JP2007502806A5 - - Google Patents
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- Publication number
- JP2007502806A5 JP2007502806A5 JP2006523683A JP2006523683A JP2007502806A5 JP 2007502806 A5 JP2007502806 A5 JP 2007502806A5 JP 2006523683 A JP2006523683 A JP 2006523683A JP 2006523683 A JP2006523683 A JP 2006523683A JP 2007502806 A5 JP2007502806 A5 JP 2007502806A5
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- phenoxy
- phenyl
- acetic acid
- methylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0302281A SE0302281D0 (sv) | 2003-08-21 | 2003-08-21 | Novel compounds |
| SE0302281-1 | 2003-08-21 | ||
| GB0412448A GB0412448D0 (en) | 2004-06-04 | 2004-06-04 | Novel compounds |
| GB0412448.3 | 2004-06-04 | ||
| PCT/GB2004/003551 WO2005018529A2 (en) | 2003-08-21 | 2004-08-18 | Phenoxiacetic acid derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007502806A JP2007502806A (ja) | 2007-02-15 |
| JP2007502806A5 true JP2007502806A5 (2) | 2007-07-12 |
| JP5025264B2 JP5025264B2 (ja) | 2012-09-12 |
Family
ID=34219638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006523683A Expired - Fee Related JP5025264B2 (ja) | 2003-08-21 | 2004-08-18 | フェノキシ酢酸誘導体 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US8003703B2 (2) |
| EP (1) | EP1660431B1 (2) |
| JP (1) | JP5025264B2 (2) |
| KR (1) | KR101136175B1 (2) |
| AR (1) | AR045470A1 (2) |
| AT (1) | ATE427296T1 (2) |
| AU (1) | AU2004266485B2 (2) |
| BR (1) | BRPI0413490A (2) |
| CA (1) | CA2535714C (2) |
| CO (1) | CO5670367A2 (2) |
| CY (1) | CY1110318T1 (2) |
| DE (1) | DE602004020356D1 (2) |
| DK (1) | DK1660431T3 (2) |
| ES (1) | ES2322653T3 (2) |
| HR (1) | HRP20090280T1 (2) |
| IL (1) | IL173522A (2) |
| IS (1) | IS2693B (2) |
| MX (1) | MXPA06001954A (2) |
| MY (1) | MY142029A (2) |
| NZ (1) | NZ545450A (2) |
| PL (1) | PL1660431T3 (2) |
| PT (1) | PT1660431E (2) |
| RU (1) | RU2360901C2 (2) |
| SA (1) | SA04250253B1 (2) |
| SI (1) | SI1660431T1 (2) |
| TW (1) | TWI347313B (2) |
| UY (1) | UY28482A1 (2) |
| WO (1) | WO2005018529A2 (2) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| US7714132B2 (en) | 2004-03-11 | 2010-05-11 | Actelion Pharmaceuticals, Ltd. | Tetrahydropyridoindole derivatives |
| US20090105218A1 (en) * | 2004-05-29 | 2009-04-23 | 7Tm Pharma A/S | CRTH2 Receptor Ligands For Therapeutic Use |
| EP1758579A1 (en) * | 2004-05-29 | 2007-03-07 | 7TM Pharma A/S | Crth2 receptor ligands for medicinal uses |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
| GB0510585D0 (en) * | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| GB0510584D0 (en) * | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| DK1928457T3 (da) * | 2005-09-30 | 2013-02-04 | Pulmagen Therapeutics Asthma Ltd | Quinoliner og deres terapeutiske anvendelse |
| EP1937632A1 (en) | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| GB0520324D0 (en) * | 2005-10-06 | 2005-11-16 | Astrazeneca Ab | Novel compounds |
| TW200745003A (en) * | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| RU2424229C2 (ru) * | 2005-10-06 | 2011-07-20 | Астразенека Аб | Производные бифенилоксиуксусной кислоты, их применение для изготовления лекарственного средства и промежуточные соединения |
| EP1948630A2 (en) * | 2005-11-05 | 2008-07-30 | AstraZeneca AB | Novel compounds |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
| GB0524428D0 (en) | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
| TW200732296A (en) * | 2005-12-15 | 2007-09-01 | Astrazeneca Ab | Novel compounds |
| JP2009538289A (ja) | 2006-05-26 | 2009-11-05 | アストラゼネカ・アクチエボラーグ | ビアリールまたはヘテロアリール置換インドール |
