JP2005290008A5 - - Google Patents

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Publication number
JP2005290008A5
JP2005290008A5 JP2005130614A JP2005130614A JP2005290008A5 JP 2005290008 A5 JP2005290008 A5 JP 2005290008A5 JP 2005130614 A JP2005130614 A JP 2005130614A JP 2005130614 A JP2005130614 A JP 2005130614A JP 2005290008 A5 JP2005290008 A5 JP 2005290008A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2005130614A
Other versions
JP2005290008A (ja
Filing date
Publication date
Priority claimed from US08/859,931 external-priority patent/US5945510A/en
Application filed filed Critical
Publication of JP2005290008A publication Critical patent/JP2005290008A/ja
Publication of JP2005290008A5 publication Critical patent/JP2005290008A5/ja
Withdrawn legal-status Critical Current

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JP2005130614A 1997-05-21 2005-04-27 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 Withdrawn JP2005290008A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/859,931 US5945510A (en) 1997-05-21 1997-05-21 Substantially pure zonulin, a physiological modulator of mammalian tight junctions

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP55036098A Division JP2001527572A (ja) 1997-05-21 1998-04-28 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Publications (2)

Publication Number Publication Date
JP2005290008A JP2005290008A (ja) 2005-10-20
JP2005290008A5 true JP2005290008A5 (ja) 2006-02-23

Family

ID=25332088

Family Applications (2)

Application Number Title Priority Date Filing Date
JP55036098A Ceased JP2001527572A (ja) 1997-05-21 1998-04-28 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子
JP2005130614A Withdrawn JP2005290008A (ja) 1997-05-21 2005-04-27 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP55036098A Ceased JP2001527572A (ja) 1997-05-21 1998-04-28 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Country Status (10)

Country Link
US (1) US5945510A (ja)
EP (1) EP0982988B1 (ja)
JP (2) JP2001527572A (ja)
AT (1) ATE250625T1 (ja)
AU (1) AU7249198A (ja)
CA (1) CA2290459A1 (ja)
DE (1) DE69818450T2 (ja)
DK (1) DK0982988T3 (ja)
ES (1) ES2209133T3 (ja)
WO (1) WO1998052415A1 (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908825A (en) * 1997-01-09 1999-06-01 University Of Maryland At Baltimore Dosage composition for nasal delivery and method of use of the same
US6458925B1 (en) * 1998-08-03 2002-10-01 University Of Maryland, Baltimore Peptide antagonists of zonulin and methods for use of the same
CN1221249C (zh) 1998-08-19 2005-10-05 斯凯伊药品加拿大公司 普鲁泊福的可注射水分散体
KR100615442B1 (ko) * 1998-09-14 2006-08-25 유니버시티 오브 메릴랜드, 볼티모어 항원-특이적 방식으로 림프구 증식을 저해하기 위한 조트또는 조눌린의 사용방법
US6733762B1 (en) 1998-09-14 2004-05-11 University Of Maryland, Baltimore Method of using Zot to inhibit lymphocyte proliferation in an antigen-specific manner
EP1221975B1 (en) 1999-10-04 2006-12-06 Nektar Therapeutics Al, Corporation Polymer stabilized neuropeptides
US7026294B2 (en) * 2000-05-19 2006-04-11 University Of Maryland Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes
US7034036B2 (en) * 2000-10-30 2006-04-25 Pain Therapeutics, Inc. Inhibitors of ABC drug transporters at the blood-brain barrier
EP1384468A1 (de) * 2002-07-25 2004-01-28 Cognis France S.A. Verfahren zum Schutz und zur Modulation von Tight Junctions
EP1384469A1 (de) * 2002-07-25 2004-01-28 Cognis France S.A. Verfahren zum Schutz und zur Modulation von Tight Junctions
CA2531491A1 (en) * 2003-07-15 2005-02-03 University Of Maryland, Baltimore Agonist polypeptide of receptor for zot and zonulin
US20080038843A1 (en) * 2006-08-11 2008-02-14 University Of Maryland - Baltimore Method of diagnosing celiac disease
TW200637573A (en) * 2005-01-14 2006-11-01 Univ Maryland Peptide for delivery of mucosal vaccines
TW200716159A (en) * 2005-06-09 2007-05-01 Univ Maryland Method of use of antagonists of zonulin to prevent the loss of or to regenerate pancreatic cells
AR060103A1 (es) * 2006-02-09 2008-05-28 Alba Therapeutics Corp Formulaciones para un efector de uniones apretadas
US20070239520A1 (en) * 2006-03-31 2007-10-11 Devin Collins Motivational apparatus and method of motivation
WO2008043107A2 (en) * 2006-10-06 2008-04-10 Alba Therapeutics Corporation Use of tight junction antagonists to treat inflammatory bowel disease
US8034776B2 (en) * 2006-10-26 2011-10-11 Alba Therapeutics Corporation Materials and methods for the treatment of celiac disease
US20100144646A1 (en) * 2006-11-03 2010-06-10 Blake Paterson Method of diagnosing and treating asthma
WO2009023311A2 (en) * 2007-05-07 2009-02-19 Alba Therapeutics Corporation Transcutaneous delivery of therapeutic agents
WO2009006246A1 (en) * 2007-06-29 2009-01-08 Alea Therapeutics Corp. Use of tight junction antagonists in the treatment of acute long injury and acute respiratory distress syndrome
WO2009015382A2 (en) 2007-07-26 2009-01-29 Alba Therapeutics Corporation Novel peptides that enhance tight junction permeability
KR102236462B1 (ko) 2012-03-19 2021-04-08 시다라 세라퓨틱스, 인코포레이티드 에키노칸딘 계열의 화합물에 대한 투여 용법
JP6760657B2 (ja) * 2015-05-26 2020-09-23 国立大学法人東海国立大学機構 タイトジャンクションの緩和剤、該緩和剤を含む薬剤吸収補助剤、及び該緩和剤を含む医薬組成物
JP2020507626A (ja) 2017-02-10 2020-03-12 イノベイト バイオファーマシューティカルズ インコーポレイテッド 腸上皮の透過性と関連する疾患を治療する組成物及び方法
US11608359B2 (en) 2018-02-23 2023-03-21 9 Meters Biopharma, Inc. Compounds and methods for treating tight junction permeabtility

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665389A (en) * 1995-05-24 1997-09-09 University Of Maryland At Baltimore Oral dosage composition for intestinal delivery and method of treating diabetes

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