoides farinae, Dermatophagoides farinae, and a respiratory tract typified by house sarcophagus mites and mosquito mites. Although any of the above types can be a target, the main targets are Dermatophagoides and Dermatophagoides, which are particularly abundant in bedding and cause allergic diseases.

The place where the method for controlling mites of the present invention is carried out includes a closed space having a certain ventilation rate, for example, a clothes box, a clothes chest, a closet, an entrance space, a clog box and the like.

(Action) According to the tick control method of the present invention,
Since the vaporized gas of benzyl alcohol having high acaricidal and low odor properties is maintained at 0.1 to 10 ppm in the gas phase in a predetermined space, it suppresses off-odors and unpleasant chemical odors caused by benzyl alcohol, The required period can be arbitrarily adjusted.

Further, by using benzyl alcohol as a sustained-release material in which a liquid carrier or a solid carrier is impregnated, it is easy to control the concentration of benzyl alcohol within the above range.

[0030]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The embodiments of the present invention will be described below in detail. Test mite: Dermatophagoides pter
onyssinus) ♀ Adults were used. (Examples 1 to 5, Comparative Examples 1 and 2) Benzyl alcohol was used at the concentrations shown in Table 1 to evaluate the acaricidal effect. Preparation of Test Mite Container A glass microfiber filter paper having a diameter of 70 mm is folded in two, and two side portions are clipped to form a bag. The adult selected from the test mite medium is wetted using a moistened brush. Thirty individuals were introduced from the opening of the filter paper bag, and 10 mg of a mixture of mouse feed and dry yeast mixed at a ratio of 1: 1 was introduced as a bait from above, and the opening was clipped to provide a test mite container. .

Preparation of Experimental Vessel A petri dish containing 5 ml of a saturated saline solution for adjusting humidity was placed in a glass bottle having an internal volume of 500 ml, and one bag of test mite containers prepared in the above was placed on another petri dish. .

Installation of Benzyl Alcohol When benzyl alcohol was evaporated in the above-mentioned experimental container, it was weighed so as to have each of the concentrations shown in Table 1 and impregnated in glass filter paper. The container was placed in an experimental container, and the mouth of the container was covered with a lid made of polyethylene with a resin film interposed therebetween, and sealed with waterproof tape without any gap.

Tick count After 1 to 22 days, the test mite container is taken out, air-dried in clean air for 1 hour, and dried at 25 ° C. and 75% RH for 1 hour.
After allowing to stand for 8 hours, the filter paper was opened and the life and death of the mites were confirmed by a stereoscopic microscope. On the other hand, in order to confirm whether the operation of the experiment affected the test mites, a test mite container for control was prepared simultaneously with the test mite container used for the experiment (n =
3), it was stored in an experimental container not provided with benzyl alcohol, and used as a control.

Judgment of Effect Using the average value of the mite survival rate in each test plot (X ₁ ) and the average value of the tick survival rate in the control plot (X ₀ ), the corrected mortality (Y ) Was calculated, and the results are shown in Table 1. Y (%) = {(X ₀ −X ₁ ) / X ₀ } × 100 The average value of the corrected mortality of the three test mite containers was defined as the acaricidal rate. Table 1 shows the results.

[0035]

[Table 1]

(Example 6, Comparative Examples 3 and 4) The carrier was impregnated with benzyl alcohol to obtain a sustained-release material, and the concentration of benzyl alcohol when used in a garment box (made of polypropylene, inner volume of 100 liters) was determined. It was measured by the following method.

Preparation of sustained release material Kraft paper (5 cm ×
5 cm, a thickness of 2 mm, and a basis weight of 0.1 g / cm ² ) were impregnated with benzyl alcohol in an amount shown in Table 2 to produce a sustained-release material.

Each sustained-release material prepared in the measurement of the concentration was placed in a separate above-mentioned clothes box, the active ingredient in the gas phase was adsorbed on the adsorbent, and a calibration curve was prepared by gas chromatography and quantified. . Table 2 shows the results.

[0039]

[Table 2]

(Examples 7 to 9 and Comparative Example 5) In order to evaluate the odor, the carrier was impregnated so that the concentration of benzyl alcohol in the gas phase when installed in a closet was as shown in Table 3. The object was placed in a closet of a general household and a sensory test was performed.

Preparation of benzyl alcohol impregnated carrier Kraft paper (5 cm × 5 cm, 2 mm thick,
Weight per unit area 0.1 g / cm ^Two) Impregnated with benzyl alcohol
did. When the impregnation amount is set in the closet, the gas phase concentration is displayed.
Adjustment was performed so as to obtain the predetermined density shown in FIG.

