JP2000506852A - シクロオキシゲナーゼの阻害剤としてのメルカプト誘導体 - Google Patents
シクロオキシゲナーゼの阻害剤としてのメルカプト誘導体Info
- Publication number
- JP2000506852A JP2000506852A JP9531871A JP53187197A JP2000506852A JP 2000506852 A JP2000506852 A JP 2000506852A JP 9531871 A JP9531871 A JP 9531871A JP 53187197 A JP53187197 A JP 53187197A JP 2000506852 A JP2000506852 A JP 2000506852A
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- group
- independently
- alkenylene
- formulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 18
- 229910052760 oxygen Inorganic materials 0.000 claims description 17
- GAPFINWZKMCSBG-UHFFFAOYSA-N 2-(2-sulfanylethyl)guanidine Chemical compound NC(=N)NCCS GAPFINWZKMCSBG-UHFFFAOYSA-N 0.000 claims description 16
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 15
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- IRMTXMJNHRISQH-UHFFFAOYSA-N 2-[2-[2-(diaminomethylideneamino)ethyldisulfanyl]ethyl]guanidine Chemical compound NC(N)=NCCSSCCN=C(N)N IRMTXMJNHRISQH-UHFFFAOYSA-N 0.000 claims description 7
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61109796A | 1996-03-05 | 1996-03-05 | |
| US08/611,097 | 1996-03-05 | ||
| PCT/US1997/003279 WO1997032575A1 (en) | 1996-03-05 | 1997-03-03 | Mercapto derivatives as inhibitors of cyclooxygenases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000506852A true JP2000506852A (ja) | 2000-06-06 |
Family
ID=24447614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9531871A Pending JP2000506852A (ja) | 1996-03-05 | 1997-03-03 | シクロオキシゲナーゼの阻害剤としてのメルカプト誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP2000506852A (pt) |
| CN (1) | CN1212620A (pt) |
| AU (1) | AU2063397A (pt) |
| BR (1) | BR9707953A (pt) |
| TR (1) | TR199801731T2 (pt) |
| WO (1) | WO1997032575A1 (pt) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516939A (ja) * | 2011-04-29 | 2014-07-17 | コリアナ リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー | オレアノール酸アセテートを有効成分として含むｔｌｒ及びｉｌ−６媒介性疾患の予防又は治療用の薬学的組成物 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999020110A1 (en) * | 1997-10-22 | 1999-04-29 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardio- and cerebrovascular disease |
| CH700523A1 (de) * | 2009-03-09 | 2010-09-15 | Markus Luethy | Neue Hautaufheller. |
| US9505829B2 (en) | 2010-08-19 | 2016-11-29 | Zoetis Belgium S.A. | Anti-NGF antibodies and their use |
| CN119410039A (zh) * | 2025-01-06 | 2025-02-11 | 浙江佳洁塑胶有限公司 | 一种多功能阻燃新型防滑垫的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5246971A (en) * | 1991-12-16 | 1993-09-21 | Washington University | Method of inhibiting nitric oxide formation |
| GB9200114D0 (en) * | 1992-01-04 | 1992-02-26 | Scras | Dual inhibitors of no synthase and cyclooxygenase |
| US5929063A (en) * | 1995-03-24 | 1999-07-27 | Children's Hospital Medical Center | Mercapto and seleno derivatives as inhibitors of nitric oxide synthase |
-
1997
- 1997-03-03 CN CN97192848A patent/CN1212620A/zh active Pending
- 1997-03-03 WO PCT/US1997/003279 patent/WO1997032575A1/en not_active Ceased
- 1997-03-03 AU AU20633/97A patent/AU2063397A/en not_active Abandoned
- 1997-03-03 JP JP9531871A patent/JP2000506852A/ja active Pending
- 1997-03-03 TR TR1998/01731T patent/TR199801731T2/xx unknown
- 1997-03-03 BR BR9707953-7A patent/BR9707953A/pt not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516939A (ja) * | 2011-04-29 | 2014-07-17 | コリアナ リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー | オレアノール酸アセテートを有効成分として含むｔｌｒ及びｉｌ−６媒介性疾患の予防又は治療用の薬学的組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997032575A1 (en) | 1997-09-12 |
| AU2063397A (en) | 1997-09-22 |
| TR199801731T2 (xx) | 1999-02-22 |
| BR9707953A (pt) | 2000-10-24 |
| CN1212620A (zh) | 1999-03-31 |
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