JP2000516463A5 - - Google Patents

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Publication number
JP2000516463A5
JP2000516463A5 JP1998509392A JP50939298A JP2000516463A5 JP 2000516463 A5 JP2000516463 A5 JP 2000516463A5 JP 1998509392 A JP1998509392 A JP 1998509392A JP 50939298 A JP50939298 A JP 50939298A JP 2000516463 A5 JP2000516463 A5 JP 2000516463A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1998509392A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516463A (ja
Filing date
Publication date
Priority claimed from DE19632532A external-priority patent/DE19632532A1/de
Application filed filed Critical
Publication of JP2000516463A publication Critical patent/JP2000516463A/ja
Publication of JP2000516463A5 publication Critical patent/JP2000516463A5/ja
Withdrawn legal-status Critical Current

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JP10509392A 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法 Withdrawn JP2000516463A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632532.3 1996-08-13
DE19632532A DE19632532A1 (de) 1996-08-13 1996-08-13 Verfahren zur Herstellung von Säugetieren mit definierten genetischen Eigenschaften
PCT/EP1997/004352 WO1998006834A1 (fr) 1996-08-13 1997-08-09 Procede d'obtention de mammiferes presentant des proprietes genetiques definies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006218386A Division JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Publications (2)

Publication Number Publication Date
JP2000516463A JP2000516463A (ja) 2000-12-12
JP2000516463A5 true JP2000516463A5 (fr) 2005-04-07

Family

ID=7802466

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10509392A Withdrawn JP2000516463A (ja) 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Country Status (9)

Country Link
US (1) US6492575B1 (fr)
EP (1) EP0928332B1 (fr)
JP (2) JP2000516463A (fr)
AT (1) ATE281516T1 (fr)
CA (1) CA2263729C (fr)
DE (2) DE19632532A1 (fr)
ES (1) ES2231883T3 (fr)
PT (1) PT928332E (fr)
WO (1) WO1998006834A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
CN1083687C (zh) * 1999-02-15 2002-05-01 湖南师范大学 四倍体鱼的培育方法
JP2003533675A (ja) * 2000-03-28 2003-11-11 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 血小板由来成長因子ｃ（ｐｄｇｆ−ｃ）を発現する非ヒトトランスジェニック動物およびそれらの使用
US6784336B2 (en) 2000-09-20 2004-08-31 Whitehead Institute For Biomedical Research Method of producing mutant mice
JP4087338B2 (ja) * 2001-11-15 2008-05-21 キリンファーマ株式会社 キメラ非ヒト動物
JP4364474B2 (ja) 2002-02-15 2009-11-18 大学共同利用機関法人情報・システム研究機構 哺乳動物において機能的なトランスポゾン
US7365182B2 (en) * 2002-05-01 2008-04-29 Michigan State University Plant vernalization independence (VIP) genes, proteins, and methods of use
GB0210539D0 (en) * 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7723565B2 (en) * 2004-01-07 2010-05-25 Wisconsin Alumni Research Foundation Vernalization-related molecules and methods for inducibly-conferring epigenetic changes
EP2064325B1 (fr) 2006-09-01 2011-12-07 Therapeutic Human Polyclonals, Inc. Expression renforcée d'immunoglobuline humaine ou humanisée chez des animaux transgéniques non humains
TWI492951B (zh) 2007-12-31 2015-07-21 Baxter Int 表現人類凝血因子的基因轉殖非人類動物及其用途
NZ592905A (en) 2008-10-27 2012-11-30 Baxter Int Models of thrombotic thrombocytopenic purpura and methods of use thereof
US20120178158A1 (en) * 2009-06-23 2012-07-12 The Scripps Research Institute Adult animals generated from induced pluripotent cells
US20110072524A1 (en) 2009-08-04 2011-03-24 Baxter International Inc. Transgenic Mouse Lacking Endogenous FVIII and VWF - A Model of Hemophilia A
CN103025884B (zh) 2010-07-26 2015-11-25 特里安尼公司 转基因动物和使用方法
US10662256B2 (en) 2010-07-26 2020-05-26 Trianni, Inc. Transgenic mammals and methods of use thereof
US10793829B2 (en) 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
WO2015013575A2 (fr) * 2013-07-25 2015-01-29 Ingenious Targeting Laboratory, Inc. Souris knockout obtenues à partir d'une recombinase spécifique de site
EP3384030A4 (fr) 2015-12-03 2019-07-03 Trianni, Inc. Diversité améliorée d'immunoglobulines
EP4414484A3 (fr) 2016-02-04 2025-01-15 Trianni, Inc. Production améliorée d'immunoglobulines
CA3092832A1 (fr) * 2018-03-02 2019-09-06 Generation Bio Co. Identification et caracterisation de zones de securite du genome (gsh) chez les etres humains et les genomes murins, et compositions de vecteurs viraux et non viraux pour une inte gration ciblee au niveau d'un locus gsh identifie
WO2021174742A1 (fr) * 2020-03-06 2021-09-10 生物岛实验室 Procédé de préparation d'un animal
US20240374761A1 (en) 2021-05-05 2024-11-14 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
CN115466718B (zh) * 2022-08-09 2023-07-14 广州明迅生物科技有限责任公司 雌性胚胎干细胞及其制备方法和应用
CN118185862B (zh) * 2024-05-16 2024-08-09 中国科学院昆明动物研究所 一种小鼠四倍体器官的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
DE4228162C1 (de) * 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
US6331406B1 (en) 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use

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