Each of the benzyl alcohol-impregnated carriers prepared by the sensory test method was 5
At the general house at the eaves, it was installed in the center of the upper surface of the inside of the closet. A questionnaire survey was conducted on the results of living for one week including raising and lowering the futon, and the obtained responses were totaled according to the points shown in Table 3, and each benzyl The evaluation was made based on the total score for each alcohol concentration (a total score of 0 or more was regarded as a level without problems). Table 4 shows the evaluation results.

[0043]

[Table 3]

[0044]

[Table 4]

(Examples 7 to 9, Comparative Example 5) The following test was conducted to examine the effect of suppressing the increase of mites. Preparation of Test Mite Container A glass microfiber filter paper having a diameter of 70 mm was folded in two, and two sides were clipped to form a bag, and approximately 100 individuals and 1 adult selected from the test mite medium
0 individuals were put in through the opening of the filter paper bag using a moistened face brush, and 100 mg of a mixture of mouse feed and dry yeast mixed at a ratio of 1: 1 was put into the opening, and 100 mg was put in the opening. The test mite container was fastened with a clip.

Preparation of Experimental Vessel A petri dish containing 5 ml of a saturated saline solution for adjusting humidity was placed in a glass bottle having an internal volume of 500 liters.
One bag of the test mite container prepared in the above was placed on another petri dish and set.

Installation of mite control agent When benzyl alcohol was evaporated in the above-mentioned glass bottle, it was weighed so as to have the concentration shown in Table 4 and impregnated in glass filter paper, and this was put into a new petri dish and made. The container was placed in an experimental container, a polyethylene film lid was fastened to the mouth of the container with a resin film interposed therebetween, and the container was hermetically sealed with waterproof tape without any gap. Number of samples n = 5 for each concentration
And

Tick Count After 30 days had elapsed, the test mite container was taken out, air-dried in clean air for 1 hour, allowed to stand at 25 ° C. and 75% RH for 18 hours, and then the filter paper was opened to remove saturated saline. The number of surviving mites was examined by the water suspension method. On the other hand, in order to confirm the normal increase of ticks, a test mite container for control was prepared at the same time as the test mite container used for the experiment, and stored in an experimental container without benzyl alcohol as a control. The number n of the samples was also set to 5.

Judgment of Effect Using the average value (x ₁ ) of the number of live mites in each test group and the average value (x ₀ ) of the number of live mites in the control group, the rate of increase of the mite at each concentration was determined by the following equation. (Y) was calculated, and the results are shown in Table 5. y (%) = {(x ₀ −x ₁ ) / x ₀ } × 100

[0050]

[Table 5] (Note: The concentration that can suppress the increase of ticks by 50% or more was defined as the effective concentration.)

According to Table 4, it is considered that there is a boundary concentration between the benzyl alcohol concentrations of 0.1 ppm and 0.05 ppm, which indicates whether the increase of ticks can be suppressed.

[0052]

According to the method for controlling acarids of the present invention, the vaporized gas of benzyl alcohol having high acaricide and low odor is maintained at 0.1 to 10 ppm in the gas phase in a predetermined space. The unpleasant odor and unpleasant chemical odor due to alcohol can be controlled within a range that is not unpleasant, and even if a person performs daily life in the space, he does not feel unpleasant. In addition, mites living in the space can be effectively exterminated or suppressed from increasing. Furthermore, by using benzyl alcohol as a sustained-release material in which a liquid carrier or a solid carrier is impregnated, it becomes easy to control the concentration of benzyl alcohol within the above range.

 ────────────────────────────────────────────────── ─── Continuing on the front page (72) Inventor Satoshi Tamaki 2-1 Hyakuyama, Shimamoto-cho, Mishima-gun, Osaka Prefecture Sekisui Chemical Co., Ltd. F term (reference) 4H011 AC04 BB03 DA02 DA13 DA14 DA16 DA21 DB04 DD05 DD06 DE15 DG03 DG08

Claims (2)

[Claims] 1. A method for controlling ticks, wherein benzyl alcohol is vaporized in a gas phase in a predetermined space, and the benzyl alcohol concentration in the gas phase is maintained at 0.1 to 10 ppm. 2. The method according to claim 1, wherein the liquid carrier or the solid carrier is impregnated with benzyl alcohol as a sustained-release material.