JP2005509652A - 蛋白質の瘤 - Google Patents
蛋白質の瘤 Download PDFInfo
- Publication number
- JP2005509652A JP2005509652A JP2003542901A JP2003542901A JP2005509652A JP 2005509652 A JP2005509652 A JP 2005509652A JP 2003542901 A JP2003542901 A JP 2003542901A JP 2003542901 A JP2003542901 A JP 2003542901A JP 2005509652 A JP2005509652 A JP 2005509652A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- subunit
- knob
- cysteine
- hcg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34528301P | 2001-11-08 | 2001-11-08 | |
| PCT/US2002/035914 WO2003040695A2 (en) | 2001-11-08 | 2002-11-08 | Protein knobs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007265961A Division JP2008110973A (ja) | 2001-11-08 | 2007-10-11 | 蛋白質の瘤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2005509652A true JP2005509652A (ja) | 2005-04-14 |
Family
ID=23354368
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542901A Pending JP2005509652A (ja) | 2001-11-08 | 2002-11-08 | 蛋白質の瘤 |
| JP2007265961A Pending JP2008110973A (ja) | 2001-11-08 | 2007-10-11 | 蛋白質の瘤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007265961A Pending JP2008110973A (ja) | 2001-11-08 | 2007-10-11 | 蛋白質の瘤 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1497634A4 (no) |
| JP (2) | JP2005509652A (no) |
| KR (1) | KR20040063928A (no) |
| CN (1) | CN1596304A (no) |
| CA (1) | CA2466595A1 (no) |
| EA (1) | EA200400647A1 (no) |
| HR (1) | HRP20040242A2 (no) |
| IL (1) | IL161804A0 (no) |
| MX (1) | MXPA04004289A (no) |
| NO (1) | NO20042358L (no) |
| PL (1) | PL373566A1 (no) |
| WO (1) | WO2003040695A2 (no) |
| ZA (1) | ZA200404373B (no) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017508967A (ja) * | 2014-03-04 | 2017-03-30 | モロジック・リミテッドMologic Limited | アッセイ法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005263555B2 (en) * | 2004-07-16 | 2011-01-27 | Amgen Research (Munich) Gmbh | Expression-enhanced polypeptides |
| CN112986571B (zh) * | 2019-12-12 | 2023-04-11 | 中国科学院大连化学物理研究所 | 一种鉴定Midkine时空网络相互作用蛋白质的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0578328B1 (en) * | 1983-11-02 | 1999-12-29 | Applied Research Systems ARS Holding N.V. | Material and methods for the production of a heterodimeric human LH with a Met42 Val55 alpha subunit |
| ES2098261T3 (es) * | 1989-02-21 | 1997-05-01 | Univ Washington | Formas modificadas de hormonas reproductoras. |
| US5166322A (en) * | 1989-04-21 | 1992-11-24 | Genetics Institute | Cysteine added variants of interleukin-3 and chemical modifications thereof |
| WO1997004080A1 (en) * | 1995-07-14 | 1997-02-06 | Fuji Yakuhin Kogyo Kabushiki Kaisha | Novel protein and monoclonal antibody specific thereto |
| US6001354A (en) * | 1995-11-17 | 1999-12-14 | Washington University | GRB2 associating polypeptides and nucleic acids encoding therefor |
| US5837837A (en) * | 1997-02-27 | 1998-11-17 | Millennium Pharmaceuticals, Inc. | Nucleic acids molecules encoding Caspase-8h and Caspase-8i |
| SI0996629T1 (sl) * | 1997-06-25 | 2006-12-31 | Applied Research Systems | Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba |
-
2002
- 2002-11-08 HR HR20040242A patent/HRP20040242A2/hr not_active Application Discontinuation
- 2002-11-08 CN CNA02822101XA patent/CN1596304A/zh active Pending
- 2002-11-08 CA CA002466595A patent/CA2466595A1/en not_active Abandoned
- 2002-11-08 EP EP02789525A patent/EP1497634A4/en not_active Withdrawn
- 2002-11-08 KR KR10-2004-7006994A patent/KR20040063928A/ko not_active Ceased
- 2002-11-08 EA EA200400647A patent/EA200400647A1/ru unknown
- 2002-11-08 IL IL16180402A patent/IL161804A0/xx unknown
- 2002-11-08 JP JP2003542901A patent/JP2005509652A/ja active Pending
