JP2009509143A - 分析改善システムおよび方法 - Google Patents

分析改善システムおよび方法 Download PDF

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Publication number
JP2009509143A
JP2009509143A JP2008531396A JP2008531396A JP2009509143A JP 2009509143 A JP2009509143 A JP 2009509143A JP 2008531396 A JP2008531396 A JP 2008531396A JP 2008531396 A JP2008531396 A JP 2008531396A JP 2009509143 A JP2009509143 A JP 2009509143A
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Prior art keywords
cells
sample
specimen
analyte
fetal
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Japanese (ja)
Inventor
カプー，ラヴィ
トナー，メメット
ファン，ローティン，リチャード
バーバー，トム
カルヴァーリョ，ブルース
グレイ，ダレン
バリス，ユリシス
ウォルシュ，ジョン
グリシャム，マイケル
トンプキンス，ロン
シュミット，マーティン
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アルテミス ヘルス，インク．
ザ・ゼネラル・ホスピタル・コーポレーション
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Priority claimed from US11/228,454 external-priority patent/US20070059716A1/en
Priority claimed from US11/229,332 external-priority patent/US20070059719A1/en
Priority claimed from US11/229,037 external-priority patent/US20070059774A1/en
Priority claimed from US11/229,336 external-priority patent/US20070059781A1/en
Priority claimed from US11/228,462 external-priority patent/US20070059680A1/en
Priority claimed from US11/229,328 external-priority patent/US20070059718A1/en
Application filed by アルテミス ヘルス，インク．, ザ・ゼネラル・ホスピタル・コーポレーション filed Critical アルテミス ヘルス，インク．
Publication of JP2009509143A publication Critical patent/JP2009509143A/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805—Haemoglobins; Myoglobins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/38—Pediatrics
    • G01N2800/385—Congenital anomalies
    • G01N2800/387—Down syndrome; Trisomy 18; Trisomy 13
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

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  • Biotechnology (AREA)
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  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
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  • Food Science & Technology (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
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  • Clinical Laboratory Science (AREA)
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  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2008531396A 2005-09-15 2006-09-15 分析改善システムおよび方法 Withdrawn JP2009509143A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11/228,454 US20070059716A1 (en) 2005-09-15 2005-09-15 Methods for detecting fetal abnormality
US11/229,332 US20070059719A1 (en) 2005-09-15 2005-09-15 Business methods for prenatal Diagnosis
US11/229,037 US20070059774A1 (en) 2005-09-15 2005-09-15 Kits for Prenatal Testing
US11/229,336 US20070059781A1 (en) 2005-09-15 2005-09-15 System for size based separation and analysis
US11/228,462 US20070059680A1 (en) 2005-09-15 2005-09-15 System for cell enrichment
US11/229,328 US20070059718A1 (en) 2005-09-15 2005-09-15 Systems and methods for enrichment of analytes
PCT/US2006/036202 WO2007035585A2 (fr) 2005-09-15 2006-09-15 Systemes et methodes d'enrichissement d'analytes

Publications (1)

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JP2009509143A true JP2009509143A (ja) 2009-03-05

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JP2008531396A Withdrawn JP2009509143A (ja) 2005-09-15 2006-09-15 分析改善システムおよび方法

Country Status (6)

Country Link
EP (1) EP1931800A4 (fr)
JP (1) JP2009509143A (fr)
AU (1) AU2006292394A1 (fr)
CA (1) CA2622745A1 (fr)
IL (1) IL190090A0 (fr)
WO (1) WO2007035585A2 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009273461A (ja) * 2008-05-13 2009-11-26 Commissariat A L'energie Atomique 細胞集団を選別するため、および選別後の細胞集団を連続的にカプセル化するためのマイクロ流体システムおよび方法
JP2012088055A (ja) * 2010-09-21 2012-05-10 Tokyo Univ Of Agriculture & Technology 微量血液からの白血球ポピュレーション解析法
JP2012524894A (ja) * 2009-04-23 2012-10-18 ダブリン シティ ユニバーシティ 凝固をモニタするための側方流動分析装置及びその方法
JP2015051430A (ja) * 2013-08-06 2015-03-19 旭化成株式会社 マイクロ流路構造体及び粒子の分離方法
WO2020184500A1 (fr) * 2019-03-14 2020-09-17 株式会社カネカ Programme, procédé de création de modèle d'apprentissage, dispositif vestimentaire, dispositif de traitement d'informations et procédé de traitement d'informations
JPWO2022070841A1 (fr) * 2020-09-29 2022-04-07
JP2023501438A (ja) * 2019-11-15 2023-01-18 レッドバッド ラブズ インコーポレイテッド 表面に取り付けられたポストおよびマイクロ流体チャンバー内の捕捉ビーズを使用するためのマイクロ流体デバイスおよび方法
JP2023518854A (ja) * 2020-03-25 2023-05-08 アウフバウ・メディカル・イノベイションズ・リミテッド 細胞外マトリックス体を単離するための装置および方法

