JP2010142232A5 - - Google Patents

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Publication number
JP2010142232A5
JP2010142232A5 JP2009297339A JP2009297339A JP2010142232A5 JP 2010142232 A5 JP2010142232 A5 JP 2010142232A5 JP 2009297339 A JP2009297339 A JP 2009297339A JP 2009297339 A JP2009297339 A JP 2009297339A JP 2010142232 A5 JP2010142232 A5 JP 2010142232A5
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JP
Japan
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JP2009297339A
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JP5133969B2 (ja
JP2010142232A (ja
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Publication of JP2010142232A publication Critical patent/JP2010142232A/ja
Publication of JP2010142232A5 publication Critical patent/JP2010142232A5/ja
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Publication of JP5133969B2 publication Critical patent/JP5133969B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2009297339A 2002-05-10 2009-12-28 加ピロリン酸分解活性化重合(pap) Expired - Fee Related JP5133969B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37909202P 2002-05-10 2002-05-10
US60/379,092 2002-05-10

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2004503654A Division JP4500673B2 (ja) 2002-05-10 2003-05-09 加ピロリン酸分解活性化重合(pap)

Publications (3)

Publication Number Publication Date
JP2010142232A JP2010142232A (ja) 2010-07-01
JP2010142232A5 true JP2010142232A5 (ja) 2010-09-09
JP5133969B2 JP5133969B2 (ja) 2013-01-30

Family

ID=29420484

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004503654A Expired - Fee Related JP4500673B2 (ja) 2002-05-10 2003-05-09 加ピロリン酸分解活性化重合(pap)
JP2009297339A Expired - Fee Related JP5133969B2 (ja) 2002-05-10 2009-12-28 加ピロリン酸分解活性化重合(pap)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2004503654A Expired - Fee Related JP4500673B2 (ja) 2002-05-10 2003-05-09 加ピロリン酸分解活性化重合(pap)

Country Status (6)

Country Link
EP (2) EP2292787B1 (ja)
JP (2) JP4500673B2 (ja)
AT (1) ATE552349T1 (ja)
AU (1) AU2003241401B8 (ja)
CA (2) CA2485596C (ja)
WO (1) WO2003095664A2 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0406863D0 (en) * 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
GB0406864D0 (en) 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
ES2553893T3 (es) * 2007-11-28 2015-12-14 F. Hoffmann-La Roche Ag ADN polimerasas mutantes con capacidad mejorada de polimerización activada por pirofosforolisis (PAP)
CN101381766B (zh) * 2008-06-11 2012-04-18 厦门大学 一种基因稀有突变的定量检测方法
CN103492587B (zh) * 2010-12-13 2015-02-18 生命技术公司 利用通过多磷酸分解作用(app)反应的活化聚合核酸
WO2012151328A2 (en) 2011-05-02 2012-11-08 President And Fellows Of Harvard College Spatial sequestration of dynamic nucleic acid circuits
WO2013119888A1 (en) 2012-02-09 2013-08-15 President And Fellows Of Harvard College Selective nucleic acid amplification from nucleic acid pools
US8895249B2 (en) * 2012-06-15 2014-11-25 Illumina, Inc. Kinetic exclusion amplification of nucleic acid libraries
US11261494B2 (en) * 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
CN103266103B (zh) * 2012-11-08 2016-08-31 天津精耐特基因生物技术有限公司 用于扩增核糖核酸的方法及分析该方法中rna或dna模板的方法
JP2016524917A (ja) * 2013-07-18 2016-08-22 プレジデント アンド フェローズ オブ ハーバード カレッジ 複合的な選択性を有する特異的核酸増幅
CN108410980B (zh) * 2018-01-22 2022-02-01 华大数极生物科技(深圳)有限公司 筛选甲基化pcr检测的目标区域的方法、试剂盒及应用
US11268140B2 (en) * 2018-06-12 2022-03-08 Shaofeng Ding Delayed pyrophosphorolysis activated polymerization
KR102589502B1 (ko) 2018-07-19 2023-10-13 바이오피델리티 엘티디 개선된 폴리뉴클레오티드 서열 탐지 방법
GB201919186D0 (en) * 2019-12-23 2020-02-05 Biofidelity Ltd Simplified polynucleotide sequence detection method
WO2022175655A1 (en) * 2021-02-16 2022-08-25 Biofidelity Ltd Methods for polynucleotide detection
WO2022219408A1 (en) * 2021-04-15 2022-10-20 Biofidelity Nucleic acid enrichment and detection
CN115308079B (zh) * 2022-08-26 2024-03-29 攀钢集团重庆钒钛科技有限公司 一种实验室钛精矿酸解率的表征方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340806C (en) 1986-07-02 1999-11-02 James Merrill Prober Method, system and reagents for dna sequencing
US6268146B1 (en) * 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US20020048760A1 (en) * 1999-12-10 2002-04-25 Hyseq, Inc. Use of mismatch cleavage to detect complementary probes
US6534269B2 (en) * 2000-02-23 2003-03-18 City Of Hope Pyrophosphorolysis activated polymerization (PAP): application to allele-specific amplification and nucleic acid sequence determination
WO2001062952A1 (en) * 2000-02-24 2001-08-30 Dna Sciences, Inc. Methods for determining single nucleotide variations

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