JP2006199633A5 - - Google Patents

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Publication number: JP2006199633A5
Authority: JP; Japan
Prior art keywords: composition; ceramide; external; vesicle; mass
Prior art date: 2005-01-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP2005013836A

Other languages

English (en)

Japanese (ja)

Other versions

JP4563194B2 (ja

JP2006199633A (ja

Filing date

2005-01-21

Publication date

2007-12-13

2005-01-21 Application filed filed Critical

2005-01-21 Priority to JP2005013836A priority Critical patent/JP4563194B2/ja

2005-01-21 Priority claimed from JP2005013836A external-priority patent/JP4563194B2/ja

2006-08-03 Publication of JP2006199633A publication Critical patent/JP2006199633A/ja

2007-12-13 Publication of JP2006199633A5 publication Critical patent/JP2006199633A5/ja

2010-10-13 Application granted granted Critical

2010-10-13 Publication of JP4563194B2 publication Critical patent/JP4563194B2/ja

2025-01-21 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

239000000203 mixture Substances 0.000 claims description 43
229940106189 ceramide Drugs 0.000 claims description 25
YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims description 24
CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims description 24
ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims description 24
VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims description 24
229930182470 glycoside Natural products 0.000 claims description 21
150000002338 glycosides Chemical class 0.000 claims description 21
235000002378 plant sterols Nutrition 0.000 claims description 21
239000002537 cosmetic Substances 0.000 claims description 15
150000003904 phospholipids Chemical class 0.000 claims description 14
239000003093 cationic surfactant Substances 0.000 claims description 8
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
239000002253 acid Substances 0.000 claims description 2
239000008103 glucose Substances 0.000 claims description 2
125000000217 alkyl group Chemical group 0.000 claims 2
125000004432 carbon atom Chemical group C* 0.000 claims 2
125000003342 alkenyl group Chemical group 0.000 claims 1
229910052500 inorganic mineral Inorganic materials 0.000 claims 1
239000011707 mineral Substances 0.000 claims 1
230000000052 comparative effect Effects 0.000 description 14
239000002245 particle Substances 0.000 description 9
LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 8
238000009472 formulation Methods 0.000 description 7
238000004062 sedimentation Methods 0.000 description 7
239000006185 dispersion Substances 0.000 description 6
241000894007 species Species 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 4
238000005119 centrifugation Methods 0.000 description 4
230000002349 favourable effect Effects 0.000 description 4
238000000034 method Methods 0.000 description 4
238000002156 mixing Methods 0.000 description 4
KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 4
229950005143 sitosterol Drugs 0.000 description 4
KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 3
CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 3
OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 3
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 3
KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 3
OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 3
LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 3
ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 3
MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 3
229940067606 lecithin Drugs 0.000 description 3
235000010445 lecithin Nutrition 0.000 description 3
239000000787 lecithin Substances 0.000 description 3
229940068065 phytosterols Drugs 0.000 description 3
235000015500 sitosterol Nutrition 0.000 description 3
NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 3
HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 3
235000016831 stigmasterol Nutrition 0.000 description 3
229940032091 stigmasterol Drugs 0.000 description 3
BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 3
WWUZIQQURGPMPG-UHFFFAOYSA-N (-)-D-erythro-Sphingosine Natural products CCCCCCCCCCCCCC=CC(O)C(N)CO WWUZIQQURGPMPG-UHFFFAOYSA-N 0.000 description 2
SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 description 2
235000005956 Cosmos caudatus Nutrition 0.000 description 2
AERBNCYCJBRYDG-UHFFFAOYSA-N D-ribo-phytosphingosine Natural products CCCCCCCCCCCCCCC(O)C(O)C(N)CO AERBNCYCJBRYDG-UHFFFAOYSA-N 0.000 description 2
244000068988 Glycine max Species 0.000 description 2
235000010469 Glycine max Nutrition 0.000 description 2
BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 description 2
ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 description 2
241000209094 Oryza Species 0.000 description 2
230000003110 anti-inflammatory effect Effects 0.000 description 2
239000008365 aqueous carrier Substances 0.000 description 2
235000000431 campesterol Nutrition 0.000 description 2
SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 description 2
235000014113 dietary fatty acids Nutrition 0.000 description 2
239000003814 drug Substances 0.000 description 2
229940079593 drug Drugs 0.000 description 2
229930195729 fatty acid Natural products 0.000 description 2
239000000194 fatty acid Substances 0.000 description 2
150000004665 fatty acids Chemical class 0.000 description 2
