JP2006506441A5 - - Google Patents
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- Publication number
- JP2006506441A5 JP2006506441A5 JP2004553936A JP2004553936A JP2006506441A5 JP 2006506441 A5 JP2006506441 A5 JP 2006506441A5 JP 2004553936 A JP2004553936 A JP 2004553936A JP 2004553936 A JP2004553936 A JP 2004553936A JP 2006506441 A5 JP2006506441 A5 JP 2006506441A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- box
- hmgb
- use according
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42784802P | 2002-11-20 | 2002-11-20 | |
| PCT/US2003/036975 WO2004046338A2 (en) | 2002-11-20 | 2003-11-19 | Use of hmgb polypeptides for increasing immune responses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006506441A JP2006506441A (ja) | 2006-02-23 |
| JP2006506441A5 true JP2006506441A5 (2) | 2006-12-28 |
Family
ID=32326601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004553936A Withdrawn JP2006506441A (ja) | 2002-11-20 | 2003-11-19 | 免疫応答を増大させるためのｈｍｇｂポリペプチドの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060121047A1 (2) |
| EP (1) | EP1567544A4 (2) |
| JP (1) | JP2006506441A (2) |
| AU (1) | AU2003295653B2 (2) |
| CA (1) | CA2505682A1 (2) |
| WO (1) | WO2004046338A2 (2) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
| US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| WO2005025604A2 (en) * | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Use of hmgb and hmgb fragments to decrease specific immune response |
| AU2004272607B2 (en) | 2003-09-11 | 2008-11-06 | Cornerstone Therapeutics Inc. | Monoclonal antibodies against HMGB1 |
| WO2006114805A2 (en) * | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
| US20090297546A1 (en) * | 2006-12-20 | 2009-12-03 | Shino-Test Corporation | Avian-derived antibody capable of binding specifically to human hmgb1, immunological determination method for human hmgb1, and immunological determination reagent for human hmgb1 |
| JP5225109B2 (ja) | 2007-02-15 | 2013-07-03 | 国立大学法人 熊本大学 | ヒトｈｍｇｂ−１に特異的に結合する抗体を有効成分として含有する治療剤 |
| US8227417B2 (en) * | 2008-07-25 | 2012-07-24 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | HMGN polypeptides as immune enhancers and HMGN antagonists as immune suppressants |
| ES2643646T3 (es) | 2010-01-21 | 2017-11-23 | The Board Of Trustees Of The University Of Arkansas | Vectores de vacuna y métodos para potenciar las respuestas inmunitarias |
| CN103097399A (zh) | 2010-03-29 | 2013-05-08 | 南加利福尼亚大学 | 用于去除生物膜的组合物及方法 |
| MX350306B (es) | 2010-06-09 | 2017-09-04 | Univ Arkansas | Vacuna y metodos para reducir una infeccion por campylobacter. |
| EP2613797B1 (en) | 2010-09-09 | 2015-11-04 | University Of Southern California | Compositions and methods for the removal of biofilms |
| AR094791A1 (es) | 2013-02-14 | 2015-08-26 | Univ Arkansas | Composiciones y métodos para mejorar las respuestas inmunes ante una infección por eimeria o para limitar una infección por eimeria |
| AU2014239557B2 (en) | 2013-03-15 | 2019-01-03 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US10233234B2 (en) | 2014-01-13 | 2019-03-19 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| EP3229813B1 (en) | 2014-12-12 | 2021-03-24 | The Feinstein Institute for Medical Research | Treatment of hmgb1-mediated inflammation |
| WO2017023863A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| CN108367049A (zh) | 2015-12-11 | 2018-08-03 | 海德堡吕布莱希特-卡尔斯大学 | Pkm2调节剂和hmgb1的组合制剂 |
| KR102767638B1 (ko) | 2016-05-03 | 2025-02-20 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법 |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| WO2018170178A1 (en) | 2017-03-15 | 2018-09-20 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| AU2019354829B2 (en) | 2018-10-05 | 2025-04-17 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms |
| WO2022243932A1 (en) * | 2021-05-19 | 2022-11-24 | Oxford University Innovation Limited | Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof |
| US20250101204A1 (en) * | 2022-02-28 | 2025-03-27 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for protecting against cell damage and inflammation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5605690A (en) * | 1989-09-05 | 1997-02-25 | Immunex Corporation | Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor |
| US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5656272A (en) * | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| GB9217316D0 (en) * | 1992-08-14 | 1992-09-30 | Ludwig Inst Cancer Res | Schwann cell mitogenic factor,its preparation and use |
| US6323329B1 (en) * | 1995-12-21 | 2001-11-27 | Jorn Bullerdiek | Nucleic acid sequences of genes encoding high mobility group proteins |
| US6171779B1 (en) * | 1996-07-12 | 2001-01-09 | University Of Medicine & Dentistry Of New Jersey | HMGI proteins in cancer |
| US6720472B2 (en) * | 1996-07-12 | 2004-04-13 | University Of Medicine And Dentistry Of New Jersey | HMGI proteins in cancer and obesity |
| DE69737870T2 (de) * | 1996-07-17 | 2008-02-07 | Kaneka Corp. | Medikamente für die diagnostik von autoimmunerkrankungen |
| US7151082B2 (en) * | 1999-02-11 | 2006-12-19 | The Feinstein Institute For Medical Research | Antagonists of HMG1 for treating inflammatory conditions |
| US6303321B1 (en) * | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| US6177077B1 (en) * | 1999-02-24 | 2001-01-23 | Edward L. Tobinick | TNT inhibitors for the treatment of neurological disorders |
| WO2001070663A2 (en) * | 2000-03-17 | 2001-09-27 | Corixa Corporation | Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors |
| US7304034B2 (en) * | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
| US7220723B2 (en) * | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| CN100447154C (zh) * | 2001-05-15 | 2008-12-31 | 费因斯坦医学研究学院 | 利用hmg片段作为抗炎症试剂 |
| US20030014155A1 (en) * | 2001-07-12 | 2003-01-16 | Applied Material, Inc. | High temperature substrate transfer robot |
-
2003
- 2003-11-19 US US10/535,267 patent/US20060121047A1/en not_active Abandoned
- 2003-11-19 EP EP03786854A patent/EP1567544A4/en not_active Withdrawn
- 2003-11-19 CA CA002505682A patent/CA2505682A1/en not_active Abandoned
- 2003-11-19 JP JP2004553936A patent/JP2006506441A/ja not_active Withdrawn
- 2003-11-19 AU AU2003295653A patent/AU2003295653B2/en not_active Ceased
- 2003-11-19 WO PCT/US2003/036975 patent/WO2004046338A2/en not_active Ceased
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