- 2002-11-08 MX MXPA04004289A patent/MXPA04004289A/es not_active Application Discontinuation
- 2002-11-08 WO PCT/US2002/035914 patent/WO2003040695A2/en not_active Ceased
- 2002-11-08 PL PL02373566A patent/PL373566A1/xx not_active Application Discontinuation
-
2004
- 2004-06-03 ZA ZA2004/04373A patent/ZA200404373B/en unknown
- 2004-06-07 NO NO20042358A patent/NO20042358L/no not_active Application Discontinuation
-
2007
- 2007-10-11 JP JP2007265961A patent/JP2008110973A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017508967A (ja) * | 2014-03-04 | 2017-03-30 | モロジック・リミテッドMologic Limited | アッセイ法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1596304A (zh) | 2005-03-16 |
| JP2008110973A (ja) | 2008-05-15 |
| PL373566A1 (en) | 2005-09-05 |
| MXPA04004289A (es) | 2005-03-31 |
| WO2003040695A3 (en) | 2004-11-11 |
| IL161804A0 (en) | 2005-11-20 |
| NO20042358L (no) | 2004-08-09 |
| EA200400647A1 (ru) | 2004-10-28 |
| CA2466595A1 (en) | 2003-05-15 |
| HRP20040242A2 (en) | 2005-02-28 |
| KR20040063928A (ko) | 2004-07-14 |
| EP1497634A2 (en) | 2005-01-19 |
| WO2003040695A2 (en) | 2003-05-15 |
| ZA200404373B (en) | 2005-11-30 |
| EP1497634A4 (en) | 2007-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4255618B2 (ja) | 単鎖二官能性糖タンパク質ホルモン | |
| JP4387625B2 (ja) | Her2に結合する化合物 | |
| US5958737A (en) | Single-chain β subunit dimers of the glycoprotein hormones and recombinant materials related thereto | |
| US6028177A (en) | Methods of detecting single-chain forms of the glycoprotein hormone quartet | |
| JPH07508178A (ja) | レセプター活性化 | |
| JP4278668B2 (ja) | ジスルフィド架橋結合した糖タンパク質ホルモン類似体類およびそれらの調製および使用 | |
| Moad et al. | Selective CGRP and adrenomedullin peptide binding by tethered RAMP‐calcitonin receptor‐like receptor extracellular domain fusion proteins | |
| EP0725795B1 (en) | Single-chain forms of the glycoprotein hormone quartet | |
| Cook et al. | Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line | |
| JP2008110973A (ja) | 蛋白質の瘤 | |
| US5883073A (en) | Single-chain double-alpha peptide | |
| US7442376B2 (en) | Glycoprotein hormone compositions containing two β subunits | |
| CA2394332A1 (en) | Chimeric neuropeptide y receptors | |
| US20060177894A1 (en) | Protein knobs | |
| JP2009050278A (ja) | 糖タンパク質ホルモンカルテットの一本鎖形態 | |
| AU2002352567A1 (en) | Protein knobs | |
| Xing et al. | Use of protein knobs to characterize the position of conserved α-subunit regions in lutropin receptor complexes | |
| Rooney et al. | Production of platelet-derived growth factor receptor (PDGFR-β) in E. coli: Mapping ligand binding domain | |
| WO2026010814A1 (en) | Methods and reagents for cell-based screening of genetically encoded protein binders | |
| CN116769015A (zh) | 一种牛IgG Fc受体boFcγRIII的线性配体结合表位 | |
| Oh | The structure and function ofhCG and the LH/CG receptor | |
| Fralish | Towards an understanding of luteinizing hormone receptor binding | |
| Stevis et al. | A glutathione-S-transferase-FSHα subunit hybrid associates with FSHβ, retains biological activity, and facilitates purification |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050928 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20050928 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20050928 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070411 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20070709 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20070717 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20070810 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20070817 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20070910 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20070918 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20071221 |