JP2012503626A - プロテアーゼ阻害剤 - Google Patents

プロテアーゼ阻害剤 Download PDF

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Publication number: JP2012503626A
Authority: JP; Japan
Prior art keywords: methyl; fluoro; acid; alkyl; compound according
Prior art date: 2008-09-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2011528327A

Other languages

English (en)

Japanese (ja)

Inventor

イワノフ，ウラジミール

サミュエルソン，ベルティル

ヨハンソン，ペル−オラ

カーンベルグ，ピア

ヴェーリング，ホルスト

Original Assignee

メディヴィル・アクチエボラーグ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-09-24

Filing date

2009-09-24

Publication date

2012-02-09

2009-09-24 Application filed by メディヴィル・アクチエボラーグ filed Critical メディヴィル・アクチエボラーグ

2012-02-09 Publication of JP2012503626A publication Critical patent/JP2012503626A/ja

Status Pending legal-status Critical Current

Links

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125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 26
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

JP2011528327A 2008-09-24 2009-09-24 プロテアーゼ阻害剤 Pending JP2012503626A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0817425.2A GB0817425D0 (en)	2008-09-24	2008-09-24	Protease inhibitors
GB0817425.2		2008-09-24
PCT/EP2009/062407 WO2010034789A1 (en)	2008-09-24	2009-09-24	Protease inhibitors

Publications (1)

Publication Number	Publication Date
JP2012503626A true JP2012503626A (ja)	2012-02-09

Family

ID=39952075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2011528327A Pending JP2012503626A (ja)	2008-09-24	2009-09-24	プロテアーゼ阻害剤

Country Status (10)

Country	Link
EP (1)	EP2350089A1 (pt)
JP (1)	JP2012503626A (pt)
KR (1)	KR20110059657A (pt)
CN (1)	CN102224155A (pt)
AU (1)	AU2009295899A1 (pt)
BR (1)	BRPI0919073A2 (pt)
CA (1)	CA2738025A1 (pt)
EA (1)	EA201170480A1 (pt)
GB (1)	GB0817425D0 (pt)
WO (1)	WO2010034789A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB201314503D0 (en) *	2013-08-13	2013-09-25	Medivir Ab	Cysteine protease inhibitor salt
AU2020250933A1 (en)	2019-04-05	2021-10-28	Centre Hospitalier Régional Et Universitaire De Brest	Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0003111D0 (en) *	2000-02-10	2000-03-29	Novartis Ag	Organic compounds
SE0400022D0 (sv) *	2004-01-08	2004-01-08	Medivir Ab	New compounds
GB0614052D0 (en) *	2006-07-14	2006-08-23	Amura Therapeutics Ltd	Compounds

2008
- 2008-09-24 GB GBGB0817425.2A patent/GB0817425D0/en not_active Ceased
2009
- 2009-09-24 EA EA201170480A patent/EA201170480A1/ru unknown
- 2009-09-24 CA CA2738025A patent/CA2738025A1/en not_active Abandoned
- 2009-09-24 JP JP2011528327A patent/JP2012503626A/ja active Pending
- 2009-09-24 WO PCT/EP2009/062407 patent/WO2010034789A1/en not_active Ceased
- 2009-09-24 AU AU2009295899A patent/AU2009295899A1/en not_active Abandoned
- 2009-09-24 EP EP09783392A patent/EP2350089A1/en not_active Withdrawn
- 2009-09-24 BR BRPI0919073A patent/BRPI0919073A2/pt not_active Application Discontinuation
- 2009-09-24 KR KR1020117009282A patent/KR20110059657A/ko not_active Withdrawn
- 2009-09-24 CN CN2009801480408A patent/CN102224155A/zh active Pending

Also Published As

Publication number	Publication date
BRPI0919073A2 (pt)	2016-03-15
CA2738025A1 (en)	2010-04-01
EA201170480A1 (ru)	2011-12-30
EP2350089A1 (en)	2011-08-03
AU2009295899A1 (en)	2010-04-01
KR20110059657A (ko)	2011-06-02
GB0817425D0 (en)	2008-10-29
WO2010034789A1 (en)	2010-04-01
CN102224155A (zh)	2011-10-19

Publication	Publication Date	Title
US12378209B2 (en)	2025-08-05	Protease inhibitors
JP5501961B2 (ja)	2014-05-28	システインプロテアーゼ阻害剤
JP2012503626A (ja)	2012-02-09	プロテアーゼ阻害剤
WO2008114054A1 (en)	2008-09-25	Protease inhibitors
HK1152522B (en)	2013-12-20	Protease inhibitors