JP2004000251A5 - - Google Patents

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Publication number: JP2004000251A5
Authority: JP; Japan
Prior art keywords: amino acid; acid sequence; compound; compound according; human ghrelin
Prior art date: 2003-07-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP2003271241A

Other languages

English (en)

Japanese (ja)

Other versions

JP4227857B2 (ja

JP2004000251A (ja

Filing date

2003-07-07

Publication date

2007-09-06

2003-07-07 Application filed filed Critical

2003-07-07 Priority to JP2003271241A priority Critical patent/JP4227857B2/ja

2003-07-07 Priority claimed from JP2003271241A external-priority patent/JP4227857B2/ja

2004-01-08 Publication of JP2004000251A publication Critical patent/JP2004000251A/ja

2007-09-06 Publication of JP2004000251A5 publication Critical patent/JP2004000251A5/ja

2009-02-18 Application granted granted Critical

2009-02-18 Publication of JP4227857B2 publication Critical patent/JP4227857B2/ja

2020-07-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 claims 22
125000003275 alpha amino acid group Chemical group 0.000 claims 15
108090000765 processed proteins & peptides Proteins 0.000 claims 12
GNKDKYIHGQKHHM-RJKLHVOGSA-N ghrelin Chemical compound C([C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CN)COC(=O)CCCCCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C1=CC=CC=C1 GNKDKYIHGQKHHM-RJKLHVOGSA-N 0.000 claims 11
150000001413 amino acids Chemical class 0.000 claims 2
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 1
101800001586 Ghrelin Proteins 0.000 claims 1
102000012004 Ghrelin Human genes 0.000 claims 1
229910001424 calcium ion Inorganic materials 0.000 claims 1
230000000694 effects Effects 0.000 claims 1
230000003834 intracellular effect Effects 0.000 claims 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
150000003839 salts Chemical class 0.000 claims 1
238000006467 substitution reaction Methods 0.000 claims 1

JP2003271241A 1999-07-23 2003-07-07 新規ペプチド Expired - Lifetime JP4227857B2 (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP2003271241A JP4227857B2 (ja)	1999-07-23	2003-07-07	新規ペプチド

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP21000299		1999-07-23
JP33884199		1999-11-29
JP2000126623		2000-04-26
JP2003271241A JP4227857B2 (ja)	1999-07-23	2003-07-07	新規ペプチド

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2001512558A Division JP3471780B2 (ja)	1999-07-23	2000-07-24	新規ペプチド

Publications (3)

Publication Number	Publication Date
JP2004000251A JP2004000251A (ja)	2004-01-08
JP2004000251A5 true JP2004000251A5 (2)	2007-09-06
JP4227857B2 JP4227857B2 (ja)	2009-02-18

Family

ID=27329078

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
JP2001512558A Expired - Lifetime JP3471780B2 (ja)	1999-07-23	2000-07-24	新規ペプチド
JP2003271241A Expired - Lifetime JP4227857B2 (ja)	1999-07-23	2003-07-07	新規ペプチド

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
JP2001512558A Expired - Lifetime JP3471780B2 (ja)	1999-07-23	2000-07-24	新規ペプチド

Country Status (16)

Country	Link
US (5)	US7385026B1 (2)
EP (3)	EP1795598B1 (2)
JP (2)	JP3471780B2 (2)
KR (1)	KR100827973B1 (2)
CN (2)	CN101693736B (2)
AT (2)	ATE449174T1 (2)
AU (2)	AU784035B2 (2)
BR (2)	BR0012688A (2)
CA (2)	CA2696819C (2)
CY (2)	CY1107724T1 (2)
DE (2)	DE60043361D1 (2)
DK (2)	DK1795598T3 (2)
ES (3)	ES2401939T3 (2)
IL (2)	IL147652A0 (2)
PT (2)	PT1795598E (2)
WO (1)	WO2001007475A1 (2)

