JP2002255902A5 - - Google Patents
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- Publication number
- JP2002255902A5 JP2002255902A5 JP2001050020A JP2001050020A JP2002255902A5 JP 2002255902 A5 JP2002255902 A5 JP 2002255902A5 JP 2001050020 A JP2001050020 A JP 2001050020A JP 2001050020 A JP2001050020 A JP 2001050020A JP 2002255902 A5 JP2002255902 A5 JP 2002255902A5
- Authority
- JP
- Japan
- Prior art keywords
- chloride
- optically active
- phenylacetyl
- phenylacetic acid
- acid chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013543 active substance Substances 0.000 description 2
- -1 1-p-toluyl-phenyl 1-substituted phenyl-phenylacetyl chloride Chemical class 0.000 description 1
- VMZCDNSFRSVYKQ-UHFFFAOYSA-N 2-phenylacetyl chloride Chemical compound ClC(=O)CC1=CC=CC=C1 VMZCDNSFRSVYKQ-UHFFFAOYSA-N 0.000 description 1
- FOTITZRWZUAVPH-UHFFFAOYSA-N 2-phenylpropanoyl chloride Chemical compound ClC(=O)C(C)C1=CC=CC=C1 FOTITZRWZUAVPH-UHFFFAOYSA-N 0.000 description 1
- ASNHGEVAWNWCRQ-UHFFFAOYSA-N 4-(hydroxymethyl)oxolane-2,3,4-triol Chemical compound OCC1(O)COC(O)C1O ASNHGEVAWNWCRQ-UHFFFAOYSA-N 0.000 description 1
- FVOJFNWPSHEJEB-UHFFFAOYSA-N C1C=CC=CC1(CC2=CC=CC=C2)CC(=O)Cl Chemical compound C1C=CC=CC1(CC2=CC=CC=C2)CC(=O)Cl FVOJFNWPSHEJEB-UHFFFAOYSA-N 0.000 description 1
- PQHZNNUZUIRTIX-UHFFFAOYSA-N CCOC1(CC=CC=C1)CC(=O)Cl Chemical compound CCOC1(CC=CC=C1)CC(=O)Cl PQHZNNUZUIRTIX-UHFFFAOYSA-N 0.000 description 1
- IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 description 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 description 1
- 239000012346 acetyl chloride Substances 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 229960002510 mandelic acid Drugs 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
Description
このような光学活性カルボン酸クロリドの具体例としては、1−メチルフェニル酢酸クロリド等の1−アルキルフェニル酢酸クロリド類、1−エトキシフェニル酢酸クロリド等の1−アルコキシフェニル酢酸クロリド類、1−ホルミルオキシフェニル酢酸クロリド等のO−アシルマンデル酸クロリド類、1−p-トルイルフェニル酢酸クロリド等の1−置換フェニルフェニル酢酸クロリド類、1−ベンジルフェニル酢酸クロリド等の1−アラルキルフェニル酢酸クロリド類の光学活性体を挙げることができる。ここで、光学活性体とは、(R)体、(S)体の何れの光学活性体も含むが、光学純度は98%ee以上である。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001050020A JP4873207B2 (ja) | 2001-02-26 | 2001-02-26 | 光学活性カルボン酸クロリドの精製方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001050020A JP4873207B2 (ja) | 2001-02-26 | 2001-02-26 | 光学活性カルボン酸クロリドの精製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002255902A JP2002255902A (ja) | 2002-09-11 |
| JP2002255902A5 true JP2002255902A5 (ja) | 2008-03-27 |
| JP4873207B2 JP4873207B2 (ja) | 2012-02-08 |
Family
ID=18911044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001050020A Expired - Lifetime JP4873207B2 (ja) | 2001-02-26 | 2001-02-26 | 光学活性カルボン酸クロリドの精製方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4873207B2 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150016133A (ko) | 2013-08-02 | 2015-02-11 | 주식회사 엘지화학 | 광반응성 화합물의 정제 방법 및 광반응성 화합물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928592A (en) * | 1974-02-22 | 1975-12-23 | Lilly Co Eli | Antibiotic pharmaceutical compositions |
| JPS6450840A (en) * | 1987-08-21 | 1989-02-27 | Nippon Oils & Fats Co Ltd | Method for purifying acyl halide |
| JP3010816B2 (ja) * | 1991-08-22 | 2000-02-21 | ダイセル化学工業株式会社 | 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法 |
| JP3959777B2 (ja) * | 1997-04-10 | 2007-08-15 | 日本油脂株式会社 | カルボン酸クロリドの製造方法 |
| JP2000247943A (ja) * | 1999-02-23 | 2000-09-12 | Mitsui Chemicals Inc | 光学活性n−カルボニルアミノ酸エステルの製造法 |
-
2001
- 2001-02-26 JP JP2001050020A patent/JP4873207B2/ja not_active Expired - Lifetime
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