JP2000511537A - 黄色ブドウ球菌における毒力因子の発現の阻止 - Google Patents
黄色ブドウ球菌における毒力因子の発現の阻止Info
- Publication number
- JP2000511537A JP2000511537A JP09542779A JP54277997A JP2000511537A JP 2000511537 A JP2000511537 A JP 2000511537A JP 09542779 A JP09542779 A JP 09542779A JP 54277997 A JP54277997 A JP 54277997A JP 2000511537 A JP2000511537 A JP 2000511537A
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- cys
- cooh
- aureus
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 239000006228 supernatant Substances 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
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- 230000001018 virulence Effects 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
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- 241000766754 Agra Species 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Electrotherapy Devices (AREA)
- Air Conditioning Control Device (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Heat Treatment Of Steel (AREA)
- Control Of Combustion (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65122696A | 1996-05-22 | 1996-05-22 | |
| US08/651,226 | 1996-05-22 | ||
| PCT/US1997/008791 WO1997044349A1 (en) | 1996-05-22 | 1997-05-22 | BLOCKING EXPRESSION OF VIRULENCE FACTORS IN $i(S. AUREUS) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000511537A true JP2000511537A (ja) | 2000-09-05 |
Family
ID=24612055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09542779A Ceased JP2000511537A (ja) | 1996-05-22 | 1997-05-22 | 黄色ブドウ球菌における毒力因子の発現の阻止 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0932613B1 (de) |
| JP (1) | JP2000511537A (de) |
| AT (1) | ATE290548T1 (de) |
| AU (1) | AU735283B2 (de) |
| CA (1) | CA2256465A1 (de) |
| DE (1) | DE69732709T2 (de) |
| PT (1) | PT932613E (de) |
| WO (1) | WO1997044349A1 (de) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014221774A (ja) * | 2007-10-25 | 2014-11-27 | ザ スクリプス リサーチ インスティテュート | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2020536494A (ja) * | 2017-08-31 | 2020-12-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9724859D0 (en) * | 1997-11-26 | 1998-01-21 | Univ Nottingham | Compounds and their use as antibacterial agents |
| US7323179B2 (en) | 1997-12-19 | 2008-01-29 | Naomi Balaban | Methods and compositions for the treatment and prevention of Staphylococcus and other bacterial infections |
| US6291431B1 (en) | 1997-12-19 | 2001-09-18 | Panorama Research | Methods and compositions for the treatment and prevention of Staphylococcal infections |
| US7534857B2 (en) | 1997-12-19 | 2009-05-19 | Centegen, Inc. | Methods and compositions for the treatment and prevention of staphylococcal infections |
| CA2331888A1 (en) * | 1998-06-24 | 1999-12-29 | The Rockefeller University | Novel staphylococcus peptides for bacterial interference |
| US6337385B1 (en) | 1998-06-24 | 2002-01-08 | The Rockefeller University | Staphylococcus peptides for bacterial interference |
| EP1188831B1 (de) * | 1998-09-15 | 2007-12-05 | Naomi Balaban | Ziel des RNAIII activierenden Proteines (TRAP) |
| EP1862549A3 (de) | 1998-09-15 | 2008-02-13 | Naomi Balaban | Target eines RNAIII-aktivierenden Proteins (TRAP) |
| US6747129B1 (en) | 1998-09-15 | 2004-06-08 | The Regents Of The University Of California | Target of RNAIII activating protein(TRAP) |
| JP2003522153A (ja) * | 2000-02-10 | 2003-07-22 | インターミューン インコーポレイテッド | ブドウ球菌属ビルレンスの新規アミノ酸インヒビターおよびペプチドインヒビター |
| AU2001234147A1 (en) * | 2000-02-23 | 2001-09-03 | Kureha Chemical Industry Co. Ltd. | Plant growth promoters and method of promoting plant growth |
| US7824691B2 (en) | 2005-04-04 | 2010-11-02 | Centegen, Inc. | Use of RIP in treating staphylococcus aureus infections |
| ES2682595T3 (es) | 2015-03-23 | 2018-09-21 | Eberhard Karls Universität Tübingen | Nuevo compuesto antiinfeccioso |
| US10821167B2 (en) * | 2016-02-02 | 2020-11-03 | Unm Rainforest Innovations | VLP-based vaccines for targeting Staphylococcus aureus secreted virulence factors |
| KR102286075B1 (ko) * | 2019-09-27 | 2021-08-05 | 코스맥스 주식회사 | 스타필로코커스 렌투스 st-2 균주 및 그의 피부 상태 개선 용도 |
| KR102195998B1 (ko) * | 2019-09-27 | 2020-12-29 | 코스맥스 주식회사 | 스타필로코커스 시뮬란스 st-9 균주 및 그의 피부 상태 개선 용도 |
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| CN118931767B (zh) * | 2024-07-24 | 2025-03-25 | 内蒙古医科大学附属医院(内蒙古自治区心血管研究所) | 一株纹带棒状杆菌nmgcs43及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3825995A (en) * | 1994-10-04 | 1996-04-26 | New York University | Blocking expression of virulence factors in s. aureus |
-
1997
- 1997-05-22 JP JP09542779A patent/JP2000511537A/ja not_active Ceased
- 1997-05-22 AU AU32117/97A patent/AU735283B2/en not_active Ceased
- 1997-05-22 PT PT97927727T patent/PT932613E/pt unknown
- 1997-05-22 CA CA002256465A patent/CA2256465A1/en not_active Abandoned
- 1997-05-22 AT AT97927727T patent/ATE290548T1/de not_active IP Right Cessation
- 1997-05-22 EP EP97927727A patent/EP0932613B1/de not_active Expired - Lifetime
- 1997-05-22 DE DE69732709T patent/DE69732709T2/de not_active Expired - Fee Related
- 1997-05-22 WO PCT/US1997/008791 patent/WO1997044349A1/en not_active Ceased
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014221774A (ja) * | 2007-10-25 | 2014-11-27 | ザ スクリプス リサーチ インスティテュート | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2018021021A (ja) * | 2007-10-25 | 2018-02-08 | ザ スクリプス リサーチ インスティテュート | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2020536494A (ja) * | 2017-08-31 | 2020-12-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| JP7373176B2 (ja) | 2017-08-31 | 2023-11-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| JP2024009974A (ja) * | 2017-08-31 | 2024-01-23 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| JP7720639B2 (ja) | 2017-08-31 | 2025-08-08 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
| JP7720639B6 (ja) | 2017-08-31 | 2025-09-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 皮膚の酵素活性を制御する分子的細菌療法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0932613A4 (de) | 2002-01-09 |
| ATE290548T1 (de) | 2005-03-15 |
| PT932613E (pt) | 2005-06-30 |
| WO1997044349A1 (en) | 1997-11-27 |
| DE69732709T2 (de) | 2006-06-29 |
| EP0932613A1 (de) | 1999-08-04 |
| AU3211797A (en) | 1997-12-09 |
| CA2256465A1 (en) | 1997-11-27 |
| AU735283B2 (en) | 2001-07-05 |
| EP0932613B1 (de) | 2005-03-09 |
| DE69732709D1 (de) | 2005-04-14 |
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