-1 glucoside Chemical class 0.000 description 2
125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 2
239000004973 liquid crystal related substance Substances 0.000 description 2
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 2
229940033329 phytosphingosine Drugs 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 2
230000008591 skin barrier function Effects 0.000 description 2
239000000344 soap Substances 0.000 description 2
WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 description 2
239000000126 substance Substances 0.000 description 2
235000013311 vegetables Nutrition 0.000 description 2
TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 description 1
JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical group CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 1
ZEHFBSPKWJAHQQ-KNOOOGQZSA-N C(CCCCCCCCCCCCCCCCC)(=O)N[C@@H](CO)[C@H](O)\C(=C(\CCCCCCCCCCCCC)/O)\O Chemical compound C(CCCCCCCCCCCCCCCCC)(=O)N[C@@H](CO)[C@H](O)\C(=C(\CCCCCCCCCCCCC)/O)\O ZEHFBSPKWJAHQQ-KNOOOGQZSA-N 0.000 description 1
241000255925 Diptera Species 0.000 description 1
102000002322 Egg Proteins Human genes 0.000 description 1
108010000912 Egg Proteins Proteins 0.000 description 1
241000196324 Embryophyta Species 0.000 description 1
102000004130 Fusion Regulatory Protein-1 Human genes 0.000 description 1
108010057784 Fusion Regulatory Protein-1 Proteins 0.000 description 1
JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 description 1
ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 description 1
SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical group C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
BBAFBDLICMHBNU-MFZOPHKMSA-N N-(2-hydroxyoctadecanoyl)-4-hydroxysphinganine Chemical compound CCCCCCCCCCCCCCCCC(O)C(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC BBAFBDLICMHBNU-MFZOPHKMSA-N 0.000 description 1
KZTJQXAANJHSCE-OIDHKYIRSA-N N-octodecanoylsphinganine Chemical compound CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC KZTJQXAANJHSCE-OIDHKYIRSA-N 0.000 description 1
235000007164 Oryza sativa Nutrition 0.000 description 1
LGJMUZUPVCAVPU-JFBKYFIKSA-N Sitostanol Natural products O[C@@H]1C[C@H]2[C@@](C)([C@@H]3[C@@H]([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)CC2)CC1 LGJMUZUPVCAVPU-JFBKYFIKSA-N 0.000 description 1
VBIIFPGSPJYLRR-UHFFFAOYSA-M Stearyltrimethylammonium chloride Chemical group [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)C VBIIFPGSPJYLRR-UHFFFAOYSA-M 0.000 description 1
229930182558 Sterol Natural products 0.000 description 1
241000209140 Triticum Species 0.000 description 1
235000021307 Triticum Nutrition 0.000 description 1
ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 description 1
230000000397 acetylating effect Effects 0.000 description 1
230000021736 acetylation Effects 0.000 description 1
238000006640 acetylation reaction Methods 0.000 description 1
AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 description 1
125000000089 arabinosyl group Chemical group C1([C@@H](O)[C@H](O)[C@H](O)CO1)* 0.000 description 1
SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 description 1
229940076810 beta sitosterol Drugs 0.000 description 1
239000003054 catalyst Substances 0.000 description 1
125000002091 cationic group Chemical group 0.000 description 1
150000001783 ceramides Chemical class 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000012459 cleaning agent Substances 0.000 description 1
238000004440 column chromatography Methods 0.000 description 1
239000008406 cosmetic ingredient Substances 0.000 description 1
230000006196 deacetylation Effects 0.000 description 1
238000003381 deacetylation reaction Methods 0.000 description 1
GQOKIYDTHHZSCJ-UHFFFAOYSA-M dimethyl-bis(prop-2-enyl)azanium;chloride Chemical compound [Cl-].C=CC[N+](C)(C)CC=C GQOKIYDTHHZSCJ-UHFFFAOYSA-M 0.000 description 1
230000000694 effects Effects 0.000 description 1
235000013345 egg yolk Nutrition 0.000 description 1
210000002969 egg yolk Anatomy 0.000 description 1
238000000605 extraction Methods 0.000 description 1
238000005194 fractionation Methods 0.000 description 1
229930182478 glucoside Natural products 0.000 description 1
150000008131 glucosides Chemical class 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
230000007774 longterm Effects 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
239000004530 micro-emulsion Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
150000008104 phosphatidylethanolamines Chemical class 0.000 description 1
150000003905 phosphatidylinositols Chemical class 0.000 description 1
AERBNCYCJBRYDG-KSZLIROESA-N phytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO AERBNCYCJBRYDG-KSZLIROESA-N 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
238000004321 preservation Methods 0.000 description 1
238000000746 purification Methods 0.000 description 1
235000009566 rice Nutrition 0.000 description 1
239000013049 sediment Substances 0.000 description 1
229910001923 silver oxide Inorganic materials 0.000 description 1
230000003381 solubilizing effect Effects 0.000 description 1
239000002904 solvent Substances 0.000 description 1
229940083466 soybean lecithin Drugs 0.000 description 1
125000002328 sterol group Chemical group 0.000 description 1
150000003432 sterols Chemical class 0.000 description 1
235000003702 sterols Nutrition 0.000 description 1
LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1