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CN103382434B (zh) 2005-01-18 2016-05-25 生物概念股份有限公司 利用含排列成图案的立柱的微通道分离细胞
US20090136982A1 (en) 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
US8158410B2 (en) 2005-01-18 2012-04-17 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
EP1874920A4 (fr) * 2005-04-05 2009-11-04 Cellpoint Diagnostics Dispositifs et procédés permettant d'enrichir et de modifier des cellules tumorales circulantes et d'autres particules
US7695956B2 (en) 2006-01-12 2010-04-13 Biocept, Inc. Device for cell separation and analysis and method of using
EP2589668A1 (fr) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse de cellules rares utilisant la division d'échantillons et les marqueurs d'ADN
WO2009035447A1 (fr) * 2006-06-14 2009-03-19 Living Microsystems, Inc. Diagnostic d'anomalies fœtales par une analyse par hybridation génomique comparative
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
WO2010041231A2 (fr) * 2008-10-10 2010-04-15 Cnrs-Dae Dispositif de tri de cellules
SG184592A1 (en) * 2011-03-18 2012-10-30 Univ Singapore Isolating target cells from a biological fluid
US10174364B2 (en) 2010-07-16 2019-01-08 Stichting Vu-Vumc Method of analysing a blood sample of a subject for the presence of a disease marker
US10174365B2 (en) 2011-03-18 2019-01-08 Stichting Vu-Vumc Method of analysing a blood sample of a subject for the presence of a disease marker
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
EP3608022A1 (fr) 2013-03-15 2020-02-12 The Trustees of Princeton University Procédés et dispositifs de purification à haut rendement
US11493428B2 (en) 2013-03-15 2022-11-08 Gpb Scientific, Inc. On-chip microfluidic processing of particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
ES1111981Y (es) 2014-05-22 2014-09-03 Ayet Félix Checa Protesis quirurgica para el tratamiento de hernias inguinales
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
ES2818569T3 (es) 2015-09-09 2021-04-13 Drawbridge Health Inc Métodos para la recopilación, estabilización y conservación de muestras
GB2590814B (en) 2017-01-10 2021-11-03 Drawbridge Health Inc Devices, systems, and methods for sample collection
CN111065399B (zh) 2017-09-01 2023-11-28 Gpb科学有限公司 使用微流体制备治疗活性细胞的方法
CN116312809B (zh) * 2023-04-10 2023-08-29 杭州美赛生物医药科技有限公司 一种基于抗体偶联磁珠的细胞筛选方法

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US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
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US6613581B1 (en) * 1999-08-26 2003-09-02 Caliper Technologies Corp. Microfluidic analytic detection assays, devices, and integrated systems
WO2002030562A1 (fr) * 2000-10-10 2002-04-18 Aviva Biosciences Corporation Système à biopuce intégrée pour la préparation et l'analyse d'échantillons
CA2462914A1 (fr) * 2001-10-11 2003-04-17 Aviva Biosciences Corporation Methodes, compositions, et systemes automatises pour la separation des cellules rares provenant d'echantillons de fluides
EP2359689B1 (fr) * 2002-09-27 2015-08-26 The General Hospital Corporation Dispositif microfluidique pour la séparation de cellules et usage du dispositif
EP1585583B1 (fr) * 2002-10-23 2010-04-07 The Trustees of Princeton University Procede de separation continue de particules faisant appel a des reseaux d'obstacles alignes de maniere asymetrique par rapport a des champs

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009273461A (ja) * 2008-05-13 2009-11-26 Commissariat A L'energie Atomique 細胞集団を選別するため、および選別後の細胞集団を連続的にカプセル化するためのマイクロ流体システムおよび方法
JP2012524894A (ja) * 2009-04-23 2012-10-18 ダブリン シティ ユニバーシティ 凝固をモニタするための側方流動分析装置及びその方法
JP2012088055A (ja) * 2010-09-21 2012-05-10 Tokyo Univ Of Agriculture & Technology 微量血液からの白血球ポピュレーション解析法
JP2015051430A (ja) * 2013-08-06 2015-03-19 旭化成株式会社 マイクロ流路構造体及び粒子の分離方法
WO2020184500A1 (fr) * 2019-03-14 2020-09-17 株式会社カネカ Programme, procédé de création de modèle d'apprentissage, dispositif vestimentaire, dispositif de traitement d'informations et procédé de traitement d'informations
JP2023501438A (ja) * 2019-11-15 2023-01-18 レッドバッド ラブズ インコーポレイテッド 表面に取り付けられたポストおよびマイクロ流体チャンバー内の捕捉ビーズを使用するためのマイクロ流体デバイスおよび方法
JP2023518854A (ja) * 2020-03-25 2023-05-08 アウフバウ・メディカル・イノベイションズ・リミテッド 細胞外マトリックス体を単離するための装置および方法
JP7756931B2 (ja) 2020-03-25 2025-10-21 アウフバウ・メディカル・イノベイションズ・リミテッド 細胞外マトリックス体を単離するための装置および方法
JPWO2022070841A1 (fr) * 2020-09-29 2022-04-07
WO2022070841A1 (fr) * 2020-09-29 2022-04-07 Nok株式会社 Appareil de piégeage de leucocytes
JP7455339B2 (ja) 2020-09-29 2024-03-26 Nok株式会社 白血球捕捉デバイス
US12599903B2 (en) 2020-09-29 2026-04-14 Nok Corporation Leukocyte trapping apparatus

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EP1931800A2 (fr) 2008-06-18
AU2006292394A1 (en) 2007-03-29
IL190090A0 (en) 2008-08-07
CA2622745A1 (fr) 2007-03-29
WO2007035585A2 (fr) 2007-03-29
WO2007035585A3 (fr) 2007-11-29

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