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JPWO2007058360A1 (ja) *	2005-11-21	2009-05-07	国立大学法人宮崎大学	デスアシルグレリン及びその誘導体を有効成分とする皮膚修復促進治療剤
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CA2660517A1 (en)	2006-08-11	2008-02-14	University Of Miyazaki	Spinal nerve repair promoting therapeutics containing ghrelin or its derivatives or substances that act on ghs-rla as an active ingredient
US8299022B2 (en) *	2006-09-27	2012-10-30	Ipsen Pharma S.A.S.	Analogs of ghrelin substituted at the N-terminal
KR101350251B1 (ko)	2008-05-23	2014-01-14	다이이찌 산쿄 가부시키가이샤	목적 펩타이드의 혈장내 반감기 연장 작용을 가진 펩타이드
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JP6057314B2 (ja)	2010-01-15	2017-01-11	国立大学法人宮崎大学	加療中動物の回復促進治療剤
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2000
- 2000-07-24 ES ES09166974T patent/ES2401939T3/es not_active Expired - Lifetime
- 2000-07-24 CN CN200910141231.3A patent/CN101693736B/zh not_active Expired - Lifetime
- 2000-07-24 BR BR0012688-8A patent/BR0012688A/pt not_active IP Right Cessation
- 2000-07-24 ES ES00946453T patent/ES2288151T3/es not_active Expired - Lifetime
- 2000-07-24 JP JP2001512558A patent/JP3471780B2/ja not_active Expired - Lifetime
- 2000-07-24 EP EP07006224A patent/EP1795598B1/en not_active Expired - Lifetime
- 2000-07-24 WO PCT/JP2000/004907 patent/WO2001007475A1/ja not_active Ceased
- 2000-07-24 AT AT07006224T patent/ATE449174T1/de active
- 2000-07-24 CA CA2696819A patent/CA2696819C/en not_active Expired - Lifetime
- 2000-07-24 BR BRPI0012688A patent/BRPI0012688B8/pt unknown
- 2000-07-24 ES ES07006224T patent/ES2335235T3/es not_active Expired - Lifetime
- 2000-07-24 EP EP09166974A patent/EP2119785B1/en not_active Expired - Lifetime
- 2000-07-24 KR KR1020027000758A patent/KR100827973B1/ko not_active Expired - Lifetime
- 2000-07-24 PT PT07006224T patent/PT1795598E/pt unknown
- 2000-07-24 US US09/959,577 patent/US7385026B1/en not_active Expired - Lifetime
- 2000-07-24 CA CA2380058A patent/CA2380058C/en not_active Expired - Lifetime
- 2000-07-24 IL IL14765200A patent/IL147652A0/xx unknown
- 2000-07-24 PT PT00946453T patent/PT1197496E/pt unknown
- 2000-07-24 CN CNB008104409A patent/CN100506844C/zh not_active Expired - Lifetime
- 2000-07-24 AT AT00946453T patent/ATE366813T1/de active
- 2000-07-24 EP EP00946453A patent/EP1197496B8/en not_active Expired - Lifetime
- 2000-07-24 DK DK07006224.5T patent/DK1795598T3/da active
- 2000-07-24 DK DK00946453T patent/DK1197496T3/da active
- 2000-07-24 DE DE60043361T patent/DE60043361D1/de not_active Expired - Lifetime
- 2000-07-24 AU AU60231/00A patent/AU784035B2/en not_active Expired
- 2000-07-24 DE DE60035502T patent/DE60035502T2/de not_active Expired - Lifetime
2002
- 2002-01-15 IL IL147652A patent/IL147652A/en active IP Right Grant
2003
- 2003-07-07 JP JP2003271241A patent/JP4227857B2/ja not_active Expired - Lifetime
2006
- 2006-04-13 AU AU2006201580A patent/AU2006201580B2/en not_active Expired
2007
- 2007-08-28 CY CY20071101137T patent/CY1107724T1/el unknown
2008
- 2008-01-30 US US12/010,838 patent/US8227570B2/en not_active Expired - Fee Related
2010
- 2010-01-05 CY CY20101100012T patent/CY1109714T1/el unknown
- 2010-03-22 US US12/728,495 patent/US9573986B2/en not_active Expired - Fee Related
2011
- 2011-03-31 US US13/076,844 patent/US8524871B2/en not_active Expired - Fee Related
2012
- 2012-06-12 US US13/494,673 patent/US9938332B2/en not_active Expired - Fee Related

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