JP2005013836A 2005-01-21 2005-01-21 外用組成物 Expired - Fee Related JP4563194B2 (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP2005013836A JP4563194B2 (ja)	2005-01-21	2005-01-21	外用組成物

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2005013836A JP4563194B2 (ja)	2005-01-21	2005-01-21	外用組成物

Publications (3)

Publication Number	Publication Date
JP2006199633A JP2006199633A (ja)	2006-08-03
JP2006199633A5 true JP2006199633A5 (de)	2007-12-13
JP4563194B2 JP4563194B2 (ja)	2010-10-13

Family

ID=36957950

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2005013836A Expired - Fee Related JP4563194B2 (ja)	2005-01-21	2005-01-21	外用組成物

Country Status (1)

Country	Link
JP (1)	JP4563194B2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5109065B2 (ja) *	2006-10-04	2012-12-26	株式会社コーセー	ベシクル組成物、及びそれを用いた皮膚外用剤
JP5468385B2 (ja) *	2007-11-02	2014-04-09	ナガセケムテックス株式会社	抗真菌剤及び抗菌剤
JP5690074B2 (ja) *	2010-03-23	2015-03-25	日本精化株式会社	セラミド誘導体を含有する化粧料
JP2015017053A (ja) *	2013-07-10	2015-01-29	ポーラ化成工業株式会社	ベシクル分散組成物、該ベシクル分散組成物の製造方法、および該ベシクル分散組成物を含む皮膚外用剤
JP6092039B2 (ja) *	2013-08-02	2017-03-08	富士フイルム株式会社	乳化組成物
JP6723737B2 (ja) *	2015-12-12	2020-07-15	オリザ油化株式会社	皮膚におけるグルコシルセラミド生成及び代謝遺伝子発現促進剤
KR102164218B1 (ko) *	2019-09-24	2020-10-12	코스맥스 주식회사	피부 흡수 증진을 위한 다중층 양이온성 리포좀 및 이의 제조방법
IT202100003539A1 (it)	2021-02-16	2022-08-16	Unifarco S P A	Composizioni ad uso topico ottimizzate in lipidi epidermici e fosfatidilglicerolo

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Publication number	Priority date	Publication date	Assignee	Title
FR2673179B1 (fr) *	1991-02-21	1993-06-11	Oreal	Ceramides, leur procede de preparation et leurs applications en cosmetique et en dermopharmacie.
US5885613A (en) *	1994-09-30	1999-03-23	The University Of British Columbia	Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
JPH0987147A (ja) *	1995-09-22	1997-03-31	Noevir Co Ltd	毛髪用組成物
FR2742988B1 (fr) *	1996-01-03	1998-01-30	Oreal	Composition aqueuse contenant des vesicules lipidiques non-ioniques et au moins un pigment non-enrobe disperse dans la phase aqueuse, procede de preparation, utilisations
JP3817354B2 (ja) *	1998-01-12	2006-09-06	日本精化株式会社	スフィンゴ脂質−界面活性剤複合体
DE19854827A1 (de) *	1998-11-27	2000-06-08	Merz & Co Gmbh & Co	Vesikelbildende tensidhaltige Reinigungszubereitungen auf wäßriger Basis, Verfahren zu ihrer Herstellung sowie ihre Verwendung
EP1443108A3 (de) *	2003-01-30	2005-10-12	L'oreal	Verfahren zur Herstellung eines in Ceramid 7 und/oder 5.5 ergänzt Hautersatzes, Zusammensetzung aus lamellaren Lipidvesikeln, die ein Derivat von Ceramid 7 und/oder 5.5 enthalten, und Verwendung davon
JP2004352643A (ja) *	2003-05-29	2004-12-16	Kose Corp	ゲル状化粧料

2005
- 2005-01-21 JP JP2005013836A patent/JP4563194B2/ja not_active Expired - Fee Related

Publication	Publication Date	Title
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