| WO2007149312A2 (en) | 2006-06-16 | 2007-12-27 | The Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and bph |
| GB0702456D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
| CA2680682C (en) | 2007-04-04 | 2015-05-26 | Argenta Discovery Limited | Quinolines and their therapeutic use |
| UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| DK2229358T3 (da) | 2007-12-14 | 2011-07-04 | Pulmagen Therapeutics Asthma Ltd | Indoler og deres terapeutiske anvendelse |
| WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
| GB0818365D0 (en) * | 2008-10-07 | 2008-11-12 | Argenta Discovery Ltd | Quinoline compounds |
| BRPI0921038A2 (pt) * | 2008-11-17 | 2019-09-24 | Hoffmann La Roche | ácido naftilacéticos |
| HRP20141065T1 (hr) | 2009-07-09 | 2015-02-13 | Kyorin Pharmaceutical Co., Ltd. | Derivati difenil-sulfida i lijekovi koji ih sadrže kao aktivni sastojak |
| GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
| WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
| WO2011073662A1 (en) | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
| CN102958914B (zh) | 2010-07-05 | 2015-05-27 | 埃科特莱茵药品有限公司 | 1-苯基取代的杂环衍生物及其作为前列腺素d2受体调节剂的用途 |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
| GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
| EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
| EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
| EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
| SG11201402796SA (en) | 2011-12-16 | 2014-06-27 | Atopix Therapeutics Ltd | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| TW201331179A (zh) | 2011-12-21 | 2013-08-01 | Actelion Pharmaceuticals Ltd | 雜環衍生物及其作為前列腺素ｄ２受體調節劑之用途 |
| CN108938441A (zh) | 2012-03-21 | 2018-12-07 | 宾夕法尼亚大学理事会 | 用于调节毛发生长的组合物和方法 |
| CA2876808A1 (en) | 2012-07-05 | 2014-01-09 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| TW201623264A (zh) | 2014-03-29 | 2016-07-01 | 魯賓有限公司 | 作為電位閘控鈉通道調節劑之磺胺化合物 |
| JP6770522B2 (ja) | 2015-02-13 | 2020-10-14 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 全身性エリテマトーデスを予防し、及び／又は、治療するためのｐｔｇｄｒ−１及び／又はｐｔｇｄｒ−２アンタゴニスト |
| LT3305768T (lt) * | 2015-05-27 | 2020-08-25 | Jiangsu Hengrui Medicine Co., Ltd. | Šlapimo rūgšties natrio druskos transporterio inhibitorius ir jo kristalinė forma |
| MX2018001217A (es) | 2015-07-30 | 2018-09-12 | Univ Pennsylvania | Alelos polimorficos de nucleotidos individuales del gen humano dp-2 para la deteccion de la susceptibilidad a la inhibicion del crecimiento del cabello por pgd2. |
| WO2017097182A1 (zh) * | 2015-12-07 | 2017-06-15 | 成都海创药业有限公司 | 喹啉类化合物及其制备方法和作为尿酸盐转运体抑制剂类药物的用途 |
| GB201709396D0 (en) | 2017-06-13 | 2017-07-26 | Astrazeneca Ab | Compounds for use as radioligands |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB690816A (en) | 1950-01-02 | 1953-04-29 | British Drug Houses Ltd | Improvements in or relating to the manufacture of substituted phenoxy acetic acids |
| US3278524A (en) | 1962-03-13 | 1966-10-11 | Beecham Group Ltd | Penicillins and their production |
| CH432119A (de) * | 1963-02-22 | 1967-03-15 | Geigy Ag J R | Verwendung von Halogen-o-hydroxy-diphenyläthern als antimikrobielle Mittel |
| BE790679A (fr) | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
| DD113545A5 (2) | 1973-03-30 | 1975-06-12 | ||
| JPS5239888B2 (2) * | 1973-05-28 | 1977-10-07 | ||
| US3954852A (en) | 1973-10-19 | 1976-05-04 | Merck & Co., Inc. | Indenylacetic acid compounds |
| SE419538B (sv) | 1973-10-29 | 1981-08-10 | Eisai Co Ltd | Analogiforfaranden for framstellning av 2-(n-fenoxfenyl)-propionsyraderivat |
