JP2008520208A - タンパク質骨格およびその使用 - Google Patents

タンパク質骨格およびその使用 Download PDF

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Publication number
JP2008520208A
JP2008520208A JP2007541485A JP2007541485A JP2008520208A JP 2008520208 A JP2008520208 A JP 2008520208A JP 2007541485 A JP2007541485 A JP 2007541485A JP 2007541485 A JP2007541485 A JP 2007541485A JP 2008520208 A JP2008520208 A JP 2008520208A
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Japan
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monomer
domain
domains
library
monomer domain
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JP2007541485A
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English (en)
Japanese (ja)
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JP2008520208A5 (fr
Inventor
ウィレム ピー． シー． ステマー
ジョシュ シルバーマン
ヨースト エイ． コルクマン
マーティン フォークト
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アヴィディア リサーチ インスティテュート
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Publication of JP2008520208A publication Critical patent/JP2008520208A/ja
Publication of JP2008520208A5 publication Critical patent/JP2008520208A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2007541485A 2004-11-16 2005-11-16 タンパク質骨格およびその使用 Withdrawn JP2008520208A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62859604P 2004-11-16 2004-11-16
PCT/US2005/041639 WO2006127040A2 (fr) 2004-11-16 2005-11-16 Squelettes proteiques et leurs utilisations

Publications (2)

Publication Number Publication Date
JP2008520208A true JP2008520208A (ja) 2008-06-19
JP2008520208A5 JP2008520208A5 (fr) 2008-12-25

Family

ID=37452497

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007541485A Withdrawn JP2008520208A (ja) 2004-11-16 2005-11-16 タンパク質骨格およびその使用

Country Status (6)

Country Link
EP (1) EP1817444A4 (fr)
JP (1) JP2008520208A (fr)
AU (1) AU2005332022A1 (fr)
CA (1) CA2587463A1 (fr)
MX (1) MX2007005865A (fr)
WO (1) WO2006127040A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12030925B2 (en) 2018-05-18 2024-07-09 Bioverativ Therapeutics Inc. Methods of treating hemophilia A
US12161696B2 (en) 2016-12-02 2024-12-10 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040715A2 (fr) 1999-01-05 2000-07-13 Trustees Of Boston University Ligature perfectionnee d'acides nucleiques
US20040005673A1 (en) 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
US7435562B2 (en) 2000-07-21 2008-10-14 Modular Genetics, Inc. Modular vector systems
EP1817413B1 (fr) 2004-11-11 2012-01-04 Modular Genetics, Inc. Ensemble et système d'échelle d'oligonucléotide pour produire de la diversité moléculaire
EP2408814B1 (fr) 2009-03-20 2018-11-21 Amgen Inc. Immunoglobulines porteuses et utilisations de celles-ci
WO2012040518A2 (fr) 2010-09-22 2012-03-29 Amgen Inc. Immunoglobulines porteuses et leur utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030157561A1 (en) * 2001-11-19 2003-08-21 Kolkman Joost A. Combinatorial libraries of monomer domains
DK1390535T3 (da) * 2001-04-26 2010-12-06 Amgen Mountain View Inc Kombinatoriske biblioteker af monomer-domæner
US7655411B2 (en) * 2002-08-23 2010-02-02 W2 Holdings, Inc. Thrombospondin fragments and binding agents in the detection, diagnosis and evaluation of cancer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161696B2 (en) 2016-12-02 2024-12-10 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors
US12030925B2 (en) 2018-05-18 2024-07-09 Bioverativ Therapeutics Inc. Methods of treating hemophilia A

Also Published As

Publication number Publication date
WO2006127040A3 (fr) 2009-04-09
EP1817444A4 (fr) 2010-02-17
MX2007005865A (es) 2008-02-25
AU2005332022A1 (en) 2006-11-30
EP1817444A2 (fr) 2007-08-15
WO2006127040A2 (fr) 2006-11-30
CA2587463A1 (fr) 2006-11-30

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