JP2010142232A5 - - Google Patents
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- Publication number
- JP2010142232A5 JP2010142232A5 JP2009297339A JP2009297339A JP2010142232A5 JP 2010142232 A5 JP2010142232 A5 JP 2010142232A5 JP 2009297339 A JP2009297339 A JP 2009297339A JP 2009297339 A JP2009297339 A JP 2009297339A JP 2010142232 A5 JP2010142232 A5 JP 2010142232A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37909202P | 2002-05-10 | 2002-05-10 | |
| US60/379,092 | 2002-05-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004503654A Division JP4500673B2 (ja) | 2002-05-10 | 2003-05-09 | 加ピロリン酸分解活性化重合（ｐａｐ） |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010142232A JP2010142232A (ja) | 2010-07-01 |
| JP2010142232A5 true JP2010142232A5 (ja) | 2010-09-09 |
| JP5133969B2 JP5133969B2 (ja) | 2013-01-30 |
Family
ID=29420484
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004503654A Expired - Fee Related JP4500673B2 (ja) | 2002-05-10 | 2003-05-09 | 加ピロリン酸分解活性化重合（ｐａｐ） |
| JP2009297339A Expired - Fee Related JP5133969B2 (ja) | 2002-05-10 | 2009-12-28 | 加ピロリン酸分解活性化重合（ｐａｐ） |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004503654A Expired - Fee Related JP4500673B2 (ja) | 2002-05-10 | 2003-05-09 | 加ピロリン酸分解活性化重合（ｐａｐ） |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1509619B1 (ja) |
| JP (2) | JP4500673B2 (ja) |
| AT (1) | ATE552349T1 (ja) |
| AU (1) | AU2003241401B8 (ja) |
| CA (2) | CA2805053A1 (ja) |
| WO (1) | WO2003095664A2 (ja) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0406863D0 (en) * | 2004-03-26 | 2004-04-28 | Qiagen As | Nucleic acid sequencing |
| GB0406864D0 (en) * | 2004-03-26 | 2004-04-28 | Qiagen As | Nucleic acid sequencing |
| US7745125B2 (en) * | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| WO2009068268A1 (en) * | 2007-11-28 | 2009-06-04 | Roche Diagnostics Gmbh | Mutant dna polymerases with improved pyrophosphorolysis activated polymerization (pap) ability |
| CN101381766B (zh) * | 2008-06-11 | 2012-04-18 | 厦门大学 | 一种基因稀有突变的定量检测方法 |
| US8932813B2 (en) | 2010-12-13 | 2015-01-13 | Life Technologies Corporation | Polymerization of nucleic acids using activation by polyphosphorolysis (APP) reactions |
| US9796748B2 (en) | 2011-05-02 | 2017-10-24 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
| US9862994B2 (en) | 2012-02-09 | 2018-01-09 | Dana-Farber Cancer Institute, Inc. | Selective nucleic acid amplification from nucleic acid pools |
| US8895249B2 (en) * | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
| US11261494B2 (en) * | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
| CN103266103B (zh) * | 2012-11-08 | 2016-08-31 | 天津精耐特基因生物技术有限公司 | 用于扩增核糖核酸的方法及分析该方法中rna或dna模板的方法 |
| EP3022323B1 (en) * | 2013-07-18 | 2019-04-24 | President and Fellows of Harvard College | Specific nucleic acid amplification with compounded selectivity |
| CN108410980B (zh) * | 2018-01-22 | 2022-02-01 | 华大数极生物科技(深圳)有限公司 | 筛选甲基化pcr检测的目标区域的方法、试剂盒及应用 |
| US11268140B2 (en) * | 2018-06-12 | 2022-03-08 | Shaofeng Ding | Delayed pyrophosphorolysis activated polymerization |
| JP6947464B2 (ja) | 2018-07-19 | 2021-10-13 | バイオフィデリティ・リミテッド | 改善されたポリヌクレオチド配列検出法 |
| GB201919186D0 (en) | 2019-12-23 | 2020-02-05 | Biofidelity Ltd | Simplified polynucleotide sequence detection method |
| EP4294944A1 (en) * | 2021-02-16 | 2023-12-27 | Biofidelity Ltd | Methods for polynucleotide detection |
| US11634754B2 (en) | 2021-04-15 | 2023-04-25 | Biofidelity Ltd. | Nucleic acid enrichment and detection |
| CN115308079B (zh) * | 2022-08-26 | 2024-03-29 | 攀钢集团重庆钒钛科技有限公司 | 一种实验室钛精矿酸解率的表征方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340806C (en) | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
| US6268146B1 (en) * | 1998-03-13 | 2001-07-31 | Promega Corporation | Analytical methods and materials for nucleic acid detection |
| US20020048760A1 (en) * | 1999-12-10 | 2002-04-25 | Hyseq, Inc. | Use of mismatch cleavage to detect complementary probes |
| DE60139762D1 (de) * | 2000-02-23 | 2009-10-15 | Hope City | Pyrophosphorolyse-aktivierte polymerisierung (pap): anwendung für allel-spezifische amplifizierung und sequenzbestimmung von nukleinsäuren |
| WO2001062952A1 (en) * | 2000-02-24 | 2001-08-30 | Dna Sciences, Inc. | Methods for determining single nucleotide variations |
-
2003
- 2003-05-09 EP EP03731135A patent/EP1509619B1/en not_active Expired - Lifetime
- 2003-05-09 CA CA2805053A patent/CA2805053A1/en not_active Abandoned
- 2003-05-09 AU AU2003241401A patent/AU2003241401B8/en not_active Ceased
- 2003-05-09 CA CA2485596A patent/CA2485596C/en not_active Expired - Fee Related
- 2003-05-09 EP EP10183576.7A patent/EP2292787B1/en not_active Expired - Lifetime
- 2003-05-09 WO PCT/US2003/014556 patent/WO2003095664A2/en not_active Ceased
- 2003-05-09 AT AT03731135T patent/ATE552349T1/de active
- 2003-05-09 JP JP2004503654A patent/JP4500673B2/ja not_active Expired - Fee Related
-
2009
- 2009-12-28 JP JP2009297339A patent/JP5133969B2/ja not_active Expired - Fee Related