| CH582476A5 (2) * | 1973-10-29 | 1976-12-15 | Ciba Geigy Ag | |
| GB1585963A (en) * | 1976-10-14 | 1981-03-11 | Lilly Industries Ltd | Aryl sulphur compounds |
| US4248618A (en) | 1977-05-06 | 1981-02-03 | Ici Australia Limited | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof |
| DE2832435A1 (de) | 1977-07-27 | 1979-02-08 | Ciba Geigy Ag | Phenoxy-phenoxy-alkancarbonsaeurederivate |
| FR2428629A1 (fr) * | 1978-06-14 | 1980-01-11 | Hexachimie | Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique |
| JPS5951943B2 (ja) * | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
| GB2041363B (en) | 1979-01-19 | 1982-10-06 | Pfizer Ltd | N-benzyl-imidazoles |
| US4670566A (en) | 1979-07-12 | 1987-06-02 | A. H. Robins Company, Incorporated | 3-methyl-hio-4-(5-, 6-, or 7-)phenylindolindolin-2-ones |
| US4486593A (en) | 1983-01-19 | 1984-12-04 | The Upjohn Company | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors |
| DE3419009A1 (de) * | 1984-05-22 | 1985-11-28 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue substituierte bis(4-aminophenyl)sulfone, ihre herstellung und ihre verwendung als arzneimittel |
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| US5145790A (en) | 1990-05-04 | 1992-09-08 | Abbott Laboratories | Reagents and method for detecting polychlorinated biphenyls |
| EP0540165A1 (en) | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
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| JPH06313995A (ja) | 1993-04-28 | 1994-11-08 | Hodogaya Chem Co Ltd | 静電荷像現像用トナー |
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| CA2219269A1 (en) | 1996-10-29 | 1998-04-29 | Novartis Ag | Novel herbicides |
| FR2763588B1 (fr) | 1997-05-23 | 1999-07-09 | Cird Galderma | Composes triaromatiques, compositions les contenant et utilisations |
| CO4960662A1 (es) | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
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| US6417212B1 (en) | 1999-08-27 | 2002-07-09 | Eli Lilly & Company | Modulators of peroxisome proliferator activated receptors |
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| JP2003523336A (ja) | 2000-02-18 | 2003-08-05 | メルク エンド カムパニー インコーポレーテッド | 糖尿病及び脂質障害のためのアリールオキシ酢酸 |
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| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| JP2004501191A (ja) | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
| US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
| US20040097555A1 (en) | 2000-12-26 | 2004-05-20 | Shinegori Ohkawa | Concomitant drugs |
| WO2002094770A2 (en) | 2001-05-24 | 2002-11-28 | Fujisawa Pharmaceutical Co., Ltd. | Aminoalcohol derivatives |
| EP1395257A1 (en) | 2001-06-12 | 2004-03-10 | Elan Pharmaceuticals, Inc. | Macrocycles useful in the treatment of alzheimer's disease |
| CA2459515A1 (en) | 2001-09-07 | 2003-03-20 | Kazuhiko Torisu | Indole derivatives |
| RU2337909C2 (ru) | 2002-02-01 | 2008-11-10 | Ф.Хоффманн-Ля Рош Аг | Замещенные индолы и фармацевтическая композиция, обладающая агонистической активностью в отношении альфа-1a/l адренорецептора |
| SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| AU2003211427A1 (en) | 2002-02-18 | 2003-09-04 | Ishihara Sangyo Kaisha, Ltd. | Pyridine derivatives or salts thereof and cytokine production inhibitors containing the same |
| CA2479338A1 (en) | 2002-03-20 | 2003-10-02 | Metabolex, Inc. | Substituted phenylacetic acids |
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| AU2003231509A1 (en) * | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| PE20040844A1 (es) | 2002-11-26 | 2004-12-30 | Novartis Ag | Acidos fenilaceticos y derivados como inhibidores de la cox-2 |
| PL377314A1 (pl) | 2002-12-20 | 2006-01-23 | Amgen Inc. | Modulatory astmy i zapaleń na tle alergicznym |
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| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301009D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| PT1471057E (pt) | 2003-04-25 | 2006-05-31 | Actimis Pharmaceuticals Inc | Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2 |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| US7166738B2 (en) | 2004-04-23 | 2007-01-23 | Roche Palo Alto Llc | Non-nucleoside reverse transcriptase inhibitors |
| GB0409921D0 (en) | 2004-05-04 | 2004-06-09 | Novartis Ag | Organic compounds |
| EP1758579A1 (en) | 2004-05-29 | 2007-03-07 | 7TM Pharma A/S | Crth2 receptor ligands for medicinal uses |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
| GB0510584D0 (en) | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| EP1937632A1 (en) | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| EP1948630A2 (en) | 2005-11-05 | 2008-07-30 | AstraZeneca AB | Novel compounds |
| TW200732296A (en) | 2005-12-15 | 2007-09-01 | Astrazeneca Ab | Novel compounds |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
-
2004
- 2004-08-15 SA SA4250253A patent/SA04250253B1/ar unknown
- 2004-08-16 TW TW093124572A patent/TWI347313B/zh not_active IP Right Cessation
- 2004-08-18 AT AT04768111T patent/ATE427296T1/de active
- 2004-08-18 US US10/569,065 patent/US8003703B2/en not_active Expired - Fee Related
- 2004-08-18 DK DK04768111T patent/DK1660431T3/da active
- 2004-08-18 KR KR1020067003429A patent/KR101136175B1/ko not_active Expired - Fee Related
- 2004-08-18 HR HR20090280T patent/HRP20090280T1/xx unknown
- 2004-08-18 MX MXPA06001954A patent/MXPA06001954A/es active IP Right Grant
- 2004-08-18 EP EP04768111A patent/EP1660431B1/en not_active Expired - Lifetime
- 2004-08-18 BR BRPI0413490-7A patent/BRPI0413490A/pt not_active IP Right Cessation
- 2004-08-18 AU AU2004266485A patent/AU2004266485B2/en not_active Ceased
- 2004-08-18 SI SI200431118T patent/SI1660431T1/sl unknown
- 2004-08-18 WO PCT/GB2004/003551 patent/WO2005018529A2/en not_active Ceased
- 2004-08-18 NZ NZ545450A patent/NZ545450A/en not_active IP Right Cessation
- 2004-08-18 JP JP2006523683A patent/JP5025264B2/ja not_active Expired - Fee Related
- 2004-08-18 CA CA2535714A patent/CA2535714C/en not_active Expired - Fee Related
- 2004-08-18 PT PT04768111T patent/PT1660431E/pt unknown
- 2004-08-18 ES ES04768111T patent/ES2322653T3/es not_active Expired - Lifetime
- 2004-08-18 PL PL04768111T patent/PL1660431T3/pl unknown
- 2004-08-18 DE DE602004020356T patent/DE602004020356D1/de not_active Expired - Lifetime
- 2004-08-18 RU RU2006107653/04A patent/RU2360901C2/ru not_active IP Right Cessation
- 2004-08-19 MY MYPI20043374A patent/MY142029A/en unknown
- 2004-08-20 AR ARP040102990A patent/AR045470A1/es not_active Application Discontinuation
- 2004-08-20 UY UY28482A patent/UY28482A1/es not_active Application Discontinuation
-
2006
- 2006-02-02 IL IL173522A patent/IL173522A/en not_active IP Right Cessation
- 2006-02-16 CO CO06015646A patent/CO5670367A2/es not_active Application Discontinuation
- 2006-03-13 IS IS8350A patent/IS2693B/is unknown
-
2009
- 2009-05-28 CY CY20091100565T patent/CY1110318T1/el unknown
-
2011
- 2011-07-26 US US13/190,881 patent/US8394986B2/en not_active Expired - Fee Related
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